PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Sopen06g030430.2

Organism

Solanum pennellii

Taxonomic ID

28526

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon

Family

E2F/DP

Protein Properties

Length: 363aa MW: 40318.9 Da PI: 4.2715

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sopen06g030430.2	genome	spenn	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	72.6	4.4e-23	43	106	3	71
E2F_TDP 3 eksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 ++sL+ lt+kf++l+++se+g+++ln++a++L +v k+RR+YD++ VLe+++liekk+ n i+wkg Sopen06g030430.2 43 DNSLGFLTKKFINLIKHSEDGVLDLNKAADTL---EV--KKRRLYDVTSVLEGIGLIEKKSLNMIQWKG 106 89****************************...99..9*************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	3.6E-25	40	108	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	1.4E-30	41	106	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	3.26E-16	42	104	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	7.3E-22	43	106	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	1.02E-41	117	223	No hit	No description
SuperFamily	SSF144074	6.28E-30	119	223	No hit	No description
Pfam	PF16421	2.1E-28	122	221	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 363 aa Download sequence Send to blast
MQTPISGKAG KSQKAPKSSA QATSSLGFRS GNNVTPVGPC CYDNSLGFLT KKFINLIKHS 60 EDGVLDLNKA ADTLEVKKRR LYDVTSVLEG IGLIEKKSLN MIQWKGLDVS RPGEVDESVT 120 SLQAEVENLT IEESILDEQI REKQERLRVL SEDENNQRWL FVTEDDIKSL PCLQNYTLIA 180 IRFPHGTSLE VPDPNEAVDY PQRRYSIVIR STMGPIDVYL ISKFEEKFKQ ITTVEEPSTM 240 PSTSGFIEKE TAALPVDDGR GVGVGMEEQE NQRECPDAGT SQNPVSGIIK IVPDFDPLQN 300 QEEDYLFLSD ANVSNTDMWT ESVRDALDSI YEDYSIADVR SPHAQTPPSS TTELTSANTT 360 EAE

Sequence ? help Back to Top

Protein Sequence Length: 363 aa Download sequence Send to blast

MQTPISGKAG KSQKAPKSSA QATSSLGFRS GNNVTPVGPC CYDNSLGFLT KKFINLIKHS  60
EDGVLDLNKA ADTLEVKKRR LYDVTSVLEG IGLIEKKSLN MIQWKGLDVS RPGEVDESVT  120
SLQAEVENLT IEESILDEQI REKQERLRVL SEDENNQRWL FVTEDDIKSL PCLQNYTLIA  180
IRFPHGTSLE VPDPNEAVDY PQRRYSIVIR STMGPIDVYL ISKFEEKFKQ ITTVEEPSTM  240
PSTSGFIEKE TAALPVDDGR GVGVGMEEQE NQRECPDAGT SQNPVSGIIK IVPDFDPLQN  300
QEEDYLFLSD ANVSNTDMWT ESVRDALDSI YEDYSIADVR SPHAQTPPSS TTELTSANTT  360
EAE

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	3e-23	36	107	2	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027773767.1	0.0	transcription factor E2FB-like
Swissprot	Q9FV71	1e-115	E2FB_ARATH; Transcription factor E2FB
TrEMBL	A0A3Q7H2M1	0.0	A0A3Q7H2M1_SOLLC; Uncharacterized protein
STRING	Solyc06g074010.2.1	0.0	(Solanum lycopersicum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1077	24	84

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G22220.3	1e-119	E2F transcription factor 1

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]