PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sof000116
Organism
Saccharum officinarum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Saccharinae; Saccharum; Saccharum officinarum complex
Family EIL
Protein Properties Length: 382aa    MW: 43592 Da    PI: 5.6311
Description EIL family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Sof#S17444984PU_unrefUnigeneView CDS
PUT-157a-Saccharum_officinarum-520133734PU_refplantGDBView CDS
PUT-157a-Saccharum_officinarum-521133726PU_unrefplantGDBView CDS
PUT-157a-Saccharum_officinarum-53234PU_unrefplantGDBView CDS
PUT-157a-Saccharum_officinarum-53235PU_unrefplantGDBView CDS
PUT-157a-Saccharum_officinarum-53237PU_unrefplantGDBView CDS
PUT-157a-Saccharum_officinarum-53242PU_unrefplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1EIN3250.77.5e-77215057206
                XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....XX----STTS-HHHHHHHHHHHSSSSS CS
       EIN3  57 LkYMlkemevcnaqGfvYgiipekgkpvegasdsLraWWkekvefdrngpaaiskyqaknlilsgesslqtersseshslselqDTtlgSLLsalmqhcd 156
                Lk Ml +m++c+aqGfvYgiipekgkp   a  +LraWWkekv+fdrngpa i+ky a+n +++ e++l + + +++hsl+elqDTtlgSLLsalmqhcd
  Sof000116   2 LKSMLNMMHACRAQGFVYGIIPEKGKPRRRAFHNLRAWWKEKVRFDRNGPAVITKYHADNTVPGAENELAS-GAASPHSLQELQDTTLGSLLSALMQHCD 100
                9********************************************************************66.**************************** PP

                S-TTS--TTT--HHHH---S--HHHHHHT--TT--.-----GGG--HHHH CS
       EIN3 157 ppqrrfplekgvepPWWPtGkelwwgelglskdqgtppykkphdlkkawk 206
                p q+ +plekgv+pPWWPtG+e+ww+elg+++dqg+p+ykkphdlkkawk
  Sof000116 101 PAQQLYPLEKGVPPPWWPTGDEEWWPELGIPNDQGPPSYKKPHDLKKAWK 150
                *************************************************9 PP
2EIN326.51.1e-08155210299354
                XXXXXXXXXXXXXXXXXXXXXXXXX......XXXXXXX.XXXXXXXXXXXXXXXXX CS
       EIN3 299 kttagfpvvrkrkkkpsesakvsskevsrtcqssqfrgsetelifadknsisqney 354
                ++ta++++++kr+++ + +   + ++ ++tc++ q+++++++ +f d+n++++++y
  Sof000116 155 EETADVEFIQKRNAHVAAEPELMLNNRVYTCNNIQCPRNDYSYGFLDRNARNSHQY 210
                56789*******9987665555555567**************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF048736.5E-751151No hitNo description
Gene3DG3DSA:1.10.3180.101.8E-3972151IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
SuperFamilySSF1167685.75E-3377151IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 382 aa     Download sequence    Send to blast
MLKSMLNMMH ACRAQGFVYG IIPEKGKPRR RAFHNLRAWW KEKVRFDRNG PAVITKYHAD  60
NTVPGAENEL ASGAASPHSL QELQDTTLGS LLSALMQHCD PAQQLYPLEK GVPPPWWPTG  120
DEEWWPELGI PNDQGPPSYK KPHDLKKAWK TPMNEETADV EFIQKRNAHV AAEPELMLNN  180
RVYTCNNIQC PRNDYSYGFL DRNARNSHQY TCKYNDPIPQ STENKPPPPP PQSQAFQPAF  240
NQPNQALNNL DFSLPMDGQR SIAELMNMYD NNFMTNKNMS SDSVAIMERP NAMPQRIQMD  300
EGFFGQGNGV FDDVNSMMQQ QQQAPVQQQQ QQFFIRDDTP FVSQMGDITS TSXFRFGSGF  360
NMSNTVDYPS GAQKNDXDQW XY
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4zds_A9e-4075151177Protein ETHYLENE INSENSITIVE 3
4zds_B9e-4075151177Protein ETHYLENE INSENSITIVE 3
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Sof.179050.0bud| callus| crown| inflorescence| leaf| meristem| root| seed| stem
