PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sme2.5_00789.1_g00008.1
Organism
Solanum melongena
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum
Family C2H2
Protein Properties Length: 398aa    MW: 43660.9 Da    PI: 9.2707
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sme2.5_00789.1_g00008.1genomeEGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H216.62.3e-056183123
                             EEETTTTEEESSHHHHHHHHHHT CS
                  zf-C2H2  1 ykCpdCgksFsrksnLkrHirtH 23
                             + C++C+k F r  nL+ H r H
  Sme2.5_00789.1_g00008.1 61 FICEICNKGFQRDQNLQLHRRGH 83
                             89*******************88 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576677.35E-55984No hitNo description
Gene3DG3DSA:3.30.160.601.0E-56083IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.8456183IPR007087Zinc finger, C2H2
PfamPF121714.5E-56183IPR022755Zinc finger, double-stranded RNA binding
PROSITE patternPS0002806383IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 398 aa     Download sequence    Send to blast
MMSGDLFSIH PQQQQQVLLE TNPNPKANSS SKKRRNLPGT PDPDAEVIAI SPKTLMATNR  60
FICEICNKGF QRDQNLQLHR RGHNLPWKLK QRNKQEIVKK KVYICPEKTC VHHDPSRALG  120
DLTGKDSFIT HRAFCDALAE ESARITSVGT TNNLNFNQQQ QQPVGISQIG TSFGQDFTGM  180
TTGNPLHQHQ QKPRLSSLWL NQANNNMSAP SSNLFGLQDH HMAQIPSPNM FGGSSVSNQI  240
LATSTPAPPN PSTPMSATAL LQKAAQMGST KSTPNYFSNT LGVMHSSSSP SSNNTTQIFN  300
NQVFAKQTED YDQRNNILIN GCPNMNSSVN SKAINLDQAL LQTGGMHNQT VQFNLDNSLT  360
RDFLGMGNEG GQPFLPQELA KFASMNSAMG LSHYSSGH
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that, together with BIB, regulates tissue boundaries and asymmetric cell division by a rapid up-regulation of 'SCARECROW' (SCR), thus controlling the nuclear localization of 'SHORT-ROOT' (SHR) and restricting its action (PubMed:17785527, PubMed:25829440). Binds DNA via its zinc fingers (PubMed:28211915, PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Confines CYCD6 expression to the cortex-endodermis initial/daughter (CEI/CEID) tissues (PubMed:25829440). Required for radial patterning and stem cell maintenance (PubMed:17785527). Counteracted by 'MAGPIE' (MGP) (PubMed:17785527). Binds to the SCR and MGP promoter sequences (PubMed:21935722). Controls position-dependent signals that regulate epidermal-cell-type patterning (PubMed:20356954). {ECO:0000269|PubMed:17785527, ECO:0000269|PubMed:20356954, ECO:0000269|PubMed:21935722, ECO:0000269|PubMed:24821766, ECO:0000269|PubMed:25829440, ECO:0000269|PubMed:28211915}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Not regulated by SCR and SHR. {ECO:0000269|PubMed:21935722}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankEF5768131e-176EF576813.3 Solanum lycopersicum chromosome 9 clone C09HBa0072G22, complete sequence.
GenBankHG9754481e-176HG975448.1 Solanum pennellii chromosome ch09, complete genome.
GenBankHG9755211e-176HG975521.1 Solanum lycopersicum chromosome ch09, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006361805.20.0PREDICTED: zinc finger protein JACKDAW-like isoform X1
SwissprotQ700D22e-79IDD10_ARATH; Zinc finger protein JACKDAW
TrEMBLM0ZNC90.0M0ZNC9_SOLTU; Uncharacterized protein
STRINGPGSC0003DMT4000043900.0(Solanum tuberosum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA10324350
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03150.12e-64C2H2-like zinc finger protein
Publications ? help Back to Top
  1. Moreno-Risueno MA, et al.
    Transcriptional control of tissue formation throughout root development.
    Science, 2015. 350(6259): p. 426-30
    [PMID:26494755]
  2. Hirano Y, et al.
    Structure of the SHR-SCR heterodimer bound to the BIRD/IDD transcriptional factor JKD.
    Nat Plants, 2017. 3: p. 17010
    [PMID:28211915]
  3. Kobayashi A,Miura S,Kozaki A
    INDETERMINATE DOMAIN PROTEIN binding sequences in the 5'-untranslated region and promoter of the SCARECROW gene play crucial and distinct roles in regulating SCARECROW expression in roots and leaves.
    Plant Mol. Biol., 2017. 94(1-2): p. 1-13
    [PMID:28324206]
  4. Long Y, et al.
    In vivo FRET-FLIM reveals cell-type-specific protein interactions in Arabidopsis roots.
    Nature, 2017. 548(7665): p. 97-102
    [PMID:28746306]
  5. Bustillo-Avendaño E, et al.
    Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis.
    Plant Physiol., 2018. 176(2): p. 1709-1727
    [PMID:29233938]