PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Peaxi162Scf00224g00820.1

Organism

Petunia axillaris

Taxonomic ID

33119

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Petunioideae; Petunia

Family

E2F/DP

Protein Properties

Length: 434aa MW: 47851.1 Da PI: 4.4328

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Peaxi162Scf00224g00820.1	genome	SGN	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	86.8	1.6e-27	125	190	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg Peaxi162Scf00224g00820.1 125 RYDSSLGLLTKKFINLIKQAEDGILDLNNAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 190 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	3.8E-29	123	192	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	3.54E-17	125	188	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	1.9E-34	125	190	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	1.2E-24	127	190	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	8.70E-48	201	307	No hit	No description
SuperFamily	SSF144074	3.14E-32	203	307	No hit	No description
Pfam	PF16421	8.0E-33	206	305	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 434 aa Download sequence Send to blast
MQNQHQQKQS LKPQLQFSLN KPVFGDYHRF SSDSFNQQPV PGIVVKTPPL KRKSVAANYG 60 QGVGDQNPVT GYANVNSPVQ TPVSGKAGNA QKVPRTSKAR STSQAVASNI GSPSGNNVTP 120 GGPCRYDSSL GLLTKKFINL IKQAEDGILD LNNAADTLEV QKRRIYDITN VLEGIGLIEK 180 KLKNRIQWKG LDVSKPGEAD DSVASLQAEV ENLTIEEHRV DEQIREMQEK LRDLSEDENN 240 QRWLFVTEGD IKSLPCLQNE TLIAIKAPHG TTLEVPDPDE AVDYPQRRYR IVLRSTMGPI 300 DVYLVSQFEE KFEEINADEA PPSVPSTSGL NENVTATLAT EENRVDTGME EKENQRVCSD 360 VGTSQDFVSG IMKIVPDDNE ADYWFFSDAG AAIDWNELDA IQEDYSIANV STPRSSTPPP 420 NTTEVPSEAN TTEC

Sequence ? help Back to Top

Protein Sequence Length: 434 aa Download sequence Send to blast

MQNQHQQKQS LKPQLQFSLN KPVFGDYHRF SSDSFNQQPV PGIVVKTPPL KRKSVAANYG  60
QGVGDQNPVT GYANVNSPVQ TPVSGKAGNA QKVPRTSKAR STSQAVASNI GSPSGNNVTP  120
GGPCRYDSSL GLLTKKFINL IKQAEDGILD LNNAADTLEV QKRRIYDITN VLEGIGLIEK  180
KLKNRIQWKG LDVSKPGEAD DSVASLQAEV ENLTIEEHRV DEQIREMQEK LRDLSEDENN  240
QRWLFVTEGD IKSLPCLQNE TLIAIKAPHG TTLEVPDPDE AVDYPQRRYR IVLRSTMGPI  300
DVYLVSQFEE KFEEINADEA PPSVPSTSGL NENVTATLAT EENRVDTGME EKENQRVCSD  360
VGTSQDFVSG IMKIVPDDNE ADYWFFSDAG AAIDWNELDA IQEDYSIANV STPRSSTPPP  420
NTTEVPSEAN TTEC

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	4e-28	120	191	2	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT012840	0.0	BT012840.1 Lycopersicon esculentum clone 113908F, mRNA sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006362858.1	0.0	PREDICTED: transcription factor E2FB
Swissprot	Q9FV71	1e-147	E2FB_ARATH; Transcription factor E2FB
TrEMBL	A0A0V0II58	0.0	A0A0V0II58_SOLCH; Putative transcription factor E2FB-like
STRING	XP_009802122.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1077	24	84

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G22220.2	1e-149	E2F transcription factor 1

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]