PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sme2.5_00187.1_g00004.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum
Family MYB_related
Protein Properties Length: 476aa    MW: 53998.4 Da    PI: 5.6997
Description MYB_related family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sme2.5_00187.1_g00004.1genomeEGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding23.31.5e-073566132
                             TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHT CS
          Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmg 32
                             rg+WT eEd  l++ ++++G g+W++ ar  g
  Sme2.5_00187.1_g00004.1 35 RGSWTVEEDCTLINHIALHGEGRWNSLARSAG 66
                             89**************************9887 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS500906.9113068IPR017877Myb-like domain
SuperFamilySSF466896.06E-73166IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.608.6E-93266IPR009057Homeodomain-like
PfamPF002491.5E-53566IPR001005SANT/Myb domain
CDDcd001677.53E-53763No hitNo description
SuperFamilySSF534744.07E-9266268IPR029058Alpha/Beta hydrolase fold
PfamPF004506.5E-8566374IPR001563Peptidase S10, serine carboxypeptidase
Gene3DG3DSA:3.40.50.18205.6E-11367471IPR029058Alpha/Beta hydrolase fold
PRINTSPR007246.2E-2995107IPR001563Peptidase S10, serine carboxypeptidase
PRINTSPR007246.2E-29108118IPR001563Peptidase S10, serine carboxypeptidase
PRINTSPR007246.2E-29144169IPR001563Peptidase S10, serine carboxypeptidase
PROSITE patternPS001310158165IPR018202Serine carboxypeptidase, serine active site
SuperFamilySSF534744.07E-92303471IPR029058Alpha/Beta hydrolase fold
PfamPF004506.8E-19394468IPR001563Peptidase S10, serine carboxypeptidase
PROSITE patternPS005600439456IPR033124Serine carboxypeptidases, histidine active site
PRINTSPR007246.2E-29439452IPR001563Peptidase S10, serine carboxypeptidase
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006508Biological Processproteolysis
GO:0003677Molecular FunctionDNA binding
GO:0004185Molecular Functionserine-type carboxypeptidase activity
Sequence ? help Back to Top
Protein Sequence    Length: 476 aa     Download sequence    Send to blast
MEHREYVGFD LRREASIESN NSKDDENNNS LDLKRGSWTV EEDCTLINHI ALHGEGRWNS  60
LARSAGPGCS SIGYGAAVEL GPLLVQNNGA GLDFNEHSWN KEANLLFLES PVGVGFSYTN  120
TSSDLTNLDD DFAAEDAYNF LVNWLERFPE FKNREFFISG ESYAGHYVPQ LAELVYNRNK  180
DSKKYPYINL KGFIVGNPET NDYYDYKGIL EYAWSHAILY DSEYQKAKQA CDFKLSNWSY  240
ACNDAMQVLW DKYNEIDIYN IYGPKCLVNT PSSSASDIVS THDASHIKAP NHGFRRMNRI  300
PGGYDPCYTS FTAEYFNRLD VQIALHASTE GTQARNKWKS CSDPVFNTYD YNVFSVLPVY  360
ERLIKGGLKI WIFSLYKLNI HVAHSFLCFI QKVGDADGRV PVIGTRDCVE ALNLTLKSPW  420
HSWFLNKQVA GRIVEYEGLT FVTVRGAGHL VPLYKPSESL ALIHSFLTGE ELPSHR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1bcr_A3e-646527061262SERINE CARBOXYPEPTIDASE II
1bcs_A3e-646527061262SERINE CARBOXYPEPTIDASE II
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtActs as positive regulator of grain size by controlling grain width, filling and weight. High expression of GS5 in the grain is correlated with large grain size. {ECO:0000269|PubMed:22019783, ECO:0000269|PubMed:25711711}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by light. Circadian regulation with a peak of expression at dusk (PubMed:25711711). Down-regulated by abscisic acid (ABA) and brassinosteroid (BR) (PubMed:25711711). {ECO:0000269|PubMed:25711711}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0139990.0BT013999.1 Lycopersicon esculentum clone 133046F, mRNA sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006349848.10.0PREDICTED: serine carboxypeptidase-like 33
SwissprotQ5W7271e-179SCP26_ORYSJ; Serine carboxypeptidase-like 26
TrEMBLA0A0V0IAX90.0A0A0V0IAX9_SOLCH; Carboxypeptidase
STRINGPGSC0003DMT4000117540.0(Solanum tuberosum)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G48000.14e-10myb domain protein 112
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Cheng CH, et al.
    A fine physical map of the rice chromosome 5.
    Mol. Genet. Genomics, 2005. 274(4): p. 337-45
    [PMID:16261349]
  3. Tripathi LP,Sowdhamini R
    Cross genome comparisons of serine proteases in Arabidopsis and rice.
    BMC Genomics, 2006. 7: p. 200
    [PMID:16895613]
  4. Li Y, et al.
    Natural variation in GS5 plays an important role in regulating grain size and yield in rice.
    Nat. Genet., 2011. 43(12): p. 1266-9
    [PMID:22019783]
  5. Xu C, et al.
    Differential expression of GS5 regulates grain size in rice.
    J. Exp. Bot., 2015. 66(9): p. 2611-23
    [PMID:25711711]