PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

SMil_00023563-RA_Salv

Organism

Salvia miltiorrhiza

Taxonomic ID

226208

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia

Family

bHLH

Protein Properties

Length: 219aa MW: 24421 Da PI: 8.9185

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
SMil_00023563-RA_Salv	genome	NDCTCM	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26.4	1.2e-08	129	169	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR+ri +++ L++l+P +K++ a++L +A++Y+k L SMil_00023563-RA_Salv 129 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAIHYVKFL 169 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.218	120	169	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.31E-14	125	180	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	5.5E-13	125	178	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	6.3E-14	126	175	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	5.9E-6	130	169	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	9.84E-7	143	174	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010500	Biological Process	transmitting tissue development
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0048462	Biological Process	carpel formation
GO:2000012	Biological Process	regulation of auxin polar transport
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 219 aa Download sequence Send to blast
MDIEFIKNGG EDQMEMMLMQ MEKLPDLSGA YADVNDLPII DFAPHNQLTD FQNLHASSPP 60 PPLHPASTIS FSGQFQPGEA AQKRSSMAAM REMIFRIAAM QPIHIDPESV RPPKRRNVRI 120 STDPQSVAAR HRRERISERI RILQRLVPGG TKMDTASMLD EAIHYVKFLK NQVQSLERVA 180 ANRPPPPGMG FPVPMSSGSY FPVAGKGYHQ AANVQHLAE

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	110	115	RPPKRR

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KP257546	0.0	KP257546.1 Salvia miltiorrhiza clone 114 basic helix-loop-helix transcription factor mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011074418.1	2e-99	transcription factor HEC2-like
Swissprot	Q9FHA7	5e-47	HEC1_ARATH; Transcription factor HEC1
TrEMBL	A0A0H3Y7N5	1e-159	A0A0H3Y7N5_SALMI; Basic helix-loop-helix transcription factor
STRING	Migut.N02717.1.p	4e-82	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA752	23	101

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G67060.1	9e-42	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Vercruyssen L, et al. ANGUSTIFOLIA3 binds to SWI/SNF chromatin remodeling complexes to regulate transcription during Arabidopsis leaf development. Plant Cell, 2014. 26(1): p. 210-29 [PMID:24443518] Sparks EE,Benfey PN HEC of a job regulating stem cells. Dev. Cell, 2014. 28(4): p. 349-50 [PMID:24576420] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231] Lozano-Sotomayor P, et al. Altered expression of the bZIP transcription factor DRINK ME affects growth and reproductive development in Arabidopsis thaliana. Plant J., 2016. 88(3): p. 437-451 [PMID:27402171] Boex-Fontvieille E, et al. An Ethylene-Protected Achilles' Heel of Etiolated Seedlings for Arthropod Deterrence. Front Plant Sci, 2016. 7: p. 1246 [PMID:27625656] Gaillochet C, et al. Control of plant cell fate transitions by transcriptional and hormonal signals. Elife, 2018. [PMID:29058667]