PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Pbr031922.1

Organism

Pyrus bretschneideri

Taxonomic ID

225117

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus

Family

WRKY

Protein Properties

Length: 603aa MW: 65203.1 Da PI: 8.3772

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Pbr031922.1	genome	CPETR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	96.8	1.4e-30	343	401	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 Dg++WrKYGqK+ kg+++pr+YYrCt+a gCpv+k+v+r+aed +++++tYeg+Hnh+ Pbr031922.1 343 TDGCQWRKYGQKMAKGNPCPRAYYRCTMAvGCPVRKQVQRCAEDRTILITTYEGNHNHP 401 7*********************************************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	1.7E-33	327	403	IPR003657	WRKY domain
SuperFamily	SSF118290	1.44E-27	335	403	IPR003657	WRKY domain
PROSITE profile	PS50811	29.677	337	403	IPR003657	WRKY domain
SMART	SM00774	1.5E-36	342	402	IPR003657	WRKY domain
Pfam	PF03106	2.6E-26	344	401	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010200	Biological Process	response to chitin
GO:0016036	Biological Process	cellular response to phosphate starvation
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0080169	Biological Process	cellular response to boron-containing substance deprivation
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 603 aa Download sequence Send to blast
MDKGWGLTLD SDSFGFLLNK PPTAAVKLDH RHNNNKRNSF FGGERMRRRE EQTASQPSND 60 NDRMVVDEVD FFSDRKNKLK SNSTDDHHQD WSSNDAMSVK KENWTGLDVN TGLHLVTANT 120 GSDQSMVDDG ISSGRADNKR AKNHELAQLQ VELQRMNVEN QRLKEMLGQV TNNYSALQMH 180 LAAVVQQQHN RTTAAPADQS SQLHHDQNAE AKADQGKKQV LVPRQFLNLG PRATTETTDD 240 QVSNSSSEAK TRSASPPQNI NEVASPKNGQ IGPLDPVNSN TFRDGKRVGR DESPESESQG 300 WVPDKVPKLN NSAAPKPIDQ STEATMRKAR VSVRARSEAS MITDGCQWRK YGQKMAKGNP 360 CPRAYYRCTM AVGCPVRKQV QRCAEDRTIL ITTYEGNHNH PLPPAAMAMA STTTAAVSML 420 LSGSMSSADG MNMNPNNLLA RAILPCSSSV ATISASAPFP TVTLDLTTTP SQVQRPNTPF 480 QVPNFPGQPP SFGAASQQLP QIFGQALYNQ SKFSELQLSQ DVMGSTSSQQ QMQQTQSSSF 540 ADTVSAITAD PSFTAALAAA ITSIIGGGAH PSNTTTNSAS PISNNSSGAN NNNNKISSFP 600 GN*

Sequence ? help Back to Top

Protein Sequence Length: 603 aa Download sequence Send to blast

MDKGWGLTLD SDSFGFLLNK PPTAAVKLDH RHNNNKRNSF FGGERMRRRE EQTASQPSND  60
NDRMVVDEVD FFSDRKNKLK SNSTDDHHQD WSSNDAMSVK KENWTGLDVN TGLHLVTANT  120
GSDQSMVDDG ISSGRADNKR AKNHELAQLQ VELQRMNVEN QRLKEMLGQV TNNYSALQMH  180
LAAVVQQQHN RTTAAPADQS SQLHHDQNAE AKADQGKKQV LVPRQFLNLG PRATTETTDD  240
QVSNSSSEAK TRSASPPQNI NEVASPKNGQ IGPLDPVNSN TFRDGKRVGR DESPESESQG  300
WVPDKVPKLN NSAAPKPIDQ STEATMRKAR VSVRARSEAS MITDGCQWRK YGQKMAKGNP  360
CPRAYYRCTM AVGCPVRKQV QRCAEDRTIL ITTYEGNHNH PLPPAAMAMA STTTAAVSML  420
LSGSMSSADG MNMNPNNLLA RAILPCSSSV ATISASAPFP TVTLDLTTTP SQVQRPNTPF  480
QVPNFPGQPP SFGAASQQLP QIFGQALYNQ SKFSELQLSQ DVMGSTSSQQ QMQQTQSSSF  540
ADTVSAITAD PSFTAALAAA ITSIIGGGAH PSNTTTNSAS PISNNSSGAN NNNNKISSFP  600
GN*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	4e-22	329	405	1	76	WRKY transcription factor 1
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	36	47	RNSFFGGERMRR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the control of processes related to senescence and pathogen defense (PubMed:12000796). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:12000796). Activates the transcription of the SIRK gene and represses its own expression and that of the WRKY42 genes (PubMed:12000796). Modulates phosphate homeostasis and Pi translocation by regulating PHO1 expression (PubMed:25733771). {ECO:0000269\|PubMed:12000796, ECO:0000269\|PubMed:25733771}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00209	DAP	Transfer from AT1G62300	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Pbr031922.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salicylic acid, ethylene, jasmonic acid, pathogens, wounding and strongly during leaf senescence. {ECO:0000269\|PubMed:11449049, ECO:0000269\|PubMed:11722756}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	-	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	JX112905	0.0	JX112905.1 Malus hupehensis WRKY transcription factor 42 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009357474.1	0.0	PREDICTED: probable WRKY transcription factor 31
Swissprot	Q9C519	1e-161	WRKY6_ARATH; WRKY transcription factor 6
TrEMBL	A0A498IWR5	0.0	A0A498IWR5_MALDO; Uncharacterized protein
STRING	XP_009357474.1	0.0	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF866	34	121

