PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Pgl005893

Organism

Picea glauca

Taxonomic ID

3330

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Acrogymnospermae; Pinidae; Pinales; Pinaceae; Picea

Family

Whirly

Protein Properties

Length: 266aa MW: 29427.7 Da PI: 8.1962

Description

Whirly family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Pgl#S24989685	PU_unref	Unigene	View CDS
PUT-175a-Picea_glauca-10622	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Whirly	166.5	6.9e-52	85	222	2	139
Whirly 2 vyktkaalkvkavrptfealdsgnlklkraGglllelanataerkydWekkqsfalsatevaelvdlaskesceffhdpaakgsneGkvrkalkvePlpd 101 yk+k+al +++++p+++++dsg ++l+++G ++le+a+a++ r+ydW+kkq fals+ e+++l++l ++e+ceffhdp+ ++s++Gk+rk+lkv l d Pgl005893 85 FYKGKTALGMQPKAPEYSTVDSGGIRLSKEGCVFLEFAPAVGIRQYDWSKKQIFALSVLELGTLLSLDPNEPCEFFHDPFVGKSEAGKIRKVLKVGMLQD 184 6************************************************************************************************* PP Whirly 102 GsGlfvnlsvtnslvkgnesfsvPvskaefavlrsllv 139 G+f+nl v+ ++ +es+ +P++k+ef+v++s+++ Pgl005893 185 TGGYFFNLRVSDRNLNIDESLFMPITKGEFSVMQSAFN 222 *********************************996 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.30.31.10	6.5E-68	74	244	IPR009044	ssDNA-binding transcriptional regulator
SuperFamily	SSF54447	2.43E-59	77	260	IPR009044	ssDNA-binding transcriptional regulator
Pfam	PF08536	8.8E-51	86	220	IPR013742	Plant transcription factor

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 266 aa Download sequence Send to blast
TLLATLTPIP VLKFGAQAEL NAPPPLRPAL QQQQQEEKNA KVVKASLNDE SSQTHIFSSS 60 PDRSALAQPG LLRGQSSKIF VKYTFYKGKT ALGMQPKAPE YSTVDSGGIR LSKEGCVFLE 120 FAPAVGIRQY DWSKKQIFAL SVLELGTLLS LDPNEPCEFF HDPFVGKSEA GKIRKVLKVG 180 MLQDTGGYFF NLRVSDRNLN IDESLFMPIT KGEFSVMQSA FNFILPYLMG WHAYIDSTKL 240 NESGHFTSGS PSIGKRPDLE WGDVPF

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4koo_A	2e-72	71	239	1	169	Single-stranded DNA-binding protein WHY1, chloroplastic
4koo_B	2e-72	71	239	1	169	Single-stranded DNA-binding protein WHY1, chloroplastic
4koo_C	2e-72	71	239	1	169	Single-stranded DNA-binding protein WHY1, chloroplastic
4koo_D	2e-72	71	239	1	169	Single-stranded DNA-binding protein WHY1, chloroplastic
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Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Pgl.2585	0.0	vegetative bud

Functional Description ? help Back to Top
Source	Description
UniProt	Single-stranded DNA-binding protein that functions in both chloroplasts and nucleus. In chloroplasts, maintains plastid genome stability by preventing break-induced and short homology-dependent illegitimate recombinations. In nucleus, modulates telomere length homeostasis by inhibiting the action of the telomerase at the extreme termini of chromosomes. Is recruited to a distal element upstream of the kinesin KP1 to mediate the transcriptional repression of KP1. Is required for full salicylic acid-dependent plant disease resistance responses. Can bind double-stranded DNA in vivo. {ECO:0000269\|PubMed:14960277, ECO:0000269\|PubMed:17217467, ECO:0000269\|PubMed:19666500, ECO:0000269\|PubMed:19669906, ECO:0000269\|PubMed:20551348, ECO:0000269\|PubMed:21911368}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salicylic acid (SA) and infection by H.parasitica. {ECO:0000269\|PubMed:14960277, ECO:0000269\|PubMed:19669906}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010256524.1	4e-77	PREDICTED: single-stranded DNA-binding protein WHY1, chloroplastic-like
Swissprot	Q9M9S3	5e-76	WHY1_ARATH; Single-stranded DNA-binding protein WHY1, chloroplastic
TrEMBL	A9NQE8	1e-114	A9NQE8_PICSI; Uncharacterized protein
STRING	XP_010256524.1	1e-76	(Nelumbo nucifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G14410.1	4e-70	ssDNA-binding transcriptional regulator

Publications ? help Back to Top
Lepage É,Zampini É,Brisson N Plastid genome instability leads to reactive oxygen species production and plastid-to-nucleus retrograde signaling in Arabidopsis. Plant Physiol., 2013. 163(2): p. 867-81 [PMID:23969600] Carella P,Wilson DC,Cameron RK Some things get better with age: differences in salicylic acid accumulation and defense signaling in young and mature Arabidopsis. Front Plant Sci, 2014. 5: p. 775 [PMID:25620972] Zampini É,Lepage É,Tremblay-Belzile S,Truche S,Brisson N Organelle DNA rearrangement mapping reveals U-turn-like inversions as a major source of genomic instability in Arabidopsis and humans. Genome Res., 2015. 25(5): p. 645-54 [PMID:25800675] Ren Y,Li Y,Jiang Y,Wu B,Miao Y Phosphorylation of WHIRLY1 by CIPK14 Shifts Its Localization and Dual Functions in Arabidopsis. Mol Plant, 2017. 10(5): p. 749-763 [PMID:28412544] Karpinska B,Alomrani SO,Foyer CH Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling. Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018. [PMID:28808105] Huang D,Lin W,Deng B,Ren Y,Miao Y Dual-Located WHIRLY1 Interacting with LHCA1 Alters Photochemical Activities of Photosystem I and Is Involved in Light Adaptation in Arabidopsis. Int J Mol Sci, 2018. [PMID:29112140] Guan Z,Wang W,Yu X,Lin W,Miao Y Comparative Proteomic Analysis of Coregulation of CIPK14 and WHIRLY1/3 Mediated Pale Yellowing of Leaves in Arabidopsis. Int J Mol Sci, 2018. [PMID:30065159]