PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00019538-RA_Salv
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family bHLH
Protein Properties Length: 552aa    MW: 61173.9 Da    PI: 7.8336
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00019538-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH39.78.9e-13435481455
                            HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
                    HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                            +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI +Lq
  SMil_00019538-RA_Salv 435 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYITELQ 481
                            799***********************66......*****************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142153.4E-5352241IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.85431480IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474592.09E-18434494IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000838.19E-14434485No hitNo description
Gene3DG3DSA:4.10.280.102.2E-17435493IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000103.0E-10435481IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003536.5E-17437486IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 552 aa     Download sequence    Send to blast
MRKESSMAGI GWNDEDRAMA SAVLGTKAFD YLMSNNVSAE CSLMAMTNDE NLQNKLSDLV  60
ERPNSANFSW NYAIFWQLSR SRAGDLVLGW GDGCCREPRE IEEDSDVTRF LRIRQEDECQ  120
QRMRKRVLQK LHISFGGSED ESYAFGLDKV TDAEMFFLAS MYFSYARGEG GPGRCFSSGE  180
HLWLSDAFKS PVDYCVRSFL ARSAGVQTIV LVPTDIGVVE LGSIRCVPES LELVKVVRSS  240
FSSLSGVLRS KKAVAVAVAA ENDRSNPKSG FGEVIPKIFG QDLCSGRVEL KEKVDVRKVG  300
YGAMDASANG NGNGNGNGQP FANGFHAMVW RQYGNVNVKP ANPVEVCKNP PRPTKHVNDM  360
VNGARDGQHR KPAQMQIDFA GATARPVSSR PRSAESEHSD IEAPCKEEGM VVVSEDNRPR  420
KRGRKPANGR EEPLNHVEAE RQRREKLNQR FYALRAVVPN ISKMDKASLL GDAIAYITEL  480
QNKLKELESS KESRLSREAS VSETQPNTET PACIPSIDIQ AGREEVTLKV SCQLDAHPYR  540
GSFERSRMLG RP
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A6e-29429491264Transcription factor MYC2
5gnj_B6e-29429491264Transcription factor MYC2
5gnj_E6e-29429491264Transcription factor MYC2
5gnj_F6e-29429491264Transcription factor MYC2
5gnj_G6e-29429491264Transcription factor MYC2
5gnj_I6e-29429491264Transcription factor MYC2
5gnj_M6e-29429491264Transcription factor MYC2
5gnj_N6e-29429491264Transcription factor MYC2
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKP2574860.0KP257486.1 Salvia miltiorrhiza clone 53 basic helix-loop-helix transcription factor mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011093025.10.0transcription factor bHLH13-like isoform X1
RefseqXP_011093026.10.0transcription factor bHLH13-like isoform X1
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A0H3Y7J20.0A0A0H3Y7J2_SALMI; Basic helix-loop-helix transcription factor
STRINGMigut.N01539.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA35852348
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.31e-149bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]