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G62300.1	1e-140	WRKY family protein

Publications ? help Back to Top
Zhou F, et al. High humidity suppresses ssi4-mediated cell death and disease resistance upstream of MAP kinase activation, H2O2 production and defense gene expression. Plant J., 2004. 39(6): p. 920-32 [PMID:15341634] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P An extracellular subtilase switch for immune priming in Arabidopsis. PLoS Pathog., 2013. 9(6): p. e1003445 [PMID:23818851] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Singh V,Roy S,Singh D,Nandi AK Arabidopsis flowering locus D influences systemic-acquired-resistance- induced expression and histone modifications of WRKY genes. J. Biosci., 2014. 39(1): p. 119-26 [PMID:24499796] Ali MA,Wieczorek K,Kreil DP,Bohlmann H The beet cyst nematode Heterodera schachtii modulates the expression of WRKY transcription factors in syncytia to favour its development in Arabidopsis roots. PLoS ONE, 2014. 9(7): p. e102360 [PMID:25033038] Chai J,Liu J,Zhou J,Xing D Mitogen-activated protein kinase 6 regulates NPR1 gene expression and activation during leaf senescence induced by salicylic acid. J. Exp. Bot., 2014. 65(22): p. 6513-28 [PMID:25210078] Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress. Plant Cell, 2014. 26(12): p. 4656-79 [PMID:25549671] Xiao D, et al. SENESCENCE-SUPPRESSED PROTEIN PHOSPHATASE Directly Interacts with the Cytoplasmic Domain of SENESCENCE-ASSOCIATED RECEPTOR-LIKE KINASE and Negatively Regulates Leaf Senescence in Arabidopsis. Plant Physiol., 2015. 169(2): p. 1275-91 [PMID:26304848] Bakshi M, et al. WRKY6 restricts Piriformospora indica-stimulated and phosphate-induced root development in Arabidopsis. BMC Plant Biol., 2015. 15: p. 305 [PMID:26718529] Huang Y,Feng CZ,Ye Q,Wu WH,Chen YF Arabidopsis WRKY6 Transcription Factor Acts as a Positive Regulator of Abscisic Acid Signaling during Seed Germination and Early Seedling Development. PLoS Genet., 2016. 12(2): p. e1005833 [PMID:26829043] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P Correction: An Extracellular Subtilase Switch for Immune Priming in Arabidopsis. PLoS Pathog., 2016. 12(11): p. e1006003 [PMID:27806116] Li H, et al. BZR1 Positively Regulates Freezing Tolerance via CBF-Dependent and CBF-Independent Pathways in Arabidopsis. Mol Plant, 2017. 10(4): p. 545-559 [PMID:28089951] Stetter MG,Benz M,Ludewig U Increased root hair density by loss of WRKY6 in Arabidopsis thaliana. PeerJ, 2017. 5: p. e2891 [PMID:28149680] Zhou X, et al. StMYB44 negatively regulates phosphate transport by suppressing expression of PHOSPHATE1 in potato. J. Exp. Bot., 2017. 68(5): p. 1265-1281 [PMID:28338870] Bakshi M, et al. Piriformospora indica Reprograms Gene Expression in Arabidopsis Phosphate Metabolism Mutants But Does Not Compensate for Phosphate Limitation. Front Microbiol, 2017. 8: p. 1262 [PMID:28747898] Zhang Y, et al. DELLA proteins negatively regulate dark-induced senescence and chlorophyll degradation in Arabidopsis through interaction with the transcription factor WRKY6. Plant Cell Rep., 2018. 37(7): p. 981-992 [PMID:29574486]