PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sobic.001G387600.1.p
Common NameSb01g036740, SORBIDRAFT_01g036740
Organism
Sorghum bicolor
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum
Family EIL
Protein Properties Length: 644aa    MW: 71826.5 Da    PI: 4.7828
Description EIL family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sobic.001G387600.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1EIN3506.31.5e-154784671354
                           XXXXXXXXXXXXXXXXXXXXXXX..XXXXX......XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
                  EIN3   1 eelkkrmwkdqmllkrlkerkkqlledkeaa.....tgakksnksneqarrkkmsraQDgiLkYMlkemevcnaqGfvYgiipekgkpv 84 
                           eel++rmw+d+m+lkrl+e ++++ +d  a       g++k ++s+eqarrkkmsraQDgiLkYMlk+mevc+aqGfvYgiipekgkpv
  Sobic.001G387600.1.p  78 EELERRMWRDRMKLKRLRELQQSRGKDSIAGggglaDGSSKPRQSQEQARRKKMSRAQDGILKYMLKMMEVCRAQGFVYGIIPEKGKPV 166
                           8********************998877665588887889999*********************************************** PP

                           XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....XX----STTS-HHHHHHHHHHHSSSSSS-TTS--TTT--HHHH- CS
                  EIN3  85 egasdsLraWWkekvefdrngpaaiskyqaknlilsgesslqtersseshslselqDTtlgSLLsalmqhcdppqrrfplekgvepPWW 173
                           +gasd+LraWWkekv+fdrngpaai+kyqa+n++++ e++l t++ +++hsl+elqDTtlgSLLsalmqhcdppqrr+plekgv+pPWW
  Sobic.001G387600.1.p 167 SGASDNLRAWWKEKVRFDRNGPAAIAKYQADNAVPGAENEL-TSGAASPHSLQELQDTTLGSLLSALMQHCDPPQRRYPLEKGVPPPWW 254
                           *****************************************.55********************************************* PP

                           --S--HHHHHHT--TT--.-----GGG--HHHHHHHHHHHHHHTGGGHHHHHHTTTTSSSSTTT--SHHHHHHHHHHTTTTT-S--XXX CS
                  EIN3 174 PtGkelwwgelglskdqgtppykkphdlkkawkvsvLtavikhmsptieeirelerqskylqdkmsakesfallsvlnqeekecatvsa 262
                           PtG+e+ww+elg++kdqg+ppykkphdlkkawkvsvLtavikhmsp+ie+ir+l+rqsk+lqdkm+ake  ++l+v++qee+++ ++++
  Sobic.001G387600.1.p 255 PTGDEEWWPELGIPKDQGPPPYKKPHDLKKAWKVSVLTAVIKHMSPDIEKIRRLVRQSKCLQDKMTAKEISTWLAVVKQEEELYLKLHP 343
                           ***************************************************************************************** PP

                           X..XX.XXXX..XXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXX............................XXXXXXXXXXXXXXXX CS
                  EIN3 263 h..ss.slrk..qspkvtlsceqkedvegkkeskikhvqavktta............................gfpvvrkrkkkpsesa 318
                              ++ s+    ++ +++ s ++++dv+  +e k  ++ ++kt                              ++++++kr+++ + + 
  Sobic.001G387600.1.p 344 GalPPaSTGGiaSAISFNTS-SSEYDVDIIDECKGDEAGNQKTGVtdptafnlgaailsdkflvqtpmkeetaDVEFIQKRNAPAAAEP 431
                           98633333333244444444.5599***7777777888888777788999********************************9876655 PP

