PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pp3c3_11980V3.2.p
Common NameDP2
Organism
Physcomitrella patens
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Bryophyta; Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrella
Family E2F/DP
Protein Properties Length: 319aa    MW: 34892.1 Da    PI: 6.1372
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pp3c3_11980V3.2.pgenomeCOSMOSSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP81.76.2e-2641133371
            E2F_TDP   3 eksLrlltqkflklleksee.givtlnevakeLvse...........................dvknkrRRiYDilNVLealnliekkekne 66 
                        +k+Lr++++k   ++ek+e+ g++t+neva+eLv+e                           d+kn+rRR+YD+lNVL+a+++i k +k++
  Pp3c3_11980V3.2.p  41 GKGLRHFSMK---VCEKVESkGRTTYNEVADELVAEftnpdsphvspdqgadtvsvragqqqyDEKNIRRRVYDALNVLMAVGIILK-DKKD 128
                        79********...*****999******************************************************************.**** PP

            E2F_TDP  67 irwkg 71 
                        i+wkg
  Pp3c3_11980V3.2.p 129 IQWKG 133
                        ***98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.105.8E-4235138IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013728.0E-3339133IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467854.35E-1942134IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.1E-2442133IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd144581.92E-39138240IPR014889Transcription factor DP, C-terminal
SMARTSM011383.3E-53140262IPR014889Transcription factor DP, C-terminal
SuperFamilySSF1440743.66E-40140245No hitNo description
PfamPF087815.3E-35141245IPR014889Transcription factor DP, C-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042023Biological ProcessDNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 319 aa     Download sequence    Send to blast
MVSNGIDARL AHLDDPDSPD AEVIGGKKKR GGRAAGGEKG GKGLRHFSMK VCEKVESKGR  60
TTYNEVADEL VAEFTNPDSP HVSPDQGADT VSVRAGQQQY DEKNIRRRVY DALNVLMAVG  120
IILKDKKDIQ WKGFPSASID DVADLKAESM RIRGRIERKA AYLHELQSQM TGLRNLVSRN  180
ESLSQGNNSV PHVALPFILV QTRPQATVEV EISEDMQVVH FDFNSTPFEL HDDAYVLKAM  240
KLQEQPGGTC SDGMVHADFE DEIGSFEEDS PPVSGVFQRS NFPAHPSSHY ASMSGAGKNS  300
WPPVPGILKA RVKHENVS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_B2e-3433138193PROTEIN (TRANSCRIPTION FACTOR DP-2)
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Ppa.137550.0gametophore| protonema
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed during the whole cell cycle. {ECO:0000269|PubMed:11669580}.
UniprotTISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:16920782}.
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. The complex DPB/E2FC restricts cell division and lateral root initiation and may function as a negative regulator of E2F-regulated genes. The interaction with SKP2A is controlled by auxin. {ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:16920782}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB5473410.0AB547341.1 Physcomitrella patens DP;2 mRNA for DP transcription factor;2, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024372177.10.0transcription factor-like protein DPB isoform X1
SwissprotQ9FNY21e-100DPB_ARATH; Transcription factor-like protein DPB
TrEMBLG1UDG10.0G1UDG1_PHYPA; DP transcription factor2
STRINGPP1S74_252V6.10.0(Physcomitrella patens)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP25111734
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03415.12e-93Transcription factor DP