PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Pbr019774.1

Organism

Pyrus bretschneideri

Taxonomic ID

225117

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus

Family

MYB_related

Protein Properties

Length: 1457aa MW: 164234 Da PI: 4.8951

Description

MYB_related family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pbr019774.1	genome	CPETR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	31.4	4.3e-10	1379	1432	1	46
TSSS-HHHHHHHHHHHHHTTTT....-HHHHHHHHT....TTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGgg....tWktIartmg....kgRtlkqcksrwqk 46 r+ WT eE+e+l+++v+ +++ +Wk+I + k Rt+++++++w k Pbr019774.1 1379 RLYWTREEEEKLKELVNSFPTTgknrCWKKILENGRdvfhKDRTPNDLRNKWGK 1432 788*************************************************66 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.40.850.10	4.9E-107	70	403	IPR001752	Kinesin motor domain
SMART	SM00129	1.1E-124	71	402	IPR001752	Kinesin motor domain
PROSITE profile	PS50067	104.861	73	394	IPR001752	Kinesin motor domain
SuperFamily	SSF52540	5.91E-99	73	430	IPR027417	P-loop containing nucleoside triphosphate hydrolase
CDD	cd01374	5.33E-151	73	394	No hit	No description
Pfam	PF00225	5.5E-93	80	394	IPR001752	Kinesin motor domain
PRINTS	PR00380	6.8E-37	149	170	IPR001752	Kinesin motor domain
PRINTS	PR00380	6.8E-37	259	276	IPR001752	Kinesin motor domain
PROSITE pattern	PS00411	0	292	303	IPR019821	Kinesin motor domain, conserved site
PRINTS	PR00380	6.8E-37	293	311	IPR001752	Kinesin motor domain
PRINTS	PR00380	6.8E-37	344	365	IPR001752	Kinesin motor domain
Gene3D	G3DSA:3.30.40.10	2.2E-4	984	1033	IPR013083	Zinc finger, RING/FYVE/PHD-type
PROSITE profile	PS51294	10.239	1374	1438	IPR017930	Myb domain
SuperFamily	SSF46689	1.35E-6	1375	1436	IPR009057	Homeodomain-like
SMART	SM00717	7.6E-6	1378	1436	IPR001005	SANT/Myb domain
Pfam	PF00249	9.8E-8	1380	1432	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	6.1E-9	1381	1432	IPR009057	Homeodomain-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0007018	Biological Process	microtubule-based movement
GO:0003677	Molecular Function	DNA binding
GO:0003777	Molecular Function	microtubule motor activity
GO:0005524	Molecular Function	ATP binding
GO:0008017	Molecular Function	microtubule binding

