PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pbr019788.1
Organism
Pyrus bretschneideri
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus
Family AP2
Protein Properties Length: 651aa    MW: 71418.2 Da    PI: 7.5489
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pbr019788.1genomeCPETRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP2378.2e-12295351155
          AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng.krkrfslgkfgtaeeAakaaiaarkkleg 55 
                  s+++GV++++++gr++A+++d  ++  g  rk  + g ++ +e+Aa+a++ a++k++g
  Pbr019788.1 295 SQFRGVTRHRWTGRYEAHLWDnSCKkEGqTRKGRQ-GGYDMEEKAARAYDLAALKYWG 351
                  789******************77776664346655.77******************98 PP
2AP250.64.9e-16396445355
          AP2   3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                  y+GV+++++ grW A+I  +     +k  +lg+fgt eeAa+a++ a+ k++g
  Pbr019788.1 396 YRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFGTQEEAAEAYDIAAIKFRG 445
                  9***************988532...5*************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000181.02E-17295359No hitNo description
SuperFamilySSF541711.31E-13295361IPR016177DNA-binding domain
SMARTSM003806.6E-20296365IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.3E-11296360IPR001471AP2/ERF domain
PfamPF008474.7E-9296351IPR001471AP2/ERF domain
PROSITE profilePS5103216.792296359IPR001471AP2/ERF domain
PRINTSPR003677.7E-6297308IPR001471AP2/ERF domain
SuperFamilySSF541711.83E-17394454IPR016177DNA-binding domain
CDDcd000181.08E-24394455No hitNo description
SMARTSM003801.1E-32395459IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.103.8E-18395453IPR001471AP2/ERF domain
PROSITE profilePS5103218.979395453IPR001471AP2/ERF domain
PfamPF008478.9E-11396445IPR001471AP2/ERF domain
PRINTSPR003677.7E-6435455IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 651 aa     Download sequence    Send to blast
MKSMNDHNNN NNGSSNSNNN NWFGFSLLPH MKMEDASSSS CSAALPSNNS SFYNLSSSGL  60
GCYGVGDNGN FHYSPLSVMP LKSDGSLCIM EALGRSQTEG IMPNTSPKLE DFLGGAAHDY  120
VSEEREAMAL SLDSYYNAAA EQQQQQNHHI PVHSNSYYSG IPIQGIYHNQ LEEEHSKNTQ  180
MTQMPEDLKT CWVSRQYSAH PALEHHHMNN VTMVVENGGS GSVHGGMNRG DLQSLTLSMS  240
PGSQTSCVTA PKQISPTQTE CAVAAIETKK RGCGKLGQKQ PVHRKSIDTF GQRTSQFRGV  300
TRHRWTGRYE AHLWDNSCKK EGQTRKGRQG GYDMEEKAAR AYDLAALKYW GSATHINFPL  360
DNYTAQLEEM KNMSRQEYVA HLRRKSSGFS RGASMYRGVT RHHQHGRWQA RIGRVAGNKD  420
LYLGTFGTQE EAAEAYDIAA IKFRGANAVT NFDITKYDVE KIMSSNTLLA GEFARRTKVI  480
EPNILAIEHN PPTQNNVEAN QTEINNGNSL DWKMALYQSA AQQQANSCAQ TVDQKSIGSG  540
SYRNPSFSMA LEDYIGVESV HSNQTLMDES ARVGAHFSNP SSLVTSLGSS REGSPDKSGS  600
NMLFAKPPLA SKFISPTAAA AVGSWFPSAQ LRPPAVSMSQ LPLFAAWNET *
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269|PubMed:10528263, ECO:0000269|PubMed:10639184, ECO:0000269|PubMed:10948255, ECO:0000269|PubMed:11041883, ECO:0000269|PubMed:12183381, ECO:0000269|PubMed:12271029, ECO:0000269|PubMed:12655002, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9001406, ECO:0000269|PubMed:9093862, ECO:0000269|PubMed:9118807}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPbr019788.1
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009361167.10.0PREDICTED: AP2-like ethylene-responsive transcription factor ANT isoform X1
SwissprotQ389141e-155ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
TrEMBLA0A498HPY90.0A0A498HPY9_MALDO; Uncharacterized protein
STRINGXP_009361167.10.0(Pyrus x bretschneideri)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF91634114
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G37750.11e-150AP2 family protein
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Horstman A,Willemsen V,Boutilier K,Heidstra R
    AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks.
    Trends Plant Sci., 2014. 19(3): p. 146-57
    [PMID:24280109]
  3. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  4. Wynn AN,Seaman AA,Jones AL,Franks RG
    Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development.
    Front Plant Sci, 2014. 5: p. 130
    [PMID:24778638]
  5. Randall RS, et al.
    AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
    Biol Open, 2015. 4(10): p. 1229-36
    [PMID:26340943]
  6. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  7. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  8. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  9. Han H,Krizek BA
    AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels.
    Plant Mol. Biol., 2016. 92(4-5): p. 597-612
    [PMID:27605095]
  10. Karpinska B,Alomrani SO,Foyer CH
    Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling.
    Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018.
    [PMID:28808105]
  11. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]