PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pbr026560.1
Organism
Pyrus bretschneideri
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus
Family C2H2
Protein Properties Length: 374aa    MW: 42811.5 Da    PI: 6.6724
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pbr026560.1genomeCPETRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.30.000579101323
                  ET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                  C+   Cgk+F +   L++H  +H
  Pbr026560.1  79 CSydGCGKTFIDAGALRKHSHVH 101
                  78889**************8776 PP
2zf-C2H216.52.4e-05106130123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  y+C+   Cgk F ++s LkrH   H
  Pbr026560.1 106 YVCHyeGCGKKFLDSSKLKRHFLIH 130
                  9********************8877 PP
3zf-C2H222.43.3e-07136160123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  y+Cp   Cgk Fs   nL++H++tH
  Pbr026560.1 136 YVCPheGCGKAFSLDFNLRSHMKTH 160
                  99**********************9 PP
4zf-C2H216.42.6e-05166190123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  + Cp  dCgk++ + + Lk+Hi  H
  Pbr026560.1 166 HICPypDCGKRYAHEYKLKNHIVAH 190
                  679999****************885 PP
5zf-C2H215.16.6e-05230255123
                  EEET..TTTEEESSHHHHHHHHHH.T CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                  y Cp   C+k + + + Lk H+r+ H
  Pbr026560.1 230 YACPydGCNKAYIHEYKLKLHLRReH 255
                  89**********************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.608.0E-1472103IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.002577101IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.9777106IPR007087Zinc finger, C2H2
PROSITE patternPS00028079101IPR007087Zinc finger, C2H2
SuperFamilySSF576672.14E-880130No hitNo description
Gene3DG3DSA:3.30.160.603.5E-14104126IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0024106130IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015713.921106135IPR007087Zinc finger, C2H2
PROSITE patternPS000280108130IPR007087Zinc finger, C2H2
SuperFamilySSF576672.77E-14117169No hitNo description
Gene3DG3DSA:3.30.160.602.0E-20127162IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003551.7E-4136160IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.882136165IPR007087Zinc finger, C2H2
PROSITE patternPS000280138160IPR007087Zinc finger, C2H2
SuperFamilySSF576678.07E-5160194No hitNo description
Gene3DG3DSA:3.30.160.602.9E-8163190IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0097166190IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.408166195IPR007087Zinc finger, C2H2
PROSITE patternPS000280168191IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.604.6E-9224253IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576673.22E-5227253No hitNo description
SMARTSM003550.0031230255IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.014230260IPR007087Zinc finger, C2H2
PROSITE patternPS000280232255IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 374 aa     Download sequence    Send to blast
MESQFHQNSS ERRPTFRSKT PAVKWFKEWV PQDVVATGGR CSLMKWVTAD TLKALNEKSR  60
KTVAPEPEPE PTTEVLFLCS YDGCGKTFID AGALRKHSHV HGEKQYVCHY EGCGKKFLDS  120
SKLKRHFLIH TGERDYVCPH EGCGKAFSLD FNLRSHMKTH SQENYHICPY PDCGKRYAHE  180
YKLKNHIVAH HEKMPIDEPV SVPKYATPPA EKQIRTPKPP YSNASLDRPY ACPYDGCNKA  240
YIHEYKLKLH LRREHPGHVS DENAENPANN AHNEMDEASD QDAYAGKRVN GKSQKQNRPK  300
PNLKYPPAKV AQRKGSAPSP APMNTMKKPW PIKEDVYDEE DSEETEEDRD NVEDGWRYGE  360
NNDDDDEETE DED*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C3e-34791908119PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPbr026560.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009355278.10.0PREDICTED: uncharacterized zinc finger protein At4g06634 isoform X1
SwissprotQ2V3L31e-159YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A498J9V10.0A0A498J9V1_MALDO; Uncharacterized protein
STRINGXP_009355279.10.0(Pyrus x bretschneideri)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF56493354
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.11e-148C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]