PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sobic.004G012100.1.p
Organism
Sorghum bicolor
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum
Family bHLH
Protein Properties Length: 232aa    MW: 25270.7 Da    PI: 6.2944
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sobic.004G012100.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH34.82.9e-1165112454
                           HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
                   HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                           ++  rE+ RRd++N++f eL +++ +    ++ Kl+Ka iL  A + + +L
  Sobic.004G012100.1.p  65 SKACREKMRRDKLNDRFLELSSVMNPG---KQAKLDKANILSDAARMVAQL 112
                           6789**********************9...9**************999888 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF474592.49E-1354128IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088812.32261112IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.61E-864117No hitNo description
PfamPF000101.0E-865112IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.106.9E-1366134IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003536.5E-867118IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 232 aa     Download sequence    Send to blast
MDCAVGGDPV EDFLLGGAGD DGDLAIFCDG GRLGIEGVNG DACGFDQSNL GKRGRDEPSS  60
SGPKSKACRE KMRRDKLNDR FLELSSVMNP GKQAKLDKAN ILSDAARMVA QLRGEAEKLK  120
ESNEKLRENI KDLKEEKNEL REEKVRLKVE KDRLEQQVKA MSVAPTGYVP HLPHPASYHP  180
AAFTPFVPPQ QAPANKSAPI PAAFPGMAMW QWLPPTIVDT TQDPKLWPPN A*
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Sbi.49780.0callus| embryo| leaf| pollen| root
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Widely expressed throughout development, mostly in vasculatures. {ECO:0000269|PubMed:17028341}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269|PubMed:17028341}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapSobic.004G012100.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKJ7280060.0KJ728006.1 Zea mays clone pUT6139 bHLH transcription factor (bHLH128) mRNA, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021314882.11e-170transcription factor ILR3-like isoform X1
SwissprotQ9FH378e-58ILR3_ARATH; Transcription factor ILR3
TrEMBLA0A194YM801e-169A0A194YM80_SORBI; Uncharacterized protein
STRINGSb04g001200.11e-169(Sorghum bicolor)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP81733646
Representative plantOGRP7551766
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G54680.11e-47bHLH family protein
Publications ? help Back to Top
  1. Li X,Zhang H,Ai Q,Liang G,Yu D
    Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana.
    Plant Physiol., 2016. 170(4): p. 2478-93
    [PMID:26921305]
  2. Aparicio F,Pallás V
    The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response.
    Mol. Plant Pathol., 2017. 18(2): p. 173-186
    [PMID:26929142]
  3. Liang G,Zhang H,Li X,Ai Q,Yu D
    bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana.
    J. Exp. Bot., 2017. 68(7): p. 1743-1755
    [PMID:28369511]
  4. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]
  5. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  6. Min JH, et al.
    Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element.
    Front Plant Sci, 2017. 8: p. 2100
    [PMID:29321786]
  7. Samira R, et al.
    The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis.
    Plant Mol. Biol., 2018. 97(4-5): p. 297-309
    [PMID:29882068]