PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Potri.015G070300.2
Common NamePOPTR_0015s08160g
Organism
Populus trichocarpa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus
Family E2F/DP
Protein Properties Length: 385aa    MW: 43191.4 Da    PI: 8.9587
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Potri.015G070300.2genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP75.26.6e-242085171
             E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                        rk+ksL+ll+++fl+l+++ + +++ l+++a++L    v  +rRRiYDi+NVLe+++++++k+kn+++wkg
  Potri.015G070300.2 20 RKQKSLGLLCTNFLTLYNRDDIDVIGLDDAASKL---GV--ERRRIYDIVNVLESVGVLARKAKNKYSWKG 85
                        79****************9999************...**..****************************98 PP
2E2F_TDP741.6e-23156236171
             E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                         r+eksL+lltq+f+kl+ +s+++ ++l+e ak L+ +      +++k+RR+YDi+NVL++l+liek     ++k+++rw g
  Potri.015G070300.2 156 RREKSLGLLTQNFVKLFVCSNANLISLDESAKLLLGDghnlsIMRTKVRRLYDIANVLSSLKLIEKthtadTRKPAFRWLG 236
                         689***************************************9***************************99*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.4E-251686IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.21E-151983IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.4E-282085IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.4E-202185IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.103.0E-22152237IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.0E-28156236IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467856.39E-12158237IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023192.7E-18158236IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 385 aa     Download sequence    Send to blast
MALSYTDIID PPSRHHAYSR KQKSLGLLCT NFLTLYNRDD IDVIGLDDAA SKLGVERRRI  60
YDIVNVLESV GVLARKAKNK YSWKGFASVP KALQDLKEEG LRDNVNTIDR QSNNSAKVAN  120
DDEDEDDDSD SNPNTGSQNE NSSIIKSMAV SRSDHRREKS LGLLTQNFVK LFVCSNANLI  180
SLDESAKLLL GDGHNLSIMR TKVRRLYDIA NVLSSLKLIE KTHTADTRKP AFRWLGFRGK  240
SENGSGDPLA PFESRKRTFG ADITNTCFKR NKMDSSVDGD KSQNLKMQQI KDENMVTVAE  300
RGNFGQDLQQ KSGSFQFGPF APVSVAKAGN PEDNVTRIYD WEGLSSTFRP QYHNQALRDL  360
FSHYTEAWKL WYTEVAGKKP LHIS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A7e-38192283228Transcription factor E2F8
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Not detected during early S phase. Expressed at both the G1/S and S/G2 transitions, with a peak during G2. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:18787127}.
UniprotTISSUE SPECIFICITY: Expressed exclusively in mitotically dividing cells. Highly expressed in young leaves and mature flowers. Lower expression in young stalk and in young and mature flowers. {ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366}.
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPotri.015G070300.2
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002321561.30.0E2F transcription factor-like E2FE
SwissprotQ8LSZ41e-130E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A2K1XJ940.0A0A2K1XJ94_POPTR; Uncharacterized protein
STRINGPOPTR_0015s08160.10.0(Populus trichocarpa)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-133DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]