PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Phvul.011G097700.1
Common NamePHAVU_011G097700g
Organism
Phaseolus vulgaris
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Phaseolus
Family E2F/DP
Protein Properties Length: 453aa    MW: 49985.9 Da    PI: 4.8866
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Phvul.011G097700.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP871.4e-27144209171
             E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                         r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  Phvul.011G097700.1 144 RYDSSLGLLTKKFINLIKQAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 209
                         6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.5E-29142211IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.54E-17144207IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013728.0E-35144209IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023199.9E-25146209IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146604.27E-48220326No hitNo description
SuperFamilySSF1440741.2E-33222326No hitNo description
PfamPF164214.3E-34225324IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 453 aa     Download sequence    Send to blast
MSAPRAPSAA AATASSNPPD QIMHSMKRQL PFSSMKPPFA AAGDYHRFAP DHRPSLDAEA  60
VVVKTPQLKR KSEAADFEAD SGDRMTPGTT EPANSPFRTP VSGKTGKGGK SSRMTKCNRL  120
GTQTPGSNIG SPSGNNLTPA GPCRYDSSLG LLTKKFINLI KQAEDGILDL NKAADTLEVQ  180
KRRIYDITNV LEGIGLIEKK LKNRIQWKGL DVSRPGEADD NFASLQAEVE NLTMDERRLD  240
EQIREMQERL RELSEDENNE RMLFVTEEDI KNLPCFQNET LIAIKAPHGT TLEVPDPDEA  300
VDYPQRRYRI VLRSTMGPID VYLVSQFEEK FEDINGVDVS PKSPPSHKIK PKHQNHELGY  360
APTISEFTTS QDFVSGIMKI VPSDVASEAD YWLLSDADVS ITDMWRTEPG VEWNELDPLQ  420
EDYCITRENT STPSHPSNVG EVLSSASKPT GG*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A3e-27139210274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPhvul.011G097700.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0524550.0BT052455.1 Medicago truncatula clone MTYFD_FE_FF_FG1G-O-10 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_007132481.10.0hypothetical protein PHAVU_011G097700g
SwissprotQ9FV711e-154E2FB_ARATH; Transcription factor E2FB
TrEMBLV7AGS30.0V7AGS3_PHAVU; Uncharacterized protein
STRINGXP_007132481.10.0(Phaseolus vulgaris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19473490
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.21e-149E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]