PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pgl009067
Organism
Picea glauca
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Acrogymnospermae; Pinidae; Pinales; Pinaceae; Picea
Family C2H2
Protein Properties Length: 534aa    MW: 61602.5 Da    PI: 8.48
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Pgl#S55336729PU_unrefUnigeneView CDS
PUT-175a-Picea_glauca-2250PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H211.60.00085293315123
                EEETTTTEEESSHHHHHHHHHHT CS
    zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                y C+ C    +rk++L+rH+r++
  Pgl009067 293 YFCEFCLNFMKRKEQLQRHMRKC 315
                78*******************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541605.59E-22147260IPR016197Chromo domain-like
Gene3DG3DSA:2.30.30.2701.1E-37149220No hitNo description
PfamPF117171.0E-20150207IPR025995RNA binding activity-knot of a chromodomain
CDDcd000241.93E-7163209No hitNo description
SMARTSM002986.0E-7164223IPR000953Chromo/chromo shadow domain
Gene3DG3DSA:2.30.30.2701.1E-37254304No hitNo description
PROSITE profilePS5172675.699259530IPR002717Histone acetyltransferase domain, MYST-type
SuperFamilySSF557292.24E-111260531IPR016181Acyl-CoA N-acyltransferase
Gene3DG3DSA:3.40.630.305.5E-73318461IPR016181Acyl-CoA N-acyltransferase
PfamPF018533.4E-84320497IPR002717Histone acetyltransferase domain, MYST-type
CDDcd043010.00222371429No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0016747Molecular Functiontransferase activity, transferring acyl groups other than amino-acyl groups
Sequence ? help Back to Top
Protein Sequence    Length: 534 aa     Download sequence    Send to blast
RGRFGLLKAN ISGKTKPDWY TDDQVQGVIY TTSTYEHLQR ASGRLTIAAA ASLISMLKQQ  60
QQQQKKKTGL ENSVDKMGMG SADESGRFST SNGQFMNMNN GVIKEEWKGG VPVVPPAPTT  120
VPVITNVKVE TPSSPDHDLV RKRKLGFLPL EVGTRVLCKW RDGKFHPVKI IERRKLPNGT  180
TNDYEYYVHY TEFNRRLDEW VKLEQLELDS VETDADEKVD DKAGSLKMTR HQKRKIDETH  240
VEGNEELDAA SLREHEEFTK VKNITKIELG RYEIETWYFS PFPAEYNSCE KLYFCEFCLN  300
FMKRKEQLQR HMRKCDLKHP PGDEIYRSGT LSMFEVDGKK NKVYAQNLCY LAKLFLDHKT  360
LYYDVDLFLF YILCECDDRG CHMVGYFSKE KHSEESYNLA CILTLPPYQR KGYGKFLISF  420
SYELSKKEGK VGTPERPLSD LGLLSYRGYW TRVLLDILKK HKNNISIKEL SDMTAIKAED  480
VLSTLQGLDL IQYRKGQHAI CADPKVLDRH LKAVGRGGLE VDVCKLIWTP YKEQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4dnc_A1e-1162555341282Histone acetyltransferase KAT8
4dnc_B1e-1162555341282Histone acetyltransferase KAT8
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Pgl.154370.0needle| stem
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in cotyledons, leaves, stems, roots and, at higher levels in developing flowers, particularly in the anthers and gynoecia (PubMed:19040736). Constitutively expressed in all tissues, predominantly in shoot apical meristem (PubMed:23273925). {ECO:0000269|PubMed:19040736, ECO:0000269|PubMed:23273925}.
Functional Description ? help Back to Top
Source Description
UniProtHistone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac) (PubMed:17877703, PubMed:19040736, PubMed:22170978, PubMed:23273925). Essential for gametophyte development (PubMed:19040736). Involved in DNA repair after UV-B exposure (PubMed:22170978). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925). {ECO:0000269|PubMed:17877703, ECO:0000269|PubMed:19040736, ECO:0000269|PubMed:22170978, ECO:0000269|PubMed:23273925}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated upon UV-B exposure. {ECO:0000269|PubMed:22170978}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010261128.10.0PREDICTED: histone acetyltransferase of the MYST family 1-like isoform X1
SwissprotQ9FLF70.0MYST1_ARATH; Histone acetyltransferase of the MYST family 1
TrEMBLA9NUX90.0A9NUX9_PICSI; Histone acetyltransferase
STRINGXP_010261128.10.0(Nelumbo nucifera)
Publications ? help Back to Top
  1. Latrasse D, et al.
    The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis.
    BMC Plant Biol., 2008. 8: p. 121
    [PMID:19040736]
  2. Campi M,D'Andrea L,Emiliani J,Casati P
    Participation of chromatin-remodeling proteins in the repair of ultraviolet-B-damaged DNA.
    Plant Physiol., 2012. 158(2): p. 981-95
    [PMID:22170978]
  3. Bari A,Orazova S,Ivashchenko A
    miR156- and miR171-binding sites in the protein-coding sequences of several plant genes.
    Biomed Res Int, 2013. 2013: p. 307145
    [PMID:23936788]
  4. Xu Y, et al.
    Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes.
    Nucleic Acids Res., 2014. 42(17): p. 10960-74
    [PMID:25183522]
  5. Raevsky AV,Sharifi M,Samofalova DA,Karpov PA,Blume YB
    3D structure prediction of histone acetyltransferase proteins of the MYST family and their interactome in Arabidopsis thaliana.
    J Mol Model, 2016. 22(11): p. 256
    [PMID:27709438]
  6. Fina JP,Masotti F,Rius SP,Crevacuore F,Casati P
    HAC1 and HAF1 Histone Acetyltransferases Have Different Roles in UV-B Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1179
    [PMID:28740501]