Sequence ? help Back to Top
Protein Sequence Length: 1457 aa Download sequence Send to blast
MLSNNQHWIL ITTAAVEADT LLEAAEEVED TPAPDSLVLE DNHRLHFAKS QGQAYIMMMA 60 SRTPGTPRAK KEKIVVLVCL RPLSKREELA KEQVSWDCLG DNTIVYKPPP HERSTQSASF 120 TFDKVFGPGS TEAVYEEGVR NVALSSLMGI NATIFAYGQS GSGKTYTMKG IMEKAVDDIY 180 NHITNTPERE FGIKISGLEI YNENVRDLLN TESVGNLKLL DDPEKGIVVE KLVEEAASSH 240 QHLRSLIGIC EAQREVGETA LNDNSSRSHQ IIRLTIESTV RESLDCRTSF VASLNFVDLA 300 GSERAPETHA DGVRLREGCH INLSLMTLTN VIRKLSAGKL SGHIPYRDSK LTRILQHSLG 360 GNARTAIICT LSPALSHAEQ SRNTLFFATQ AKEVTNDASV NTVVSDKQLV KHLQKQVAKL 420 EAELYTLYPL RERIQQMEME MEDLRSERDL AHSQADELRH KLEVQSLYPL ELPHRSVDNY 480 LSYTGVLPIS FYAKELGDCD TATNARTKHS IRHSSTPPFM PRREVLKHEI SSEQLSEEPS 540 RALKLKVLYK SKLVIPPCIQ DLAFRCLEDL FRPQINSLLL STQAKGESNM VVPDKKLVKR 600 LQMEVLRRET EVPTVSREED LRIQKVLNQL ELPHPYVKKL IFCIGALPAT FYAEELGGGD 660 RARNTMIRHS MRLSSFAPFT LNHEILRLEV LLVQLGEGPC RALEIVLQKE VAMHGLENHD 720 RARNTMIRHP IRLSSFAPFM LNREILKLEV LLAQLGEGPS RALEIVLQKE VAWQGLENQD 780 AGETFCNLQA EIKETHYTSS RPKEFEVGSL VPVNKNEIPR LHSQGSAIAN LEEQFPNVQY 840 VTDKLVSLPC IQLLALRFLE DLFRPREVTG DVLEQIKNEP LIHNIVPLLG SWQEDEAEDD 900 GGFHLEPGTS IAAPPDVSAV EYDYIGEHVF HVKVEHPADR YEKKTISDEA KELMDCHRET 960 SDSSAFRNGK IDVSVENCDF LGFLCSNGGQ LLICNTSNCP SVFHQNFESD LICYKKGKYY 1020 CPICSYSLAH EKRKAVAFEE VFSGCSDGYI VDEQVNARNE SGYGCDSQFD DAQVHNQFVR 1080 VEDNEIKEGT EFEVEDENNG GNSVSCRGEG TNEIIRGGSG HQCVSELLEL QQDEETAVEE 1140 SSDKNEEDED GKRVFAEKED EIENAEFMQP ESMEVPSNTI FLSDTESPVV HKRREDNEIK 1200 EGMKFEVEDE NNDGDSVNCR GEGTNKVIRG DSEHPCVSEL LELQQDEETA VEENSDTDEE 1260 DDGKRVFAEK ENEIENAELM RPESLEMPSN TIVLSDTESP VVHKNHEKAP KSFTIVLSDS 1320 SESDASDTSS PSMEPEVSDT WSPLLGEIQP KHKAQKTSES GNQPTRSNLP LPRRRRRLRL 1380 YWTREEEEKL KELVNSFPTT GKNRCWKKIL ENGRDVFHKD RTPNDLRNKW GKMRVKGAVD 1440 HFLTLRENIC SIRKMN*

