PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

SMil_00019567-RA_Salv

Organism

Salvia miltiorrhiza

Taxonomic ID

226208

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia

Family

HSF

Protein Properties

Length: 269aa MW: 29475.9 Da PI: 7.273

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
SMil_00019567-RA_Salv	genome	NDCTCM	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	118.5	3.9e-37	10	102	2	103
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkg 89 Fl+k+y++++d++ +++isw+e g++fvv+++ efak++Lp+yFkh+nf+SFvRQLn+YgF+k+ ++ weF++++Fk+g SMil_00019567-RA_Salv 10 FLTKTYNLVDDPASDDVISWNEAGTAFVVWKTAEFAKDLLPNYFKHNNFSSFVRQLNTYGFRKTVPDK---------WEFANENFKRG 88 9*************************************************************9999.........******* PP XXXXXXXXXXXXXX CS HSF_DNA-bind 90 kkellekikrkkse 103 +kell +i+r+k++ SMil_00019567-RA_Salv 89 QKELLVQIRRRKTA 102 *********975 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.8E-38	3	94	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	2.8E-60	6	99	IPR000232	Heat shock factor (HSF)-type, DNA-binding
SuperFamily	SSF46785	9.52E-34	7	99	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF00447	8.7E-33	10	99	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	4.4E-20	10	33	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	4.4E-20	48	60	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	4.4E-20	61	73	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009408	Biological Process	response to heat
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 269 aa Download sequence Send to blast
MAQRSVPAPF LTKTYNLVDD PASDDVISWN EAGTAFVVWK TAEFAKDLLP NYFKHNNFSS 60 FVRQLNTYGF RKTVPDKWEF ANENFKRGQK ELLVQIRRRK TATTTQNPAN GRAGAGAGDN 120 LASPATSGED LGSSSTSSPD SKNPSSLETQ ATAQLADLSG ENEKLRKDNQ MLSYELAQTK 180 KQCDELIAFL TQCVKVAPDE ISHIMNLGAK SAGYGNADCG DDEDNDENDK CMKLFGVVVK 240 KKRGCCSGGG ADLCGPHKKQ MKPWMESNK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ldu_A	1e-26	5	104	16	125	Heat shock factor protein 1
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Functional Description ? help Back to Top
Source	Description
UniProt	DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011099137.1	1e-139	heat shock factor protein HSF24
Swissprot	P22335	1e-101	HSF24_SOLPE; Heat shock factor protein HSF24
TrEMBL	A0A2G9GXX1	1e-139	A0A2G9GXX1_9LAMI; Uncharacterized protein
STRING	VIT_07s0031g00670.t01	1e-114	(Vitis vinifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA9991	21	27

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36990.1	2e-73	heat shock factor 4

Publications ? help Back to Top
Scharf KD, et al. Three tomato genes code for heat stress transcription factors with a region of remarkable homology to the DNA-binding domain of the yeast HSF. EMBO J., 1990. 9(13): p. 4495-501 [PMID:2148291]