PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Rsa1.0_00992.1_g00001.1
Organism
Raphanus sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
Family E2F/DP
Protein Properties Length: 214aa    MW: 24111.5 Da    PI: 8.3251
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Rsa1.0_00992.1_g00001.1genomeRGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP42.21.4e-13401091470
                  E2F_TDP  14 lkllekseegiv.tlnevakeLvse.......dvknkrRRiYDilNVLealnliek.....kekneirwk 70 
                              ++l ++ +++iv +l+e++k L+ +        +k + RR+YDi+NVL++lnliek     ++k++++w 
  Rsa1.0_00992.1_g00001.1  40 VRLAKRLSARIVsSLDEATKLLLVDahntsimRTKVRLRRLYDIANVLSSLNLIEKahtldSRKPAFKWL 109
                              456666666444279*******9999****885555889*******************99999******5 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM013723.5E-1236110IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.04E-838109IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023197.2E-1239109IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.103.7E-1251109IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 214 aa     Download sequence    Send to blast
PCFLQSTESG VFTSVTSSSM IIVSSSEDMH VCILTASICV RLAKRLSARI VSSLDEATKL  60
LLVDAHNTSI MRTKVRLRRL YDIANVLSSL NLIEKAHTLD SRKPAFKWLE YNGGPTFTFS  120
SDLMQAETKE RVFGTDLRNV NVNRTKTKEN VTEEAVDDKN MQWQSYYDKS IDVHVSRHGP  180
RGYEFGPFAP VTGTYPHNLQ VSDIKMQIAQ PLCF
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapRsa1.0_00992.1_g00001.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006404291.17e-68E2F transcription factor-like E2FE
SwissprotQ8LSZ48e-61E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLE4MXF02e-66E4MXF0_EUTHA; mRNA, clone: RTFL01-26-N13
TrEMBLV4LPM22e-66V4LPM2_EUTSA; Uncharacterized protein
STRINGXP_006404291.13e-67(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM63042743
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.12e-63DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]