PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Psi005125

Organism

Picea sitchensis

Taxonomic ID

3332

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Acrogymnospermae; Pinidae; Pinales; Pinaceae; Picea

Family

bHLH

Protein Properties

Length: 179aa MW: 19928.8 Da PI: 6.2771

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Psi#S55421912	PU_unref	Unigene	View CDS
PUT-183a-Picea_sitchensis-17203	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	41.7	2.1e-13	5	47	7	54
HHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 7 erErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ErrRR+++N++++ Lr+++Pk K++ a+iL AveY+k+L Psi005125 5 MAERRRRKKLNDRLFMLRSVVPKV-----SKMDRASILGDAVEYLKEL 47 68*******************6.....5**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.135	1	47	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	9.55E-16	4	62	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	4.1E-14	4	53	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.03E-11	5	51	No hit	No description
Pfam	PF00010	5.2E-11	5	47	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	2.7E-15	5	57	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS51671	8.581	108	179	IPR002912	ACT domain
CDD	cd04873	3.53E-7	116	168	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0008152	Biological Process	metabolic process
GO:0016597	Molecular Function	amino acid binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 179 aa Download sequence Send to blast
XGNLMAERRR RKKLNDRLFM LRSVVPKVSK MDRASILGDA VEYLKELLQR INDLHIELMA 60 GSSNSKPLVP TMPDFPYRMN QESQASLLNP EVEPATVEVS TREGKALNIH MFCSKKPGLL 120 LSTMRALDEL GLDVKQAIIS CLNGFALDVF RAEQSMGGDV TAEEIKALLL HTADNEDGL

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	6	13	ERRRRKKL

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed constitutively in roots, leaves, stems, and flowers. Broad expression within stomatal cell lineages of leaf epidermis, except in mature guard-cells. {ECO:0000269\|PubMed:12679534, ECO:0000269\|PubMed:18641265}.

Functional Description ? help Back to Top
Source	Description
UniProt	Mediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA (PubMed:18641265). Functions as a dimer with SPCH during stomatal initiation (PubMed:18641265, PubMed:28507175). {ECO:0000269\|PubMed:18641265, ECO:0000269\|PubMed:28507175}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013604461.1	1e-74	PREDICTED: transcription factor SCREAM2-like
Refseq	XP_013604462.1	1e-74	PREDICTED: transcription factor SCREAM2-like
Refseq	XP_013657322.1	1e-74	transcription factor SCREAM2-like
Refseq	XP_013657324.1	1e-74	transcription factor SCREAM2-like
Refseq	XP_013657326.1	1e-74	transcription factor SCREAM2-like
Refseq	XP_020113605.1	1e-74	transcription factor ICE1-like
Swissprot	Q9LPW3	9e-74	SCRM2_ARATH; Transcription factor SCREAM2
TrEMBL	D5A934	1e-125	D5A934_PICSI; Uncharacterized protein
STRING	Bo8g065080.1	5e-74	(Brassica oleracea)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G12860.1	4e-76	bHLH family protein

Publications ? help Back to Top
Tarasov VA,Khadeeva NV,Mel'nik VA,Ezhova TA,Shestakov SV The Atlg12860 gene of Arabidopsis thaliana determines cathelicidin-like antimicrobial activity. Dokl. Biol. Sci., 2009. [PMID:19760875] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Emmerstorfer A, et al. Over-expression of ICE2 stabilizes cytochrome P450 reductase in Saccharomyces cerevisiae and Pichia pastoris. Biotechnol J, 2015. 10(4): p. 623-35 [PMID:25641738] Lee HG,Seo PJ The MYB96-HHP module integrates cold and abscisic acid signaling to activate the CBF-COR pathway in Arabidopsis. Plant J., 2015. 82(6): p. 962-77 [PMID:25912720] Raissig MT,Abrash E,Bettadapur A,Vogel JP,Bergmann DC Grasses use an alternatively wired bHLH transcription factor network to establish stomatal identity. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(29): p. 8326-31 [PMID:27382177] Fu ZW,Wang YL,Lu YT,Yuan TT Nitric oxide is involved in stomatal development by modulating the expression of stomatal regulator genes in Arabidopsis. Plant Sci., 2016. 252: p. 282-289 [PMID:27717464] de Marcos A, et al. A Mutation in the bHLH Domain of the SPCH Transcription Factor Uncovers a BR-Dependent Mechanism for Stomatal Development. Plant Physiol., 2017. 174(2): p. 823-842 [PMID:28507175]