PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00026667-RA_Salv
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family HD-ZIP
Protein Properties Length: 240aa    MW: 27385.2 Da    PI: 4.3407
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00026667-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox60.13.4e-1952105356
                            --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
               Homeobox   3 kRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 
                            k+++++ +q+++Le+ Fe ++++  e++ +LA++lgL+ rqV vWFqNrRa++k
  SMil_00026667-RA_Salv  52 KKRRLSVDQVKALEKNFEVENKLEPERKVKLAQELGLQPRQVAVWFQNRRARWK 105
                            566899***********************************************9 PP
2HD-ZIP_I/II1309.2e-4251142192
            HD-ZIP_I/II   1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLr 88 
                            ekkrrls +qvk+LE++Fe e+kLeperKv+la+eLglqprqvavWFqnrRAR+ktkqlE+dy  Lk++yd lk + erL++++e+L 
  SMil_00026667-RA_Salv  51 EKKRRLSVDQVKALEKNFEVENKLEPERKVKLAQELGLQPRQVAVWFQNRRARWKTKQLERDYGGLKASYDGLKLNFERLQRDNESLL 138
                            69*************************************************************************************9 PP

            HD-ZIP_I/II  89 eelk 92 
                            +el+
  SMil_00026667-RA_Salv 139 KELN 142
                            9885 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466893.68E-1945109IPR009057Homeodomain-like
PROSITE profilePS5007117.44347107IPR001356Homeobox domain
SMARTSM003896.3E-1850111IPR001356Homeobox domain
PfamPF000462.2E-1652105IPR001356Homeobox domain
CDDcd000865.71E-1652108No hitNo description
Gene3DG3DSA:1.10.10.603.7E-2054113IPR009057Homeodomain-like
PRINTSPR000315.7E-67887IPR000047Helix-turn-helix motif
PROSITE patternPS00027082105IPR017970Homeobox, conserved site
PRINTSPR000315.7E-687103IPR000047Helix-turn-helix motif
PfamPF021831.4E-14107142IPR003106Leucine zipper, homeobox-associated
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009414Biological Processresponse to water deprivation
GO:0009788Biological Processnegative regulation of abscisic acid-activated signaling pathway
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 240 aa     Download sequence    Send to blast
MKRLSNSDSL GGLMSICPNA TEEESNNPMY AREFQTMLEG LEEEESGHVS EKKRRLSVDQ  60
VKALEKNFEV ENKLEPERKV KLAQELGLQP RQVAVWFQNR RARWKTKQLE RDYGGLKASY  120
DGLKLNFERL QRDNESLLKE LNGDDEEKTR LESEIGGAEA EMENPEGGKK EEASWPKFGD  180
GSSDSDSSAI LNEENIGFQL GAPQLVKIEE HNFFGEESCS TLFSDDQPPS LPWYCNDQWD
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
199107RRARWKTKQ
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that may act as growth regulators in response to water deficit. Interacts with the core sequence 5'-CAATTATTA-3' of promoters in response to ABA and in an ABI1-dependent manner. Involved in the negative regulation of the ABA signaling pathway. {ECO:0000269|PubMed:10527431, ECO:0000269|PubMed:12065416}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00271DAPTransfer from AT2G22430Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By water deficit, by abscisic acid (ABA) and by salt stress. Self expression regulation. {ECO:0000269|PubMed:10527431, ECO:0000269|PubMed:12065416, ECO:0000269|PubMed:16055682}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011097532.11e-104homeobox-leucine zipper protein ATHB-6
SwissprotP466683e-70ATHB6_ARATH; Homeobox-leucine zipper protein ATHB-6
TrEMBLA0A4D9AYZ91e-104A0A4D9AYZ9_SALSN; Homeobox-leucine zipper protein
STRINGMigut.L00161.1.p1e-101(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA27182453
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G22430.11e-71homeobox protein 6
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Song L, et al.
    A transcription factor hierarchy defines an environmental stress response network.
    Science, 2017.
    [PMID:27811239]