PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sme2.5_04841.1_g00003.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum
Family MYB_related
Protein Properties Length: 456aa    MW: 50943.9 Da    PI: 9.6652
Description MYB_related family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sme2.5_04841.1_g00003.1genomeEGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding24.85e-08130172346
                              SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
          Myb_DNA-binding   3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                              +WT+eE ++l d++k++  + +  Ia +++ +Rt +++k+r+++
  Sme2.5_04841.1_g00003.1 130 SWTKEETDQLFDLCKRFDLR-FIIIADRFPSNRTVEELKDRYYS 172
                              7*******************.*********************96 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF162822.5E-31103177IPR032563DAMP1, SANT/Myb-like domain
SMARTSM007173.7E-8127176IPR001005SANT/Myb domain
SuperFamilySSF466894.52E-7127176IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.602.0E-6129174IPR009057Homeodomain-like
CDDcd116584.24E-19131173No hitNo description
PfamPF054995.7E-6323386IPR008468DNA methyltransferase 1-associated 1
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0000812Cellular ComponentSwr1 complex
GO:0035267Cellular ComponentNuA4 histone acetyltransferase complex
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 456 aa     Download sequence    Send to blast
MDAKDILGLP KNGPLMSQEK KSRPQKESQR KPDGISREVY ALTGGIAPLM PSIDINQLKR  60
RALSESEKIT WQWLPFTSSA RKDNLQLYHW VRVVNGVPPT GDYSFAKYNK SVDVIEYTDE  120
EYEKFLSNPS WTKEETDQLF DLCKRFDLRF IIIADRFPSN RTVEELKDRY YSVSRAITIA  180
RAPSPADVTG HPLVKEPYNI SQEIERKRAL SMVLSQTKLQ ERRDAEVLAE AKRISESRKA  240
AKVIACFEAA EETELPDVSD AAPEGAEKAA GIDVISTSTN AQLPSGIAAP PVSETASTLA  300
SLRMLRVYLR TYGLEQMVQA ASSSAGLRTI KRVEQTLQDL GVNLKPKVPT KLVCAEHLEL  360
RKEILTLLNL QKQVQYKEAE GSSYREGSYS ETPGTPPKRA QRAMDQDRTF IPDSASFGGE  420
RAIKSVQKRK GPGRLSEVPS SPAQSKRPRK LKTSDG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3hm5_A1e-21102187493DNA methyltransferase 1-associated protein 1
4iej_A1e-21102187493DNA methyltransferase 1-associated protein 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtComponent of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. {ECO:0000305|Ref.5}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0135620.0BT013562.1 Lycopersicon esculentum clone 132299F, mRNA sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006349165.10.0PREDICTED: SWR1-complex protein 4
SwissprotQ8VZL60.0SWC4_ARATH; SWR1-complex protein 4
TrEMBLM1AI920.0M1AI92_SOLTU; Uncharacterized protein
STRINGPGSC0003DMT4000233830.0(Solanum tuberosum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA76261515
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G47210.10.0MYB_related family protein
Publications ? help Back to Top
  1. Gómez-Zambrano Á, et al.
    Arabidopsis SWC4 Binds DNA and Recruits the SWR1 Complex to Modulate Histone H2A.Z Deposition at Key Regulatory Genes.
    Mol Plant, 2018. 11(6): p. 815-832
    [PMID:29604400]