PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00000992-RA_Salv
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family bHLH
Protein Properties Length: 501aa    MW: 55576.3 Da    PI: 5.6508
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00000992-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH36.77.5e-12355401455
                            HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
                    HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                            +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L   + YI +Lq
  SMil_00000992-RA_Salv 355 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDSIAYITDLQ 401
                            799***********************66......*****************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142153.4E-3849228IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.387351400IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.04E-13354405No hitNo description
SuperFamilySSF474592.09E-17354420IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.3E-9355401IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.109.5E-17355412IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.1E-14357406IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 501 aa     Download sequence    Send to blast
MGKKVWWNEE EKVVVESVLG SEATEYFDWA ASNNVLSEFS TSSGDLGVQE ALCKIVEGSD  60
LTYAIYWHVS KSKSGRSALI WGDGHYQESK ESVHDSCGSY NDLKRVEGDR RKWVLQKLHA  120
CFGGLEDDNV AAKLDQVSNV EMLYLTSMFF VFPFDKPSIP SQSFNSDRCI WVSNLDSCLE  180
RYHSRAYLAK LAQFETVAFV PTKSGVVEIG SRKSIPENKS IIKAAKSIVV AFNSTQVKAV  240
PKIFGQDLSM GGSRSGTINI SFSPKVEDDS GFSAESYDLQ AISSNHGYAN SSNGHCGDDG  300
DTKVFSHHVV AAGLDSQSII SGMELGKEDC FFLSDDQRPR KRGRKPANGR EEPLNHVEAE  360
RQRREKLNQR FYALRAVVPN ISKMDKASLL GDSIAYITDL QAKIRVLEAE KGIGNTNQQL  420
NPIPDFEFHE RLEDAVLRVS YTLETHPVSK VVKALREQQV MAQESSISID DSGEVVHTFS  480
IQTESGDAEQ LKDKLTAALL K
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A6e-29349411264Transcription factor MYC2
5gnj_B6e-29349411264Transcription factor MYC2
5gnj_E6e-29349411264Transcription factor MYC2
5gnj_F6e-29349411264Transcription factor MYC2
5gnj_G6e-29349411264Transcription factor MYC2
5gnj_I6e-29349411264Transcription factor MYC2
5gnj_M6e-29349411264Transcription factor MYC2
5gnj_N6e-29349411264Transcription factor MYC2
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00099PBMTransfer from AT4G16430Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKP2574700.0KP257470.1 Salvia miltiorrhiza clone 37 basic helix-loop-helix transcription factor mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011080018.10.0transcription factor bHLH3-like
RefseqXP_011080019.10.0transcription factor bHLH3-like
SwissprotA0A3Q7H2160.0MTB3_SOLLC; Transcription factor MTB3
TrEMBLA0A0H3YC310.0A0A0H3YC31_SALMI; Basic helix-loop-helix transcription factor
STRINGMigut.D00401.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA66692433
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16430.11e-141bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]