PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

SMil_00029807-RA_Salv

Organism

Salvia miltiorrhiza

Taxonomic ID

226208

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia

Family

C2H2

Protein Properties

Length: 499aa MW: 56181.6 Da PI: 6.2027

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
SMil_00029807-RA_Salv	genome	NDCTCM	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	21.1	8.3e-07	249	270	2	23
EETTTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCpdCgksFsrksnLkrHirtH 23 C++Cgk F+r nL+ H+r H SMil_00029807-RA_Salv 249 FCTICGKGFKRDANLRMHMRGH 270 6*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	2.11E-5	246	273	No hit	No description
SMART	SM00355	0.0026	248	270	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	12.03	248	275	IPR007087	Zinc finger, C2H2
Pfam	PF12874	0.001	249	270	No hit	No description
Gene3D	G3DSA:3.30.160.60	7.4E-6	249	299	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	250	270	IPR007087	Zinc finger, C2H2
SMART	SM00355	58	297	330	IPR015880	Zinc finger, C2H2-like
SMART	SM00355	22	335	357	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010044	Biological Process	response to aluminum ion
GO:0010447	Biological Process	response to acidic pH
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 499 aa Download sequence Send to blast
MDPDERLCAT TWAKSSSGHE SLNTHSNNRS LTDFDRQQQK WEESSFHGYG VRTSDQQFSG 60 FKRPFASNVD SQRQMNDLHG KQIPEAHELD NMQNWDPRAM LNNLSFLENK IHQLQDLVHL 120 VVGRRGQAMS QADEILVQQQ QLITADLTSI IVQLISTAGS LLPSVKNSEN LTSQLGQFSG 180 TASQSAGVLD NVVHNNANKM EDQHDPTGVF EDHDMKSDDD AEEGENLPPG SYEILQLEKE 240 EILAPHTHFC TICGKGFKRD ANLRMHMRGH GDEYKTPAAL AKPHKESSTE PILIKRYSCP 300 YVGCKRNKDH KKFQPLKTIL CVKNHYKRTH CDKNYTCSRC NTKKFSVIAD LKTHEKHCGR 360 DKWLCSCGTT FSRKDKLFGH IALFQGHTPA IPLEGAGPSD QGQSSVEAAN KVEQLDFNYK 420 LDDPRRSVLQ SIMEVEGPGE EDPASYFSPL GFDTSNMAGF QEFPRPLFED TESPFSFLLS 480 ASCDYPPKNE RYAAPNDLE

Sequence ? help Back to Top

Protein Sequence Length: 499 aa Download sequence Send to blast

MDPDERLCAT TWAKSSSGHE SLNTHSNNRS LTDFDRQQQK WEESSFHGYG VRTSDQQFSG  60
FKRPFASNVD SQRQMNDLHG KQIPEAHELD NMQNWDPRAM LNNLSFLENK IHQLQDLVHL  120
VVGRRGQAMS QADEILVQQQ QLITADLTSI IVQLISTAGS LLPSVKNSEN LTSQLGQFSG  180
TASQSAGVLD NVVHNNANKM EDQHDPTGVF EDHDMKSDDD AEEGENLPPG SYEILQLEKE  240
EILAPHTHFC TICGKGFKRD ANLRMHMRGH GDEYKTPAAL AKPHKESSTE PILIKRYSCP  300
YVGCKRNKDH KKFQPLKTIL CVKNHYKRTH CDKNYTCSRC NTKKFSVIAD LKTHEKHCGR  360
DKWLCSCGTT FSRKDKLFGH IALFQGHTPA IPLEGAGPSD QGQSSVEAAN KVEQLDFNYK  420
LDDPRRSVLQ SIMEVEGPGE EDPASYFSPL GFDTSNMAGF QEFPRPLFED TESPFSFLLS  480
ASCDYPPKNE RYAAPNDLE

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269\|PubMed:17535918, ECO:0000269\|PubMed:18826429, ECO:0000269\|PubMed:19321711, ECO:0000269\|PubMed:23935008}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00196	ampDAP	Transfer from AT1G34370	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269\|PubMed:17535918}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011097108.1	0.0	LOW QUALITY PROTEIN: protein SENSITIVE TO PROTON RHIZOTOXICITY 1
Swissprot	Q9C8N5	0.0	STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBL	A0A4D9BXI7	0.0	A0A4D9BXI7_SALSN; Uncharacterized protein
STRING	cassava4.1_005470m	0.0	(Manihot esculenta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA4754	24	41

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G34370.2	0.0	C2H2 family protein

Publications ? help Back to Top
Kobayashi Y, et al. Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions. Plant Physiol., 2013. 163(1): p. 180-92 [PMID:23839867] Yokosho K,Yamaji N,Ma JF Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench). Plant Cell Physiol., 2014. 55(12): p. 2077-91 [PMID:25273892] Geng X, et al. LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis. Plant J., 2017. 90(3): p. 491-504 [PMID:28181322] Balzergue C, et al. Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation. Nat Commun, 2017. 8: p. 15300 [PMID:28504266] Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation. Front Plant Sci, 2017. 8: p. 822 [PMID:28567051] Jiang F, et al. Identification and characterization of suppressor mutants of stop1. BMC Plant Biol., 2017. 17(1): p. 128 [PMID:28738784] Daspute AA, et al. Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms. Front Plant Sci, 2017. 8: p. 1358 [PMID:28848571] Sharma A,Wai CM,Ming R,Yu Q Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis. Genome Biol Evol, 2017. 9(9): p. 2170-2190 [PMID:28922793] Zhang Y, et al. The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis. Front Plant Sci, 2018. 9: p. 118 [PMID:29491872]