PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sof011111
Organism
Saccharum officinarum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Saccharinae; Saccharum; Saccharum officinarum complex
Family C2H2
Protein Properties Length: 242aa    MW: 28195.8 Da    PI: 8.5896
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PUT-157a-Saccharum_officinarum-133058PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H217.98.4e-061035123
               EEET..TTTEEESSHHHHHHHHHH.T CS
    zf-C2H2  1 ykCp..dCgksFsrksnLkrHirt.H 23
               ++C+   C+++Fs k n++rH +  H
  Sof011111 10 FSCTvdGCDRRFSMKANMQRHVKEiH 35
               8999******************9988 PP
2zf-C2H218.94.1e-064771123
               EEET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2  1 ykCp..dCgksFsrksnLkrHirtH 23
               + C+   C+k+F+ +s Lk+H  +H
  Sof011111 47 FICKeeGCNKVFKYSSKLKKHEESH 71
               789999***************9988 PP
3zf-C2H217.31.3e-05138162223
                EET..TTTEEESSHHHHHHHHHH.T CS
    zf-C2H2   2 kCp..dCgksFsrksnLkrHirt.H 23 
                kC+   C  sFs+ksnL++Hi+  H
  Sof011111 138 KCTfeGCEHSFSNKSNLTKHIKAcH 162
                79999*****************955 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576678.27E-8836No hitNo description
Gene3DG3DSA:3.30.160.604.8E-9837IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015711.7591040IPR007087Zinc finger, C2H2
SMARTSM003553.0E-41035IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002801235IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.9E-84071IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576673.86E-54472No hitNo description
PROSITE profilePS5015710.3054771IPR007087Zinc finger, C2H2
SMARTSM003550.00434771IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002804971IPR007087Zinc finger, C2H2
SMARTSM003556.179104IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028081104IPR007087Zinc finger, C2H2
SMARTSM0035512107128IPR015880Zinc finger, C2H2-like
SuperFamilySSF576673.75E-9122179No hitNo description
SMARTSM003550.034137162IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.552137167IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.608.0E-7138162IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280139162IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.604.6E-6163190IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.515168194IPR007087Zinc finger, C2H2
SMARTSM003550.91168194IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280170194IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 242 aa     Download sequence    Send to blast
XMLKHEGKLF SCTVDGCDRR FSMKANMQRH VKEIHEDENA SKSNQQFICK EEGCNKVFKY  60
SSKLKKHEES HVKLDYVEVL CGEPGCMKMF TNVEYLRAHN QSCHQYIQCE ICGEKHLKKN  120
IKRHLQSHDK VPSGERMKCT FEGCEHSFSN KSNLTKHIKA CHDQLKPFKC QIAGCGKAFT  180
YKHVRDNHEK SGAHVYIEGD FEEMDEQLRA RPRGGRKWKA LTVETLTRKR VTIXCETFIV  240
DE
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1210218RPRGGRKWK
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Sof.188190.0inflorescence| leaf| seed
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Both isoforms 1 and 2 transcripts are expressed in seedlings and both TFIIIA and TFIIIA-C are present at similar ratios in 10-day-old seedlings (at protein level). In correlation with the reorganization of 5S rDNA chromatin to a mature state, full-length isoform 1 protein TFIIIA with transcriptional activity accumulates and permits de novo transcription of 5S rRNA. Isoforms 1 and 2 transcripts accumulate in various tissues of the reproductive phase, including flowers and siliques, but only isoform 2 is present in mature seeds. In flowers, both TFIIIA and TFIIIA-C are present at similar ratios (at protein level). Very low amounts of TFIIIA are found in extracts from fresh siliques compared to TFIIIA-C. The amount of full-length TFIIIA protein progressively increases from fresh siliques to seeds concomitant with lower proportions of the shorter TFIIIA-C protein (at protein level) thus leading to 5S rRNA accumulation in the seed. {ECO:0000269|PubMed:22353599}.
UniprotTISSUE SPECIFICITY: Expressed in seedlings, flowers, siliques and seeds. {ECO:0000269|PubMed:22353599}.
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021301991.11e-166transcription factor IIIA isoform X2
SwissprotQ84MZ44e-80TF3A_ARATH; Transcription factor IIIA
TrEMBLA0A1Z5R4A51e-160A0A1Z5R4A5_SORBI; Uncharacterized protein
STRINGSi020193m1e-142(Setaria italica)
STRINGGRMZM2G380515_P021e-146(Zea mays)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G72050.12e-83transcription factor IIIA