PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sof008459
Organism
Saccharum officinarum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Saccharinae; Saccharum; Saccharum officinarum complex
Family TALE
Protein Properties Length: 289aa    MW: 32660.1 Da    PI: 7.1696
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PUT-157a-Saccharum_officinarum-25167PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox27.26.5e-092162521955
                HHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS
   Homeobox  19 FeknrypsaeereeLAkklgLterqVkvWFqNrRake 55 
                 +k +yps++++  LA+++gL+ +q+ +WF N+R ++
  Sof008459 216 HYKWPYPSETQKVALAESTGLDLKQINNWFINQRKRH 252
                55779*****************************885 PP
2ELK37.55.1e-13172193122
        ELK   1 ELKhqLlrKYsgyLgsLkqEFs 22 
                ELKh+Ll+KYsgyL+sLkqE+s
  Sof008459 172 ELKHHLLKKYSGYLSSLKQELS 193
                9*******************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM012556.9E-193276IPR005540KNOX1
PfamPF037901.1E-203474IPR005540KNOX1
SMARTSM012561.0E-2783134IPR005541KNOX2
PfamPF037918.6E-2389132IPR005541KNOX2
SMARTSM0118857092112IPR005539ELK domain
PROSITE profilePS5121311.331172192IPR005539ELK domain
PfamPF037896.2E-10172193IPR005539ELK domain
SMARTSM011884.9E-7172193IPR005539ELK domain
PROSITE profilePS5007112.487192255IPR001356Homeobox domain
SuperFamilySSF466891.63E-19193267IPR009057Homeodomain-like
SMARTSM003894.2E-12194259IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.605.2E-28197257IPR009057Homeodomain-like
CDDcd000861.74E-11204256No hitNo description
PfamPF059205.0E-16212251IPR008422Homeobox KN domain
PROSITE patternPS000270230253IPR017970Homeobox, conserved site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 289 aa     Download sequence    Send to blast
QLANGGSLLD ACVNVKAKGE PSSSSPYAGD LEVIKAKIIS HPHYYSLLAA YLECKKVGAP  60
PEVSARLTAM AKELEARQRT ALGGLGAATE PELDQFMEAY HEMLVKFREE LTRPLQEAME  120
FMRRVESQLN SLSISGRSLR NILSSGSSEE DQEGSGGETE LPEVDVHGVD QELKHHLLKK  180
YSGYLSSLKQ ELSKKKKKGK LPKEARQQLL SWWDLHYKWP YPSETQKVAL AESTGLDLKQ  240
INNWFINQRK RHWKPSEEMH HLMMDGYHTT NAFYMDGHFI NDGGLYRLG
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Sof.38330.0bud| crown| inflorescence| leaf| meristem| seed| stem
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed throughout apical and vegetative meristem during development. Down-regulated as leaves and floral organs are initiated. {ECO:0000269|PubMed:1362381}.
UniprotTISSUE SPECIFICITY: Expressed in apical meristems of vegetative and floral stems as well as in the underlying ground meristem. Specifically expressed in vascular bundles developing both in the leaf and stem. Very low levels of expression in leaves.
Functional Description ? help Back to Top
Source Description
UniProtBinds to RNA (PubMed:17965274). Possible transcription factor that regulates genes involved in development. Mutations in KN-1 alter leaf development. Foci of cells along the lateral vein do not differentiate properly but continue to divide, forming knots. May participate in the switch from indeterminate to determinate cell fates. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269|PubMed:17965274}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002463952.10.0homeotic protein knotted-1
SwissprotP243450.0KN1_MAIZE; Homeotic protein knotted-1
TrEMBLA0A0B5GXC50.0A0A0B5GXC5_9POAL; Knotted1-like homeobox protein
STRINGSb01g009480.10.0(Sorghum bicolor)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G08150.11e-91KNOTTED-like from Arabidopsis thaliana
Publications ? help Back to Top
  1. Lowe B,Mathern J,Hake S
    Active Mutator elements suppress the knotted phenotype and increase recombination at the Kn1-O tandem duplication.
    Genetics, 1992. 132(3): p. 813-22
    [PMID:1334895]
  2. Sinha N,Hake S
    Mutant characters of knotted maize leaves are determined in the innermost tissue layers.
    Dev. Biol., 1990. 141(1): p. 203-10
    [PMID:2391001]
  3. Chen H,Jackson D,Kim JY
    Identification of evolutionarily conserved amino acid residues in homeodomain of KNOX proteins for intercellular trafficking.
    Plant Signal Behav, 2014. 9(3): p. e28355
    [PMID:24603432]
  4. Sinha NR,Williams RE,Hake S
    Overexpression of the maize homeo box gene, KNOTTED-1, causes a switch from determinate to indeterminate cell fates.
    Genes Dev., 1993. 7(5): p. 787-95
    [PMID:7684007]
  5. Greene B,Walko R,Hake S
    Mutator insertions in an intron of the maize knotted1 gene result in dominant suppressible mutations.
    Genetics, 1994. 138(4): p. 1275-85
    [PMID:7896105]
  6. Mathern J,Hake S
    Mu element-generated gene conversions in maize attenuate the dominant knotted phenotype.
    Genetics, 1997. 147(1): p. 305-14
    [PMID:9286690]