PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID RrC5810_p1
Organism
Raphanus raphanistrum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
Family E2F/DP
Protein Properties Length: 455aa    MW: 50124.6 Da    PI: 4.647
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
RrC5810_p1genomeMSUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP82.73.1e-26140205171
     E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                 r+++sL+llt+kf++l++++e+g+v+ln++a++L   +v  ++RRiYDi+NVLe+++liek  kn+i wkg
  RrC5810_p1 140 RYDSSLGLLTRKFVDLIKQAEDGMVDLNKAAETL---EV--QKRRIYDITNVLEGIDLIEKPFKNRILWKG 205
                 6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.3E-27136207IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.4E-32140205IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.18E-16140203IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.5E-22142205IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146606.87E-49218322No hitNo description
SuperFamilySSF1440748.11E-33218322No hitNo description
PfamPF164212.9E-33221320IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 455 aa     Download sequence    Send to blast
MSSGVRSSPG HSQPPPSSSS SNPVVPPIRR HLAFASTKPP FHPSDYRRFA PSYLTNNVEE  60
DAVVLRSPVQ SRKRKSMMDV VSTTSCNSNG FTSSGSTSIQ HNTPLSAKRG RVTKETHSLP  120
QTPISSSGSP ATLTPSGSCR YDSSLGLLTR KFVDLIKQAE DGMVDLNKAA ETLEVQKRRI  180
YDITNVLEGI DLIEKPFKNR ILWKGVDASR PGDVDADVSV LQAEIENLNL EEQALDNQIR  240
ETEDRLRNLS ENENNQKWLF VTEEDIKSLP GFQNQTLIAV KAPHGTTLEV PDPDEAGDLP  300
QRRYRIILRS TMGPIDVYLV SEFEETNGNI EPPACLPIAS CSGSTENHDI EALTINNTET  360
TIEHQISQDH AHAQPGDTSD LNFFQEQVGG MHKITPSHIE NDDTDYWLLS NAEISMTDIW  420
NTDSGIDWDY GIADVSTPPP VMGEIAPAAI DSKPR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A2e-21135206274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
17075SRKRKS
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00661PBMTransfer from Pp3c1_6880Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF2425820.0AF242582.1 Arabidopsis thaliana E2F transcription factor-3 E2F3 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018475572.10.0PREDICTED: transcription factor E2FA-like isoform X1
SwissprotQ9FNY00.0E2FA_ARATH; Transcription factor E2FA
TrEMBLM4E2P60.0M4E2P6_BRARP; Uncharacterized protein
STRINGBra023047.1-P0.0(Brassica rapa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM80828121
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.10.0E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]