PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00023118-RA_Salv
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family bHLH
Protein Properties Length: 84aa    MW: 9533.86 Da    PI: 8.5134
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00023118-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH309.1e-1015531454
                           HHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS
                    HLH 14 driNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54
                           d+iN+ + +L+ llP  +   +++++s ++iL+++++Y+k+L
  SMil_00023118-RA_Salv 15 DEINDLILKLQPLLPDsR---SNTRVSASMILKETCNYLKKL 53
                           78**************66...*******************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088810.493153IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003530.0068459IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.59E-51557No hitNo description
Gene3DG3DSA:4.10.280.101.9E-101568IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.0E-61553IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.44E-101569IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 84 aa     Download sequence    Send to blast
MSSSSRERSS RITEDEINDL ILKLQPLLPD SRSNTRVSAS MILKETCNYL KKLHKEVDDL  60
SERLSQLLAS GSFDADAIRA LLRR
Functional Description ? help Back to Top
Source Description
UniProtAtypical and probable non DNA-binding bHLH transcription factor required for MONOPTEROS-dependent root initiation in embryo. Promotes the correct definition of the hypophysis cell division plane. Transcriptionally controlled by MONOPTEROS. Moves from its site of synthesis in pro-embryos cells into the hypophysis. Regulates brassinosteroid (BR) signaling by sequestering negative BR signaling components. May function as positive regulator of gibberellin signaling. May play a role in the regulation of light signaling and possibly auxin signaling. {ECO:0000269|PubMed:16527868, ECO:0000269|PubMed:20023194, ECO:0000269|PubMed:20220754, ECO:0000269|PubMed:22339648}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Not induced by exogenous gibberellin. {ECO:0000269|PubMed:16527868}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKP2575041e-140KP257504.1 Salvia miltiorrhiza clone 71 basic helix-loop-helix transcription factor mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011087225.12e-34transcription factor ILI5-like
SwissprotQ9CA643e-22PRE3_ARATH; Transcription factor PRE3
TrEMBLA0A0H3YBT83e-51A0A0H3YBT8_SALMI; Basic helix-loop-helix transcription factor
STRINGMigut.D01841.1.p4e-32(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA35324161
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G74500.19e-25activation-tagged BRI1(brassinosteroid-insensitive 1)-suppressor 1
Publications ? help Back to Top
  1. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  2. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]
  3. Lu KJ,De Rybel B,van Mourik H,Weijers D
    Regulation of intercellular TARGET OF MONOPTEROS 7 protein transport in the Arabidopsis root.
    Development, 2018.
    [PMID:29358212]
  4. Baesso B, et al.
    Transcription factors PRE3 and WOX11 are involved in the formation of new lateral roots from secondary growth taproot in A. thaliana.
    Plant Biol (Stuttg), 2018. 20(3): p. 426-432
    [PMID:29450949]