                           XXXXX......XXXXXXX.XXXXXXXXXXXXXXXXX CS
                  EIN3 319 kvsskevsrtcqssqfrgsetelifadknsisqney 354
                             + ++ ++tc++ q+++s+++ +f d+n +++++y
  Sobic.001G387600.1.p 432 ELMLNNRVYTCNNVQCPHSDYSYGFLDRNTRNSHQY 467
                           55555567**************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF048736.1E-13278335No hitNo description
Gene3DG3DSA:1.10.3180.101.4E-74209343IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
SuperFamilySSF1167682.09E-61214338IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0001666Biological Processresponse to hypoxia
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009873Biological Processethylene-activated signaling pathway
GO:0042742Biological Processdefense response to bacterium
GO:0071281Biological Processcellular response to iron ion
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 644 aa     Download sequence    Send to blast
MMGGGLMMDQ SVVFPGVHNF VDLLQQNGDK NLGFGSLMPQ TSSGDQCVMG EGDLVDPPPE  60
SFPDAGEDDS DDDVEDIEEL ERRMWRDRMK LKRLRELQQS RGKDSIAGGG GLADGSSKPR  120
QSQEQARRKK MSRAQDGILK YMLKMMEVCR AQGFVYGIIP EKGKPVSGAS DNLRAWWKEK  180
VRFDRNGPAA IAKYQADNAV PGAENELTSG AASPHSLQEL QDTTLGSLLS ALMQHCDPPQ  240
RRYPLEKGVP PPWWPTGDEE WWPELGIPKD QGPPPYKKPH DLKKAWKVSV LTAVIKHMSP  300
DIEKIRRLVR QSKCLQDKMT AKEISTWLAV VKQEEELYLK LHPGALPPAS TGGIASAISF  360
NTSSSEYDVD IIDECKGDEA GNQKTGVTDP TAFNLGAAIL SDKFLVQTPM KEETADVEFI  420
QKRNAPAAAE PELMLNNRVY TCNNVQCPHS DYSYGFLDRN TRNSHQYTCK YNEPIPQSTE  480
NKPPPAPPQS QAFQPAFNQP NQSLNNLDFS LPMDGQRSIA ELMNMYDNNF MTNKNMSSDS  540
VTIMERPNAM PQRIQMDEGF FGQGNGVFDD VNSMMQQQQQ APVQQQQQQQ QQQFFIRDDT  600
PFVSQMGDIT STSEFRFGSG FNMSSTVDYP GAAQKNDGTN WFY*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4zds_A1e-742123431132Protein ETHYLENE INSENSITIVE 3
4zds_B1e-742123431132Protein ETHYLENE INSENSITIVE 3
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Sbi.63170.0embryo| leaf| ovary| panicle| root
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots, leaf blades, leaf sheaths, stems, internodes, anthers of young flowers, and developing grains. {ECO:0000269|PubMed:25995326}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor acting as a positive regulator in the ethylene response pathway (PubMed:16786297, PubMed:28829777, PubMed:27701783, PubMed:25995326). Required for the inhibition of root growth by ethylene in etiolated seedlings (PubMed:25995326, PubMed:28829777). Functions upstream of the auxin biosynthetic gene YUCCA8 and directly activates its expression (PubMed:28829777). Functions downstream of the ethylene signaling factor EIN2 in disease resistance against the rice blast fungus (Magnaporthe oryzae) (PubMed:27701783). Binds directly to the promoters of the NADPH oxidases RBOHA and RBOHB, and the jasmonate biosynthetic gene OPR4 to activate their expression during fungal infection (PubMed:27701783). May enhance disease resistance by facilitating reactive oxygen species (ROS) generation and jasmonate biosynthesis with subsequent phytoalexin accumulation during Magnaporthe oryzae infection (PubMed:27701783). Acts as negative regulator of salt tolerance (PubMed:25995326). During salt stress, activates the cation transporter HKT1, which mediates increased sodium uptake in roots, and contributes to sodium accumulation and salt toxicity (PubMed:25995326). Binds directly to the DNA sequence 5'-TGTTACAAATACC-3' in the promoter of the GA20OX2 gene to activate its expression at the transcriptional level during ethylene signaling (PubMed:30002253). Possesses transactivation activity in protoplasts (PubMed:25995326). {ECO:0000269|PubMed:16786297, ECO:0000269|PubMed:25995326, ECO:0000269|PubMed:27701783, ECO:0000269|PubMed:28829777, ECO:0000269|PubMed:30002253}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00367DAPTransfer from AT3G20770Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapSobic.001G387600.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by infection with the fungal pathogen Magnaporthe oryzae. {ECO:0000269|PubMed:27701783}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKT1568450.0KT156845.1 Zea mays subsp. mays transcription factor EIL1 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002467935.10.0ETHYLENE INSENSITIVE 3-like 1 protein
RefseqXP_021317527.10.0ETHYLENE INSENSITIVE 3-like 1 protein
SwissprotQ10M410.0EIL1A_ORYSJ; Protein ETHYLENE-INSENSITIVE 3-like 1a
TrEMBLC5X1R50.0C5X1R5_SORBI; Uncharacterized protein
STRINGSb01g036740.10.0(Sorghum bicolor)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP63838168
Representative plantOGRP5631682
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G27050.11e-169ETHYLENE-INSENSITIVE3-like 1
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Yang C, et al.
    MAOHUZI6/ETHYLENE INSENSITIVE3-LIKE1 and ETHYLENE INSENSITIVE3-LIKE2 Regulate Ethylene Response of Roots and Coleoptiles and Negatively Affect Salt Tolerance in Rice.
    Plant Physiol., 2015. 169(1): p. 148-65
    [PMID:25995326]
  3. Yang C, et al.
    Activation of ethylene signaling pathways enhances disease resistance by regulating ROS and phytoalexin production in rice.
    Plant J., 2017. 89(2): p. 338-353
    [PMID:27701783]
  4. Qin H, et al.
    The activation of OsEIL1 on YUC8 transcription and auxin biosynthesis is required for ethylene-inhibited root elongation in rice early seedling development.
    PLoS Genet., 2017. 13(8): p. e1006955
    [PMID:28829777]
  5. Kuroha T, et al.
    Ethylene-gibberellin signaling underlies adaptation of rice to periodic flooding.
    Science, 2018. 361(6398): p. 181-186
    [PMID:30002253]