PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Rsa1.0_05242.1_g00003.1

Organism

Raphanus sativus

Taxonomic ID

3726

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus

Family

BES1

Protein Properties

Length: 315aa MW: 34788.6 Da PI: 9.6762

Description

BES1 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Rsa1.0_05242.1_g00003.1	genome	RGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	DUF822	195	2.6e-60	16	147	3	142
DUF822 3 sgrkptwkErEnnkrRERrRRaiaakiyaGLRaqGnyklpkraDnneVlkALcreAGwvvedDGttyrkgskpleeaeaagssasa 88 +rkp+w+ErEnn+rRERrRRa+aakiy GLRaqGn++lp ++DnneVlkALc eAGwvve+DGttyrkg kpl ++agss++a Rsa1.0_05242.1_g00003.1 16 MTRKPSWRERENNRRRERRRRAVAAKIYNGLRAQGNFNLPRHCDNNEVLKALCSEAGWVVEEDGTTYRKGHKPL-PDDMAGSSSRA 100 68**********************************************************************.99***** PP DUF822 89 spesslqsslkssalaspvesysaspksssfpspssldsislasaasllpvlsv 142 +p ss++ s ++sp++sy+asp+sssfpsp d+ +++ +++p+ ++ Rsa1.0_05242.1_g00003.1 101 TPYSSYN----QSPFESPIHSYQASPSSSSFPSPRGGDTHNIS---TIFPFYRN 147 *99....889********************9999985...56666655 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF05687	1.3E-57	16	135	IPR008540	BES1/BZR1 plant transcription factor, N-terminal

Sequence ? help Back to Top
Protein Sequence Length: 315 aa Download sequence Send to blast
MTYEGATLTS AAAMAMTRKP SWRERENNRR RERRRRAVAA KIYNGLRAQG NFNLPRHCDN 60 NEVLKALCSE AGWVVEEDGT TYRKGHKPLP DDMAGSSSRA TPYSSYNQSP FESPIHSYQA 120 SPSSSSFPSP RGGDTHNIST IFPFYRNGGF PPLKTSNSAP VTPPVSSPTS RNTKPLPTWE 180 SLTRQSMANA ARQRTSSFNY PFYAVSAPAS PTNHRQFNAP ATIPECDESD STIDSSQWLS 240 SQKFSQQPFR GGFAVPPSPT FNLMKPLLPE LVSSNNLTAP EIGQNSQVKP WEGERIHDVA 300 MEDLELTLGN SKGRS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5zd4_A	9e-33	18	99	372	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_B	9e-33	18	99	372	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_C	9e-33	18	99	372	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_D	9e-33	18	99	372	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
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Functional Description ? help Back to Top
Source	Description
UniProt	Positive regulator of brassinosteroid (BR) signaling. Transcription factor that activates target gene expression by binding specifically to the DNA sequence 5'-CANNTG-3'(E box) through its N-terminal domain. Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BIM1, BIM2 or BIM3. The C-terminal domain is probably involved in transcriptional activation (PubMed:12007405, PubMed:15680330, PubMed:18467490, PubMed:19170933). Recruits the transcription elongation factor IWS1 to control BR-regulated gene expression (PubMed:20139304). Forms a trimeric complex with IWS1 and ASHH2/SDG8 to regulate BR-regulated gene expression (PubMed:24838002). Promotes quiescent center (QC) self-renewal by cell divisions in the primary root. Binds to the E-boxes of the BRAVO promoter to repress its expression (PubMed:24981610). {ECO:0000269\|PubMed:12007405, ECO:0000269\|PubMed:15680330, ECO:0000269\|PubMed:18467490, ECO:0000269\|PubMed:19170933, ECO:0000269\|PubMed:20139304, ECO:0000269\|PubMed:24838002, ECO:0000269\|PubMed:24981610}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Rsa1.0_05242.1_g00003.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK352751	0.0	AK352751.1 Thellungiella halophila mRNA, complete cds, clone: RTFL01-07-K05.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018438162.1	0.0	PREDICTED: protein BRASSINAZOLE-RESISTANT 2-like
Refseq	XP_018438164.1	0.0	PREDICTED: protein BRASSINAZOLE-RESISTANT 2-like
Swissprot	Q9LN63	1e-146	BZR2_ARATH; Protein BRASSINAZOLE-RESISTANT 2
TrEMBL	A0A078G5C8	1e-178	A0A078G5C8_BRANA; BnaA09g44210D protein
TrEMBL	A0A397YB44	1e-178	A0A397YB44_BRACM; Uncharacterized protein
TrEMBL	A0A3P5Y899	1e-178	A0A3P5Y899_BRACM; Uncharacterized protein
TrEMBL	M4EQK6	1e-178	M4EQK6_BRARP; Uncharacterized protein
STRING	Bra031077.1-P	1e-179	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2472	27	72

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G19350.6	1e-127	BES1 family protein

Publications ? help Back to Top
Salazar-Henao JE,Lehner R,Betegón-Putze I,Vilarrasa-Blasi J,Caño-Delgado AI BES1 regulates the localization of the brassinosteroid receptor BRL3 within the provascular tissue of the Arabidopsis primary root. J. Exp. Bot., 2016. 67(17): p. 4951-61 [PMID:27511026] Nolan T, et al. Identification of Brassinosteroid Target Genes by Chromatin Immunoprecipitation Followed by High-Throughput Sequencing (ChIP-seq) and RNA-Sequencing. Methods Mol. Biol., 2017. 1564: p. 63-79 [PMID:28124247] Ye H, et al. RD26 mediates crosstalk between drought and brassinosteroid signalling pathways. Nat Commun, 2017. 8: p. 14573 [PMID:28233777] Nolan TM, et al. Selective Autophagy of BES1 Mediated by DSK2 Balances Plant Growth and Survival. Dev. Cell, 2017. 41(1): p. 33-46.e7 [PMID:28399398] Yang M, et al. SINAT E3 Ligases Control the Light-Mediated Stability of the Brassinosteroid-Activated Transcription Factor BES1 in Arabidopsis. Dev. Cell, 2017. 41(1): p. 47-58.e4 [PMID:28399399] Chen J, et al. Arabidopsis WRKY46, WRKY54, and WRKY70 Transcription Factors Are Involved in Brassinosteroid-Regulated Plant Growth and Drought Responses. Plant Cell, 2017. 29(6): p. 1425-1439 [PMID:28576847] Yang M,Wang X Multiple Ways of BES1/BZR1 Degradation to Decode Distinct Developmental and Environmental Cues in Plants. Mol Plant, 2017. 10(7): p. 915-917 [PMID:28629641] Saito M,Kondo Y,Fukuda H BES1 and BZR1 Redundantly Promote Phloem and Xylem Differentiation. Plant Cell Physiol., 2018. 59(3): p. 590-600 [PMID:29385529] Liang T, et al. UVR8 Interacts with BES1 and BIM1 to Regulate Transcription and Photomorphogenesis in Arabidopsis. Dev. Cell, 2018. 44(4): p. 512-523.e5 [PMID:29398622]