PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Sopim01g007760.0.1

Organism

Solanum pimpinellifolium

Taxonomic ID

4084

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon

Family

E2F/DP

Protein Properties

Length: 480aa MW: 52584.5 Da PI: 4.7313

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sopim01g007760.0.1	genome	CSHL	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	86.3	2.3e-27	156	221	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+g+++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg Sopim01g007760.0.1 156 RYDSSLGLLTKKFINLIKHAEDGMLDLNQAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 221 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.4E-29	154	223	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	2.54E-17	156	219	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	1.6E-34	156	221	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	1.4E-24	158	221	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	8.65E-48	232	338	No hit	No description
SuperFamily	SSF144074	3.14E-33	235	338	No hit	No description
Pfam	PF16421	2.7E-33	237	336	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 480 aa Download sequence Send to blast
MTGSSASTGG AAPPTAQSSS AVVNGGGRSQ ISHPIKRYLP FASMRPPFVT PEDYHRFSIP 60 GVDSRIGSAS LQPEAIVVKS PALKRKTGYI KEVESSDWTA NSGYADVANS PLGTPVSGKG 120 GRAHGRSRAT KNNKSGPQTP VYNAGSPSPL TPASCRYDSS LGLLTKKFIN LIKHAEDGML 180 DLNQAADTLE VQKRRIYDIT NVLEGIGLIE KKLKNRIQWK GVESSRPGEV DNDASILKAE 240 TDRLSVEERR LDERIREMQE KLRDMSEDEN NQRWLFVTEE DIKSLPCFQN ETLIAVKAPH 300 GTTLEVPDPD EAVDYPQRRY RIILRSTMGP IDVYLVSQFE EKFEEMNGVE PPTTIPVASS 360 SGSKDYPTME ISTVSNSVTE NEGQTHNVDQ LSSDLGTSQE YNGGMMKILP SDVDNDSDYW 420 LLSDANVSIT DMWKTDSTVE WDGETLLHDF GIDDLGTPRA HTPPSTNADV PDPMNVPPR*

Sequence ? help Back to Top

Protein Sequence Length: 480 aa Download sequence Send to blast

MTGSSASTGG AAPPTAQSSS AVVNGGGRSQ ISHPIKRYLP FASMRPPFVT PEDYHRFSIP  60
GVDSRIGSAS LQPEAIVVKS PALKRKTGYI KEVESSDWTA NSGYADVANS PLGTPVSGKG  120
GRAHGRSRAT KNNKSGPQTP VYNAGSPSPL TPASCRYDSS LGLLTKKFIN LIKHAEDGML  180
DLNQAADTLE VQKRRIYDIT NVLEGIGLIE KKLKNRIQWK GVESSRPGEV DNDASILKAE  240
TDRLSVEERR LDERIREMQE KLRDMSEDEN NQRWLFVTEE DIKSLPCFQN ETLIAVKAPH  300
GTTLEVPDPD EAVDYPQRRY RIILRSTMGP IDVYLVSQFE EKFEEMNGVE PPTTIPVASS  360
SGSKDYPTME ISTVSNSVTE NEGQTHNVDQ LSSDLGTSQE YNGGMMKILP SDVDNDSDYW  420
LLSDANVSIT DMWKTDSTVE WDGETLLHDF GIDDLGTPRA HTPPSTNADV PDPMNVPPR*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	8e-26	149	222	2	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC239738	1e-133	AC239738.5 Solanum lycopersicum strain Heinz 1706 chromosome 1 clone hba-240p19 map 1, complete sequence.
GenBank	HG975513	1e-133	HG975513.1 Solanum lycopersicum chromosome ch01, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004228901.1	0.0	transcription factor E2FA isoform X2
Swissprot	Q9FNY0	1e-164	E2FA_ARATH; Transcription factor E2FA
TrEMBL	A0A3Q7E8M0	0.0	A0A3Q7E8M0_SOLLC; Uncharacterized protein
STRING	Solyc01g007760.2.1	0.0	(Solanum lycopersicum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1077	24	84

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	1e-168	E2F transcription factor 3

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]