PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Peaxi162Scf00360g00314.1
Organism
Petunia axillaris
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Petunioideae; Petunia
Family C2H2
Protein Properties Length: 469aa    MW: 54077.9 Da    PI: 8.2678
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Peaxi162Scf00360g00314.1genomeSGNView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H211.30.0011203225123
                               EEETTTTEEESSHHHHHHHHHHT CS
                   zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                               + C+ C    +rk++L+rH+r++
  Peaxi162Scf00360g00314.1 203 FFCEFCLNFMKRKEQLQRHMRKC 225
                               67*******************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541606.59E-2554170IPR016197Chromo domain-like
Gene3DG3DSA:2.30.30.2705.4E-3758130No hitNo description
PfamPF117171.8E-2059118IPR025995RNA binding activity-knot of a chromodomain
CDDcd000241.22E-672118No hitNo description
SMARTSM002982.3E-673133IPR000953Chromo/chromo shadow domain
Gene3DG3DSA:2.30.30.2705.4E-37164214No hitNo description
PROSITE profilePS5172672.992169464IPR002717Histone acetyltransferase domain, MYST-type
SuperFamilySSF557297.52E-104170465IPR016181Acyl-CoA N-acyltransferase
Gene3DG3DSA:3.40.630.302.2E-65228395IPR016181Acyl-CoA N-acyltransferase
PfamPF018532.8E-76267431IPR002717Histone acetyltransferase domain, MYST-type
CDDcd043010.00262305363No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006281Biological ProcessDNA repair
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010224Biological Processresponse to UV-B
GO:2000028Biological Processregulation of photoperiodism, flowering
GO:0005634Cellular Componentnucleus
GO:0043995Molecular Functionhistone acetyltransferase activity (H4-K5 specific)
Sequence ? help Back to Top
Protein Sequence    Length: 469 aa     Download sequence    Send to blast
MGSIDTPSRA ESPINGTAKS NGQPAAGDHQ PPVAVETNGA ANEPLRKSRK GSGGGVLPLE  60
VGTRVMCRWR DGKYHPVKVI ERRKFSGDGG VTEYEYYVHY TEFNRRLDEW VKLEQLDLNS  120
VETVVDEKVE DKVTSLKMTR HQKRKIDETH VEGHEELDAA SLREHEEFTK VKNIATIELG  180
RYEIETWYFS PFPPEYNDCS KLFFCEFCLN FMKRKEQLQR HMRKCDLKHP PGDEIYRSGT  240
LSMFERKTLW QCVYRYLSYK ISSVGPLLQV DGKKNKVYGQ NLCYLAKLFL DHKTLYYDVD  300
LFLFYVLCEC DDRGCHMVGY FSKEKHSEES YNLACILTLP PYQRKGYGKF LIAFSYELSK  360
KEGKVGTPER PLSDLGMLSY RGYWTRVLLD ILKKHKGNIS IKELSDMTAI KAEDILSTLQ  420
GLELIQYRKG QHVICADPKV LDRHLKAAGR GGLEVDVSKL IWTPYKEQN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4dnc_A1e-1121654691283Histone acetyltransferase KAT8
4dnc_B1e-1121654691283Histone acetyltransferase KAT8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtHistone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac) (PubMed:17877703, PubMed:19040736, PubMed:22170978, PubMed:23273925). Essential for gametophyte development (PubMed:19040736). Involved in DNA repair after UV-B exposure (PubMed:22170978). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925). {ECO:0000269|PubMed:17877703, ECO:0000269|PubMed:19040736, ECO:0000269|PubMed:22170978, ECO:0000269|PubMed:23273925}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated upon UV-B exposure. {ECO:0000269|PubMed:22170978}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY3464580.0AY346458.1 Solanum chacoense MYST-type acetyltransferase mRNA, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016569865.10.0PREDICTED: histone acetyltransferase of the MYST family 1-like
SwissprotQ9FLF70.0MYST1_ARATH; Histone acetyltransferase of the MYST family 1
TrEMBLA0A1U8GFG30.0A0A1U8GFG3_CAPAN; Histone acetyltransferase
TrEMBLA0A2G2WXV50.0A0A2G2WXV5_CAPBA; Histone acetyltransferase
TrEMBLA0A2G3CMD10.0A0A2G3CMD1_CAPCH; Histone acetyltransferase
STRINGXP_009601252.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA439133
Publications ? help Back to Top
  1. Latrasse D, et al.
    The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis.
    BMC Plant Biol., 2008. 8: p. 121
    [PMID:19040736]
  2. Campi M,D'Andrea L,Emiliani J,Casati P
    Participation of chromatin-remodeling proteins in the repair of ultraviolet-B-damaged DNA.
    Plant Physiol., 2012. 158(2): p. 981-95
    [PMID:22170978]
  3. Bari A,Orazova S,Ivashchenko A
    miR156- and miR171-binding sites in the protein-coding sequences of several plant genes.
    Biomed Res Int, 2013. 2013: p. 307145
    [PMID:23936788]
  4. Xu Y, et al.
    Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes.
    Nucleic Acids Res., 2014. 42(17): p. 10960-74
    [PMID:25183522]
  5. Raevsky AV,Sharifi M,Samofalova DA,Karpov PA,Blume YB
    3D structure prediction of histone acetyltransferase proteins of the MYST family and their interactome in Arabidopsis thaliana.
    J Mol Model, 2016. 22(11): p. 256
    [PMID:27709438]
  6. Fina JP,Masotti F,Rius SP,Crevacuore F,Casati P
    HAC1 and HAF1 Histone Acetyltransferases Have Different Roles in UV-B Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1179
    [PMID:28740501]