PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pp3c4_13590V3.3.p
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Bryophyta; Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrella
Family E2F/DP
Protein Properties Length: 219aa    MW: 24201.6 Da    PI: 9.352
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pp3c4_13590V3.3.pgenomeCOSMOSSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP78.75.2e-2542122471
            E2F_TDP   4 ksLrlltqkflklleksee.givtlnevakeLvse................dvknkrRRiYDilNVLealnliekkekneirwkg 71 
                         sLr++++k   ++  +e+ g++t+neva+eLv+e                d+kn+rRR+YD+lNVL+a+++i k +k++i+wkg
  Pp3c4_13590V3.3.p  42 ISLRHFSMK---VCGIVESkGRTTYNEVADELVAEfsntdfphvssdqpqyDEKNIRRRVYDALNVLMAMGIILK-DKKSIQWKG 122
                        59*******...99998888*******************************************************.*******98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.6E-4135126IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.8E-3139122IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.5E-2343122IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.77E-2043123IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM011381.8E-27126218IPR014889Transcription factor DP, C-terminal
PfamPF087814.1E-24135212IPR014889Transcription factor DP, C-terminal
SuperFamilySSF1440741.8E-26135210No hitNo description
CDDcd144586.93E-24141207IPR014889Transcription factor DP, C-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006357Biological Processregulation of transcription from RNA polymerase II promoter
GO:0042023Biological ProcessDNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0000981Molecular FunctionRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0003677Molecular FunctionDNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 219 aa     Download sequence    Send to blast
MMGNGVVAQL QHLDVPNSLG AKVVGRKKTR GGRAAGAEKG GISLRHFSMK VCGIVESKGR  60
TTYNEVADEL VAEFSNTDFP HVSSDQPQYD EKNIRRRVYD ALNVLMAMGI ILKDKKSIQW  120
KGLPSSDVGN VADLKVAGLY NLVSRNEQLS QEKKAPHRVV ALPFILVQTR PHATVELEIS  180
ENMQVVHFDF NSTPFELHDD AYVVKTLSSQ EQRTARTQ*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_B2e-3533126192PROTEIN (TRANSCRIPTION FACTOR DP-2)
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Ppa.121951e-144protonema
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed during the whole cell cycle. {ECO:0000269|PubMed:11669580}.
UniprotTISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:16920782}.
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. The complex DPB/E2FC restricts cell division and lateral root initiation and may function as a negative regulator of E2F-regulated genes. The interaction with SKP2A is controlled by auxin. {ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:16920782}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB5473401e-141AB547340.1 Physcomitrella patens DP;1 mRNA for DP transcription factor;1, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024373759.11e-163transcription factor-like protein DPB isoform X2
SwissprotQ9FNY21e-81DPB_ARATH; Transcription factor-like protein DPB
TrEMBLA0A2K1KND11e-156A0A2K1KND1_PHYPA; Uncharacterized protein
STRINGPP1S219_101V6.11e-157(Physcomitrella patens)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03415.14e-76Transcription factor DP