PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Seita.2G430400.1.p

Common Name

LOC101774260, SETIT_031079mg

Organism

Setaria italica

Taxonomic ID

4555

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria

Family

ERF

Protein Properties

Length: 217aa MW: 23791.7 Da PI: 6.5126

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Seita.2G430400.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	59.6	7.5e-19	74	122	3	55
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+G+r+++ +g+W+AeIrdp + +r++lg+f tae Aa+a+++a+++++g Seita.2G430400.1.p 74 YRGIRRRP-WGKWAAEIRDPAK---GARVWLGTFATAEAAARAYDRAARRIRG 122 9*****.******843...4***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF54171	4.9E-22	73	131	IPR016177	DNA-binding domain
PROSITE profile	PS51032	24.632	73	130	IPR001471	AP2/ERF domain
SMART	SM00380	1.1E-37	73	136	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.0E-31	73	131	IPR001471	AP2/ERF domain
Pfam	PF00847	1.4E-12	74	122	IPR001471	AP2/ERF domain
CDD	cd00018	2.34E-15	74	131	No hit	No description
PRINTS	PR00367	2.5E-11	74	85	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.5E-11	96	112	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 217 aa Download sequence Send to blast
MCGGAIISEF IPQRDARGRA SGGKRGLCAE DLWPQAAAGF DDVPAAVDGY EFTGAASFPH 60 DQEPARKRER KTMYRGIRRR PWGKWAAEIR DPAKGARVWL GTFATAEAAA RAYDRAARRI 120 RGSKAKVNFP NEDPPPDDDD HLRQGMLPVS SCITDYDAAV MVGFFQQHHQ QQHPYVPDAV 180 PVMAAPPPED VAYVQHQDAG MDVWTFDGIN TATVPM*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2gcc_A	1e-22	74	130	6	63	ATERF1
3gcc_A	1e-22	74	130	6	63	ATERF1
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	64	72	ARKRERKTM
2	66	80	KRERKTMYRGIRRRP

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269\|PubMed:9159183}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Seita.2G430400.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By 1-aminocyclopropane-1-carboxylic acid (ACC, ethylene precursor), methyl jasmonate (MeJA), and Botrytis cinerea. Also induced by cadmium. {ECO:0000269\|PubMed:18836139, ECO:0000269\|PubMed:9159183}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	EU976870	1e-106	EU976870.1 Zea mays clone 992413 mRNA sequence.
GenBank	KJ728348	1e-106	KJ728348.1 Zea mays clone pUT6630 AP2-EREBP transcription factor (EREB200) mRNA, partial cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004958676.1	1e-158	ethylene-responsive transcription factor ERF098
Swissprot	P42736	7e-37	RAP23_ARATH; Ethylene-responsive transcription factor RAP2-3
TrEMBL	K3ZWU7	1e-157	K3ZWU7_SETIT; Uncharacterized protein
STRING	Si031079m	1e-158	(Setaria italica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP11585	28	36

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G16770.1	9e-29	ethylene-responsive element binding protein

Link Out ? help Back to Top
Phytozome	Seita.2G430400.1.p
Entrez Gene	101774260

Publications ? help Back to Top
Bueso E, et al. The lithium tolerance of the Arabidopsis cat2 mutant reveals a cross-talk between oxidative stress and ethylene. Plant J., 2007. 52(6): p. 1052-65 [PMID:17931347] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Chen YC, et al. Root defense analysis against Fusarium oxysporum reveals new regulators to confer resistance. Sci Rep, 2014. 4: p. 5584 [PMID:24998294] Deslauriers SD,Alvarez AA,Lacey RF,Binder BM,Larsen PB Dominant gain-of-function mutations in transmembrane domain III of ERS1 and ETR1 suggest a novel role for this domain in regulating the magnitude of ethylene response in Arabidopsis. New Phytol., 2015. 208(2): p. 442-55 [PMID:25988998] Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana. Plant Sci., 2015. 236: p. 37-43 [PMID:26025519] Gasch P, et al. Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis. Plant Cell, 2016. 28(1): p. 160-80 [PMID:26668304] Liu W, et al. Ethylene response factor AtERF72 negatively regulates Arabidopsis thaliana response to iron deficiency. Biochem. Biophys. Res. Commun., 2017. 491(3): p. 862-868 [PMID:28390898] Yao Y,Chen X,Wu AM ERF-VII members exhibit synergistic and separate roles in Arabidopsis. Plant Signal Behav, 2017. 12(6): p. e1329073 [PMID:28537474]