PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Pta007932

Organism

Pinus taeda

Taxonomic ID

3352

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Acrogymnospermae; Pinidae; Pinales; Pinaceae; Pinus; Pinus

Family

C2H2

Protein Properties

Length: 323aa MW: 36979.9 Da PI: 7.1517

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-157a-Pinus_taeda-25715	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	12.5	0.00046	268	290	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 y C+ C +rk++L+rH+r++ Pta007932 268 YFCEFCLNFMKRKEQLQRHMRKC 290 78*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF54160	6.04E-10	151	199	IPR016197	Chromo domain-like
Gene3D	G3DSA:2.30.30.270	1.8E-26	154	279	No hit	No description
Pfam	PF11717	7.0E-10	155	198	IPR025995	RNA binding activity-knot of a chromodomain
PROSITE profile	PS51726	28.271	234	323	IPR002717	Histone acetyltransferase domain, MYST-type
SuperFamily	SSF55729	7.95E-30	235	323	IPR016181	Acyl-CoA N-acyltransferase
Gene3D	G3DSA:3.40.630.30	7.8E-9	293	323	IPR016181	Acyl-CoA N-acyltransferase

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0016747	Molecular Function	transferase activity, transferring acyl groups other than amino-acyl groups

Sequence ? help Back to Top
Protein Sequence Length: 323 aa Download sequence Send to blast
XAGEDWTLLK ANILKVNISE EAKLNWMYTD ARIQGFVYIY MRASAESLGQ LPIIAAATSL 60 ISTPEIAAVE KENKAPNSVD KMGMGSADES GRFSTSNGQF MNMNNGLVKE EWKGGVPVVP 120 SAPTTVPVIT NVKLETPSSP DHDMARKRKL GFLPLEVGTR VLCKWRDGKF HPVKIIERRK 180 LPNGATNDYE YYVHYTECRK LENDPPSKKK DDETHVEGNE ELDVASLREH EEFTKVKNIT 240 KIELGRYEIE TWYFSPFPSE YNNCEKLYFC EFCLNFMKRK EQLQRHMRKC DLKHPPGDEI 300 YRSGTLSMFE VDGKKNKVYA QNL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5gk9_A	3e-33	239	323	2	86	Histone acetyltransferase KAT7
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Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in cotyledons, leaves, stems, roots and, at higher levels in developing flowers, particularly in the anthers and gynoecia (PubMed:19040736). Constitutively expressed in all tissues, predominantly in shoot apical meristem (PubMed:23273925). {ECO:0000269\|PubMed:19040736, ECO:0000269\|PubMed:23273925}.

Functional Description ? help Back to Top
Source	Description
UniProt	Histone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac) (PubMed:16648464, PubMed:17877703). Essential for gametophyte development (PubMed:19040736). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925). {ECO:0000269\|PubMed:16648464, ECO:0000269\|PubMed:17877703, ECO:0000269\|PubMed:19040736, ECO:0000269\|PubMed:23273925}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated upon UV-B exposure. {ECO:0000269\|PubMed:22170978}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006399456.1	1e-100	histone acetyltransferase of the MYST family 2
Refseq	XP_013608694.1	1e-100	PREDICTED: histone acetyltransferase of the MYST family 2
Refseq	XP_022866678.1	1e-101	histone acetyltransferase of the MYST family 1-like isoform X2
Swissprot	Q9LXD7	1e-100	MYST2_ARATH; Histone acetyltransferase of the MYST family 2
TrEMBL	A9NUX9	1e-157	A9NUX9_PICSI; Histone acetyltransferase
STRING	Bo9g173870.1	1e-100	(Brassica oleracea)
STRING	XP_006399456.1	1e-100	(Eutrema salsugineum)

Publications ? help Back to Top
Kerschen A,Napoli CA,Jorgensen RA,Müller AE Effectiveness of RNA interference in transgenic plants. FEBS Lett., 2004. 566(1-3): p. 223-8 [PMID:15147899] Earley K, et al. Erasure of histone acetylation by Arabidopsis HDA6 mediates large-scale gene silencing in nucleolar dominance. Genes Dev., 2006. 20(10): p. 1283-93 [PMID:16648464] Latrasse D, et al. The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis. BMC Plant Biol., 2008. 8: p. 121 [PMID:19040736] Campi M,D'Andrea L,Emiliani J,Casati P Participation of chromatin-remodeling proteins in the repair of ultraviolet-B-damaged DNA. Plant Physiol., 2012. 158(2): p. 981-95 [PMID:22170978] Bari A,Orazova S,Ivashchenko A miR156- and miR171-binding sites in the protein-coding sequences of several plant genes. Biomed Res Int, 2013. 2013: p. 307145 [PMID:23936788] Xu Y, et al. Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes. Nucleic Acids Res., 2014. 42(17): p. 10960-74 [PMID:25183522] Falcone Ferreyra ML, et al. AtPDCD5 Plays a Role in Programmed Cell Death after UV-B Exposure in Arabidopsis. Plant Physiol., 2016. 170(4): p. 2444-60 [PMID:26884483] Raevsky AV,Sharifi M,Samofalova DA,Karpov PA,Blume YB 3D structure prediction of histone acetyltransferase proteins of the MYST family and their interactome in Arabidopsis thaliana. J Mol Model, 2016. 22(11): p. 256 [PMID:27709438] Fina JP,Masotti F,Rius SP,Crevacuore F,Casati P HAC1 and HAF1 Histone Acetyltransferases Have Different Roles in UV-B Responses in Arabidopsis. Front Plant Sci, 2017. 8: p. 1179 [PMID:28740501]