PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pgl009273
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Acrogymnospermae; Pinidae; Pinales; Pinaceae; Picea
Family SBP
Protein Properties Length: 486aa    MW: 54554.9 Da    PI: 5.9785
Description SBP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PUT-175a-Picea_glauca-7918PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SBP115.23.6e-36130206177
                --SSTT-----TT--HHHHHTT--HHHHT-S-EEETTEEEEE-TTTSSEEETTT--SS--S-STTTT-------S-- CS
        SBP   1 lCqvegCeadlseakeyhrrhkvCevhskapvvlvsgleqrfCqqCsrfhelsefDeekrsCrrrLakhnerrrkkq 77 
                +Cqv++Cead+s++k yhrrh+vC  +++a++v+++++ qr+CqqC++fh l++fDe+krsCrr+L++hn+rrr+k 
  Pgl009273 130 RCQVPSCEADISHLKGYHRRHRVCLCCANAATVVLDDVPQRYCQQCGKFHLLTDFDEGKRSCRRKLERHNNRRRRKP 206
                6************************************************************************9975 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:4.10.1100.101.3E-26128192IPR004333Transcription factor, SBP-box
PROSITE profilePS5114128.872128205IPR004333Transcription factor, SBP-box
SuperFamilySSF1036121.06E-32129210IPR004333Transcription factor, SBP-box
PfamPF031105.8E-26131205IPR004333Transcription factor, SBP-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 486 aa     Download sequence    Send to blast
MADLLDDSVA SVLDAGDWEW DSVLDFSIGS LPHILPWQSE ELSDDLSERL LPSQVLEVNQ  60
AREVQNASPR NRSQDAEEEE KAAASSRIRK RDPRLICSNF LAGRVPCACP EMDNMEEELS  120
RKRAKVVVLR CQVPSCEADI SHLKGYHRRH RVCLCCANAA TVVLDDVPQR YCQQCGKFHL  180
LTDFDEGKRS CRRKLERHNN RRRRKPVNVV EASVQEQTLR AESALQSADT EPHNNGKSGQ  240
ASKSFSYPGC GEKQSSSGSE ERNISEVEQP YKGDSSLKNV GSRSDDVSKI SSSSMPVKVS  300
TELEGKRFPE RDIGSGEKFD DEDVRVVENS RAIMLVGPRS GDNGSTYAEL NEQSYTGMPI  360
EENSHKDRFP HNISGRSEKD EGAGPLKSSL SSNRHDKHFS YTSVCPTGRI SFKLYDWNPA  420
EFPRRLRQQI LQWLADMPIE LEGYIRPGCT ILTAFIALPQ FMWEKLFANS PGYIHSLLNG  480
SESILS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ul5_A1e-39128208383squamosa promoter binding protein-like 7
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1191203RRKLERHNNRRRR
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed constitutively during plant development. {ECO:0000269|PubMed:10524240}.
UniprotTISSUE SPECIFICITY: Expressed in roots rosette leaves, cauline leaves, stems, flowers and siliques. {ECO:0000269|PubMed:24335506}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that participates in reprogramming global gene expression during copper deficiency in order to improve the metal uptake and prioritize its distribution to copper proteins of major importance (Probable). Binds directly to 5'-GTAC-3' motifs in the microRNA (miRNA) promoter of the stress-responsive miRNAs miR398b and miR398c to activate their transcription. During copper deficiency, activates the copper transporters COPT1 and COPT2, and the copper chaperone CCH, directly or indirectly via miRNAs. Required for the expression of the miRNAs miR397, miR408 and miR857 (PubMed:19122104). Acts coordinately with HY5 to regulate miR408 and its target genes in response to changes in light and copper conditions (PubMed:25516599). Activates miR857 and its target genes in response to low copper conditions (PubMed:26511915). Involved in cadmium stress response by regulating miR397a, miR398b, miR398c and miR857 (PubMed:27352843). Required for iron homeostasis during copper deficiency (PubMed:22374396). {ECO:0000269|PubMed:19122104, ECO:0000269|PubMed:22374396, ECO:0000269|PubMed:25516599, ECO:0000269|PubMed:26511915, ECO:0000269|PubMed:27352843}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
SwissprotQ8S9G83e-56SPL7_ARATH; Squamosa promoter-binding-like protein 7
TrEMBLB8LQP10.0B8LQP1_PICSI; Uncharacterized protein
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G18830.22e-43squamosa promoter binding protein-like 7
Publications ? help Back to Top
  1. Zhang H, et al.
    MicroRNA408 is critical for the HY5-SPL7 gene network that mediates the coordinated response to light and copper.
    Plant Cell, 2014. 26(12): p. 4933-53
    [PMID:25516599]
  2. Zhao Y, et al.
    MicroRNA857 Is Involved in the Regulation of Secondary Growth of Vascular Tissues in Arabidopsis.
    Plant Physiol., 2015. 169(4): p. 2539-52
    [PMID:26511915]
  3. Perea-GarcĂ­a A, et al.
    Modulation of copper deficiency responses by diurnal and circadian rhythms in Arabidopsis thaliana.
    J. Exp. Bot., 2016. 67(1): p. 391-403
    [PMID:26516126]
  4. Gielen H,Remans T,Vangronsveld J,Cuypers A
    Toxicity responses of Cu and Cd: the involvement of miRNAs and the transcription factor SPL7.
    BMC Plant Biol., 2016. 16(1): p. 145
    [PMID:27352843]
  5. Yan J, et al.
    Arabidopsis Pollen Fertility Requires the Transcription Factors CITF1 and SPL7 That Regulate Copper Delivery to Anthers and Jasmonic Acid Synthesis.
    Plant Cell, 2017. 29(12): p. 3012-3029
    [PMID:29114014]
  6. Araki R, et al.
    SPL7 locally regulates copper-homeostasis-related genes in Arabidopsis.
    J. Plant Physiol., 2018.
    [PMID:29635212]