PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pbr039920.1
Organism
Pyrus bretschneideri
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Pyrus
Family C2H2
Protein Properties Length: 236aa    MW: 27339.1 Da    PI: 7.6881
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pbr039920.1genomeCPETRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H211.30.0011537323
                 ET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2  3 Cp..dCgksFsrksnLkrHirtH 23
                 C+   Cgk F +   L++H   H
  Pbr039920.1 15 CSydSCGKIFIDAGALRKHADIH 37
                 77779**************9877 PP
2zf-C2H223.21.7e-0778102123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  y+Cp   Cgk Fs+ + L+ H++tH
  Pbr039920.1  78 YVCPreGCGKAFSQEYFLMYHMKTH 102
                  99**********************9 PP
3zf-C2H211.40.001176195523
                  TTTEEESSHHHHHHHHHH.T CS
      zf-C2H2   5 dCgksFsrksnLkrHirt.H 23 
                   C+k++ + + LkrH r  H
  Pbr039920.1 176 GCNKTYIHEDKLKRHYRAvH 195
                  7***************9888 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.605.1E-91238IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.141337IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.4711342IPR007087Zinc finger, C2H2
PROSITE patternPS0002801537IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.609.2E-54170IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM00355134272IPR015880Zinc finger, C2H2-like
SuperFamilySSF576674.17E-1459114No hitNo description
Gene3DG3DSA:3.30.160.609.1E-1571101IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015712.94478107IPR007087Zinc finger, C2H2
PfamPF000962.7E-578102IPR007087Zinc finger, C2H2
SMARTSM003555.5E-478102IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028080102IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.0E-6102129IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.34108133IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280110133IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.604.9E-7170192IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.512170200IPR007087Zinc finger, C2H2
SMARTSM003550.0016170195IPR015880Zinc finger, C2H2-like
SuperFamilySSF576678.74E-5170194No hitNo description
PROSITE patternPS000280172195IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 236 aa     Download sequence    Send to blast
MAPEPEPTNK VLFLCSYDSC GKIFIDAGAL RKHADIHAEI QHVCLYEGCG KVLFPDRKFL  60
DSSKMERHFL IHSEEKDYVC PREGCGKAFS QEYFLMYHMK THSAENYYNC PYPNCLRRYP  120
YEYKLKNHIV DYHETIDEPV CVPKYATLPA EKQIRTPKPP CGKASSDLSY ACIYDGCNKT  180
YIHEDKLKRH YRAVHPGHVF DVTRNEIDEA SDQDAYAGKR VNVKSLQNML RPNWK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C3e-22151328117PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPbr039920.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009345834.11e-170PREDICTED: uncharacterized zinc finger protein At4g06634-like
RefseqXP_009345844.11e-170PREDICTED: uncharacterized zinc finger protein At4g06634-like
SwissprotQ2V3L35e-73YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A498HU861e-137A0A498HU86_MALDO; Uncharacterized protein
STRINGXP_009345834.11e-170(Pyrus x bretschneideri)
STRINGXP_009345844.11e-170(Pyrus x bretschneideri)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF56493354
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.21e-75C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]