PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID RrC8715_p2
Organism
Raphanus raphanistrum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
Family E2F/DP
Protein Properties Length: 65aa    MW: 7639.9 Da    PI: 10.2289
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
RrC8715_p2genomeMSUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP37.53.8e-125394170
     E2F_TDP 41 nkrRRiYDilNVLealnliek.....kekneirwk 70
                 + RR+YDi+NVL++lnliek     ++k++++w 
  RrC8715_p2  5 VRLRRLYDIANVLSSLNLIEKaltldSRKPAFKWL 39
                4679*********************99*******5 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF467855.44E-7339IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023193.5E-10339IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.2E-10539IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 65 aa     Download sequence    Send to blast
MRTKVRLRRL YDIANVLSSL NLIEKALTLD SRKPAFKWLE YIGGPTFTFS SDLMQAEIKE  60
KSYRE
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013604540.15e-23PREDICTED: E2F transcription factor-like E2FE
RefseqXP_013705066.16e-23E2F transcription factor-like E2FE isoform X1
RefseqXP_013737731.27e-23E2F transcription factor-like E2FE
RefseqXP_018515445.16e-23PREDICTED: E2F transcription factor-like E2FE
RefseqXP_022567818.16e-23E2F transcription factor-like E2FE isoform X2
RefseqXP_022567819.16e-23E2F transcription factor-like E2FE isoform X3
SwissprotQ8LSZ43e-23E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A078HES42e-22A0A078HES4_BRANA; BnaA06g16850D protein
STRINGBra018080.1-P2e-22(Brassica rapa)
STRINGBo8g076700.12e-22(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM63042743
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.19e-26DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]