PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Seita.6G069500.1.p

Common Name

LOC101769522, SETIT_014339mg

Organism

Setaria italica

Taxonomic ID

4555

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria

Family

bHLH

Protein Properties

Length: 250aa MW: 26983.6 Da PI: 5.4417

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Seita.6G069500.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	31	4.5e-10	82	130	3	54
HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 +++ rE++RRd++N++f eL + l + + K +Ka+iL A++ + +L Seita.6G069500.1.p 82 TSKASREKQRRDKLNDRFLELGSTLEPG---KPIKADKAAILSDATRMVIQL 130 67889********************9...8999*********988777 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	2.75E-13	76	149	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	12.671	79	130	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.49E-8	80	135	No hit	No description
Gene3D	G3DSA:4.10.280.10	1.2E-12	82	153	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	2.2E-7	83	130	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.5E-8	85	136	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 250 aa Download sequence Send to blast
MSLPPAPAEG GGGGGSAGDD WFLDCGILDD LPAAACGAFP WDASPSSSNP SVEVGSYVNT 60 NDVFKEPGSN KRLRSGSSGR PTSKASREKQ RRDKLNDRFL ELGSTLEPGK PIKADKAAIL 120 SDATRMVIQL RSEAQQLKDT NGSLEEKIKE LKAEKDELRD EKQKLKLEKE SLEHQMKLMT 180 SAPAYMPHPT LMPAPFPQAP LAPFHPQGQA AGQKLMMPFV SYPGYPMWQF MPPSEVDTSK 240 DSEACPPVA*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Seita.6G069500.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004972892.1	0.0	transcription factor ILR3
Swissprot	Q9FH37	2e-72	ILR3_ARATH; Transcription factor ILR3
TrEMBL	K3YJC0	0.0	K3YJC0_SETIT; Uncharacterized protein
STRING	Si014339m	0.0	(Setaria italica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP2023	38	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	7e-50	bHLH family protein

Link Out ? help Back to Top
Phytozome	Seita.6G069500.1.p
Entrez Gene	101769522

Publications ? help Back to Top
Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]