PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Pbr027398.1

Organism

Pyrus bretschneideri

Taxonomic ID

225117

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus

Family

bHLH

Protein Properties

Length: 261aa MW: 29367 Da PI: 7.8606

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pbr027398.1	genome	CPETR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	32.6	1.5e-10	67	114	3	55
HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +++ e+Er+RR+++N+ f+ Lr+llP++ + ++ a++ ++ Y+++Lq Pbr027398.1 67 QSNFEAERKRRNKLNDVFHILRTLLPNN-----TGMDRASVIGDTIAYVSKLQ 114 5789***********************9.....67999999999999999998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	13.421	64	113	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	3.66E-14	67	128	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	3.6E-8	68	114	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	8.4E-13	70	119	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.34E-9	71	118	No hit	No description
Gene3D	G3DSA:4.10.280.10	5.3E-12	71	125	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS51671	9.009	181	258	IPR002912	ACT domain
SuperFamily	SSF55021	6.59E-5	181	257	No hit	No description
CDD	cd04873	3.22E-4	182	246	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0008152	Biological Process	metabolic process
GO:0016597	Molecular Function	amino acid binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 261 aa Download sequence Send to blast
MDLYPCFICF LVSSFVLVAF FLLTCAGKRG GMNMMMTLPS LRQMRGSLVR LKSWKLSEDQ 60 RNEKVPQSNF EAERKRRNKL NDVFHILRTL LPNNTGMDRA SVIGDTIAYV SKLQRQVKEL 120 AGELELNSNG GAKETSYICG NNGNLQSEFL RQMETIIANT PENEKMEPQV EVTELDVNEF 180 SVTVLCEHKP GGFVRLMEAL DTLGLEVTYA NVTSFKTLIF NVFKVQKNDS TGKIVQADHV 240 KDSLLEITRK LSMESIIRVA *

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a crucial role in tapetum development. Required for male fertility and pollen differentiation, especially during the post-meiotic transcriptional regulation of microspore development within the developing anther (PubMed:12535353). Binds E-box regions in the AHL16/TEK promoter. {ECO:0000269\|PubMed:12535353, ECO:0000269\|PubMed:24804694}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Pbr027398.1

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009355696.1	0.0	PREDICTED: transcription factor ABORTED MICROSPORES-like
Swissprot	Q9ZVX2	2e-48	AMS_ARATH; Transcription factor ABORTED MICROSPORES
TrEMBL	A0A498JQF2	1e-170	A0A498JQF2_MALDO; Uncharacterized protein
STRING	XP_009355696.1	0.0	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF4225	32	47

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G16910.1	8e-51	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Jiang J,Zhang Z,Cao J Pollen wall development: the associated enzymes and metabolic pathways. Plant Biol (Stuttg), 2013. 15(2): p. 249-63 [PMID:23252839] Xu J, et al. ABORTED MICROSPORES Acts as a Master Regulator of Pollen Wall Formation in Arabidopsis. Plant Cell, 2014. 26(4): p. 1544-1556 [PMID:24781116] Qian H, et al. Trace concentrations of imazethapyr (IM) affect floral organs development and reproduction in Arabidopsis thaliana: IM-induced inhibition of key genes regulating anther and pollen biosynthesis. Ecotoxicology, 2015. 24(1): p. 163-71 [PMID:25348600] Xiong SX, et al. The transcription factors MS188 and AMS form a complex to activate the expression of CYP703A2 for sporopollenin biosynthesis in Arabidopsis thaliana. Plant J., 2016. 88(6): p. 936-946 [PMID:27460657] Ferguson AC, et al. Biphasic regulation of the transcription factor ABORTED MICROSPORES (AMS) is essential for tapetum and pollen development in Arabidopsis. New Phytol., 2017. 213(2): p. 778-790 [PMID:27787905] Lou Y, et al. Positive regulation of AMS by TDF1 and the formation of a TDF1-AMS complex are required for anther development in Arabidopsis thaliana. New Phytol., 2018. 217(1): p. 378-391 [PMID:28940573] Bi H,Fan W,Zhang P C4 Protein of Sweet Potato Leaf Curl Virus Regulates Brassinosteroid Signaling Pathway through Interaction with AtBIN2 and Affects Male Fertility in Arabidopsis. Front Plant Sci, 2017. 8: p. 1689 [PMID:29021807]