Sequence ? help Back to Top

Protein Sequence Length: 1457 aa Download sequence Send to blast

MLSNNQHWIL ITTAAVEADT LLEAAEEVED TPAPDSLVLE DNHRLHFAKS QGQAYIMMMA  60
SRTPGTPRAK KEKIVVLVCL RPLSKREELA KEQVSWDCLG DNTIVYKPPP HERSTQSASF  120
TFDKVFGPGS TEAVYEEGVR NVALSSLMGI NATIFAYGQS GSGKTYTMKG IMEKAVDDIY  180
NHITNTPERE FGIKISGLEI YNENVRDLLN TESVGNLKLL DDPEKGIVVE KLVEEAASSH  240
QHLRSLIGIC EAQREVGETA LNDNSSRSHQ IIRLTIESTV RESLDCRTSF VASLNFVDLA  300
GSERAPETHA DGVRLREGCH INLSLMTLTN VIRKLSAGKL SGHIPYRDSK LTRILQHSLG  360
GNARTAIICT LSPALSHAEQ SRNTLFFATQ AKEVTNDASV NTVVSDKQLV KHLQKQVAKL  420
EAELYTLYPL RERIQQMEME MEDLRSERDL AHSQADELRH KLEVQSLYPL ELPHRSVDNY  480
LSYTGVLPIS FYAKELGDCD TATNARTKHS IRHSSTPPFM PRREVLKHEI SSEQLSEEPS  540
RALKLKVLYK SKLVIPPCIQ DLAFRCLEDL FRPQINSLLL STQAKGESNM VVPDKKLVKR  600
LQMEVLRRET EVPTVSREED LRIQKVLNQL ELPHPYVKKL IFCIGALPAT FYAEELGGGD  660
RARNTMIRHS MRLSSFAPFT LNHEILRLEV LLVQLGEGPC RALEIVLQKE VAMHGLENHD  720
RARNTMIRHP IRLSSFAPFM LNREILKLEV LLAQLGEGPS RALEIVLQKE VAWQGLENQD  780
AGETFCNLQA EIKETHYTSS RPKEFEVGSL VPVNKNEIPR LHSQGSAIAN LEEQFPNVQY  840
VTDKLVSLPC IQLLALRFLE DLFRPREVTG DVLEQIKNEP LIHNIVPLLG SWQEDEAEDD  900
GGFHLEPGTS IAAPPDVSAV EYDYIGEHVF HVKVEHPADR YEKKTISDEA KELMDCHRET  960
SDSSAFRNGK IDVSVENCDF LGFLCSNGGQ LLICNTSNCP SVFHQNFESD LICYKKGKYY  1020
CPICSYSLAH EKRKAVAFEE VFSGCSDGYI VDEQVNARNE SGYGCDSQFD DAQVHNQFVR  1080
VEDNEIKEGT EFEVEDENNG GNSVSCRGEG TNEIIRGGSG HQCVSELLEL QQDEETAVEE  1140
SSDKNEEDED GKRVFAEKED EIENAEFMQP ESMEVPSNTI FLSDTESPVV HKRREDNEIK  1200
EGMKFEVEDE NNDGDSVNCR GEGTNKVIRG DSEHPCVSEL LELQQDEETA VEENSDTDEE  1260
DDGKRVFAEK ENEIENAELM RPESLEMPSN TIVLSDTESP VVHKNHEKAP KSFTIVLSDS  1320
SESDASDTSS PSMEPEVSDT WSPLLGEIQP KHKAQKTSES GNQPTRSNLP LPRRRRRLRL  1380
YWTREEEEKL KELVNSFPTT GKNRCWKKIL ENGRDVFHKD RTPNDLRNKW GKMRVKGAVD  1440
HFLTLRENIC SIRKMN*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1t5c_A	3e-76	69	406	1	340	Centromeric protein E
1t5c_B	3e-76	69	406	1	340	Centromeric protein E
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	1371	1377	PRRRRRL

Functional Description ? help Back to Top
Source	Description
UniProt	Probable plus end-directed motor protein that functions in the NACK-PQR (NPK1-NQK1/MEK1-NRK1) MAP kinase signaling pathway, which is essential for somatic cell cytokinesis, especially for the cell-plate formation and its expansion. Regulates the activity and the localization of NPK1 by association through the non-catalytic region of the kinase. {ECO:0000269\|PubMed:11955449, ECO:0000269\|PubMed:22006334}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Pbr019774.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: During the M phase of the cell cycle (at protein level). {ECO:0000269\|PubMed:11955449}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018504882.1	0.0	PREDICTED: uncharacterized protein LOC103955247
Swissprot	Q8S950	0.0	KN7A_TOBAC; Kinesin-like protein NACK1
TrEMBL	A0A498HN64	0.0	A0A498HN64_MALDO; Kinesin-like protein
STRING	XP_009365403.1	0.0	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF22823	2	4

Publications ? help Back to Top
Ito M, et al. G2/M-phase-specific transcription during the plant cell cycle is mediated by c-Myb-like transcription factors. Plant Cell, 2001. 13(8): p. 1891-905 [PMID:11487700] Nishihama R, et al. Expansion of the cell plate in plant cytokinesis requires a kinesin-like protein/MAPKKK complex. Cell, 2002. 109(1): p. 87-99 [PMID:11955449] Ishikawa M,Soyano T,Nishihama R,Machida Y The NPK1 mitogen-activated protein kinase kinase kinase contains a functional nuclear localization signal at the binding site for the NACK1 kinesin-like protein. Plant J., 2002. 32(5): p. 789-98 [PMID:12472693] Sasabe M, et al. Phosphorylation of a mitotic kinesin-like protein and a MAPKKK by cyclin-dependent kinases (CDKs) is involved in the transition to cytokinesis in plants. Proc. Natl. Acad. Sci. U.S.A., 2011. 108(43): p. 17844-9 [PMID:22006334]