PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00008818-RA_Salv
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family C2H2
Protein Properties Length: 232aa    MW: 26280.2 Da    PI: 10.2849
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00008818-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H216.62.1e-055575323
                           ETTTTEEESSHHHHHHHHHHT CS
                zf-C2H2  3 CpdCgksFsrksnLkrHirtH 23
                           C++Cgk F r  nL+ H r H
  SMil_00008818-RA_Salv 55 CEICGKGFQRDQNLQLHKRGH 75
                           ******************988 PP
2zf-C2H212.80.00035129151123
                            EEETTTTEEESSHHHHHHHHHHT CS
                zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                            +kC +C+k++  +s+ k H +t+
  SMil_00008818-RA_Salv 129 WKCDKCSKRYAVHSDWKAHYKTC 151
                            58*******************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.607.8E-75075IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576673.22E-65175No hitNo description
PROSITE profilePS5015711.4485375IPR007087Zinc finger, C2H2
SMARTSM003550.0745375IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002805575IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.606.3E-4117150IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576673.22E-6124149No hitNo description
SMARTSM0035598129149IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 232 aa     Download sequence    Send to blast
MTTEEEAVST VNKAVQASNP PPLKKKRNLP GNPDPEAEVM ALSPKTLMAT KRFLCEICGK  60
GFQRDQNLQL HKRGHNLPWK LKQRTSKEIR KRVYVCPEKT CVHHHASRAL GDLTGIKKHF  120
CRKHGDKKWK CDKCSKRYAV HSDWKAHYKT CGTREYKCDC ATTFSRRDSF ITHRAFCDAL  180
AEETARFTAA SHMSSNQAAP NLNYHFIGSS LGLGQQHLLP PIFKSNSATT KT
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3h_C1e-33125192370Zinc finger protein JACKDAW
5b3h_F1e-33125192370Zinc finger protein JACKDAW
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440). Interacts with the SCR and MGP promoters (PubMed:21935722). Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Positively involved in gibberellic acid (GA) signaling (PubMed:24821766). {ECO:0000269|PubMed:17785527, ECO:0000269|PubMed:21935722, ECO:0000269|PubMed:24821766, ECO:0000269|PubMed:25829440}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by the transcription factor JKD, and down-regulated by SHR, SCR and itself. {ECO:0000269|PubMed:21935722}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009587634.11e-132PREDICTED: zinc finger protein MAGPIE
SwissprotQ9ZWA61e-125IDD3_ARATH; Zinc finger protein MAGPIE
TrEMBLA0A4D8XYB41e-142A0A4D8XYB4_SALSN; Uncharacterized protein
STRINGXP_009587634.11e-131(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA10324350
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G03840.11e-114C2H2 family protein
Publications ? help Back to Top
  1. Muñoz-Strale D,León G
    Identification of two highly specific pollen promoters using transcriptomic data.
    Plant Physiol. Biochem., 2014. 83: p. 292-9
    [PMID:25208507]
  2. Moreno-Risueno MA, et al.
    Transcriptional control of tissue formation throughout root development.
    Science, 2015. 350(6259): p. 426-30
    [PMID:26494755]