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots, leaf blades, leaf sheaths, stems, internodes, anthers of young flowers, and developing grains. {ECO:0000269|PubMed:25995326}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor acting as a positive regulator in the ethylene response pathway (PubMed:16786297, PubMed:28829777, PubMed:27701783, PubMed:25995326). Required for the inhibition of root growth by ethylene in etiolated seedlings (PubMed:25995326, PubMed:28829777). Functions upstream of the auxin biosynthetic gene YUCCA8 and directly activates its expression (PubMed:28829777). Functions downstream of the ethylene signaling factor EIN2 in disease resistance against the rice blast fungus (Magnaporthe oryzae) (PubMed:27701783). Binds directly to the promoters of the NADPH oxidases RBOHA and RBOHB, and the jasmonate biosynthetic gene OPR4 to activate their expression during fungal infection (PubMed:27701783). May enhance disease resistance by facilitating reactive oxygen species (ROS) generation and jasmonate biosynthesis with subsequent phytoalexin accumulation during Magnaporthe oryzae infection (PubMed:27701783). Acts as negative regulator of salt tolerance (PubMed:25995326). During salt stress, activates the cation transporter HKT1, which mediates increased sodium uptake in roots, and contributes to sodium accumulation and salt toxicity (PubMed:25995326). Binds directly to the DNA sequence 5'-TGTTACAAATACC-3' in the promoter of the GA20OX2 gene to activate its expression at the transcriptional level during ethylene signaling (PubMed:30002253). Possesses transactivation activity in protoplasts (PubMed:25995326). {ECO:0000269|PubMed:16786297, ECO:0000269|PubMed:25995326, ECO:0000269|PubMed:27701783, ECO:0000269|PubMed:28829777, ECO:0000269|PubMed:30002253}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by infection with the fungal pathogen Magnaporthe oryzae. {ECO:0000269|PubMed:27701783}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002467935.11e-131ETHYLENE INSENSITIVE 3-like 1 protein
RefseqXP_021317527.11e-131ETHYLENE INSENSITIVE 3-like 1 protein
SwissprotQ10M417e-92EIL1A_ORYSJ; Protein ETHYLENE-INSENSITIVE 3-like 1a
TrEMBLA0A2U8KGF71e-136A0A2U8KGF7_9POAL; Ethylene-insensitive-3 (Fragment)
STRINGOMERI03G14290.11e-138(Oryza meridionalis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G27050.11e-75ETHYLENE-INSENSITIVE3-like 1
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Yang C, et al.
    MAOHUZI6/ETHYLENE INSENSITIVE3-LIKE1 and ETHYLENE INSENSITIVE3-LIKE2 Regulate Ethylene Response of Roots and Coleoptiles and Negatively Affect Salt Tolerance in Rice.
    Plant Physiol., 2015. 169(1): p. 148-65
    [PMID:25995326]
  3. Yang C, et al.
    Activation of ethylene signaling pathways enhances disease resistance by regulating ROS and phytoalexin production in rice.
    Plant J., 2017. 89(2): p. 338-353
    [PMID:27701783]
  4. Qin H, et al.
    The activation of OsEIL1 on YUC8 transcription and auxin biosynthesis is required for ethylene-inhibited root elongation in rice early seedling development.
    PLoS Genet., 2017. 13(8): p. e1006955
    [PMID:28829777]
  5. Kuroha T, et al.
    Ethylene-gibberellin signaling underlies adaptation of rice to periodic flooding.
    Science, 2018. 361(6398): p. 181-186
    [PMID:30002253]