PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

SMil_00009935-RA_Salv

Organism

Salvia miltiorrhiza

Taxonomic ID

226208

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia

Family

NAC

Protein Properties

Length: 271aa MW: 31236.4 Da PI: 6.351

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
SMil_00009935-RA_Salv	genome	NDCTCM	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	160.5	6.6e-50	14	141	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.kkvkaeekewyfFskrdkkyatgkrknratksgyWkatg 87 +ppGfrFhPtd e++++yL +kv + ++++ + i++++++++ePwdLp k++k +e+ew+fF++++ ky++g+r+nrat+sgyWk+tg SMil_00009935-RA_Salv 14 MPPGFRFHPTDLEIITHYLLNKVLDVRFRA-QPIRDIHLNNFEPWDLPpKAAKMGENEWFFFFEKECKYPSGRRTNRATASGYWKSTG 100 79*************************9.88**********978888999**************************** PP NAM 88 kdkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128 kd+e++++++ +vg+kktLvfykgrapk++kt+Wv+ eyrl SMil_00009935-RA_Salv 101 KDREIHNATKMVVGMKKTLVFYKGRAPKAHKTNWVIREYRL 141 *************************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	6.28E-57	10	166	IPR003441	NAC domain
PROSITE profile	PS51005	53.463	14	166	IPR003441	NAC domain
Pfam	PF02365	5.2E-26	15	141	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 271 aa Download sequence Send to blast
MEEEEEESSA VAEMPPGFRF HPTDLEIITH YLLNKVLDVR FRAQPIRDIH LNNFEPWDLP 60 PKAAKMGENE WFFFFEKECK YPSGRRTNRA TASGYWKSTG KDREIHNATK MVVGMKKTLV 120 FYKGRAPKAH KTNWVIREYR LHGDFSAYNL SHHAKEKWVV CRVFHKKDVP VVDPPLPPLT 180 DHYSSEKASL SFATDEIIKP SALNSCEDGL SWWSPNLTDK PNSRILYTGG NEIERLMEMA 240 TADCEKEISD GSNKACEGLC DILDMDSLWT Y

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	2e-42	1	167	4	166	NO APICAL MERISTEM PROTEIN
1ut4_B	2e-42	1	167	4	166	NO APICAL MERISTEM PROTEIN
1ut7_A	2e-42	1	167	4	166	NO APICAL MERISTEM PROTEIN
1ut7_B	2e-42	1	167	4	166	NO APICAL MERISTEM PROTEIN
3swm_A	2e-42	1	167	7	169	NAC domain-containing protein 19
3swm_B	2e-42	1	167	7	169	NAC domain-containing protein 19
3swm_C	2e-42	1	167	7	169	NAC domain-containing protein 19
3swm_D	2e-42	1	167	7	169	NAC domain-containing protein 19
3swp_A	2e-42	1	167	7	169	NAC domain-containing protein 19
3swp_B	2e-42	1	167	7	169	NAC domain-containing protein 19
3swp_C	2e-42	1	167	7	169	NAC domain-containing protein 19
3swp_D	2e-42	1	167	7	169	NAC domain-containing protein 19
4dul_A	2e-42	1	167	4	166	NAC domain-containing protein 19
4dul_B	2e-42	1	167	4	166	NAC domain-containing protein 19
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that acts as positive regulator of leaf senescence. Activates NYC1, SGR1, SGR2 and PAO, which are genes involved in chlorophyll catabolic processes. Activates senescence-associated genes, such as RNS1, SAG12 and SAG13. {ECO:0000269\|PubMed:27021284}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed post-transcriptionally by miR164. {ECO:0000269\|PubMed:15294871, ECO:0000269\|PubMed:17098808, ECO:0000269\|PubMed:18305205, ECO:0000305\|PubMed:15723790}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011078584.1	2e-75	NAC domain-containing protein 92
Swissprot	Q9FLR3	3e-67	NAC79_ARATH; NAC domain-containing protein 79
Swissprot	Q9SQQ6	4e-67	NAC46_ARATH; NAC domain-containing protein 46
TrEMBL	A0A1U8BIE1	1e-70	A0A1U8BIE1_NELNU; NAC domain-containing protein 72-like
STRING	XP_010276452.1	2e-71	(Nelumbo nucifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA152	24	279

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G04060.1	1e-69	NAC domain containing protein 46

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Vidal EA,Álvarez JM,Gutiérrez RA Nitrate regulation of AFB3 and NAC4 gene expression in Arabidopsis roots depends on NRT1.1 nitrate transport function. Plant Signal Behav, 2014. 9(3): p. e28501 [PMID:24642706] Oda-Yamamizo C, et al. Corrigendum: The NAC transcription factor ANAC046 is a positive regulator of chlorophyll degradation and senescence in Arabidopsis leaves. Sci Rep, 2016. 6: p. 35125 [PMID:27759025] O'Shea C, et al. Structures and Short Linear Motif of Disordered Transcription Factor Regions Provide Clues to the Interactome of the Cellular Hub Protein Radical-induced Cell Death1. J. Biol. Chem., 2017. 292(2): p. 512-527 [PMID:27881680] Lee MH,Jeon HS,Kim HG,Park OK An Arabidopsis NAC transcription factor NAC4 promotes pathogen-induced cell death under negative regulation by microRNA164. New Phytol., 2017. 214(1): p. 343-360 [PMID:28032643]