PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sp_114680_uppe.t1
Common NameSOVF_114680
Organism
Spinacia oleracea
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Caryophyllales; Chenopodiaceae; Chenopodioideae; Anserineae; Spinacia
Family E2F/DP
Protein Properties Length: 369aa    MW: 41647.1 Da    PI: 9.5388
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sp_114680_uppe.t1genomeTBVRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP74.79.8e-242287171
            E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                       rk+ksL+ll++kfl+l+ +   + + l+++a++L    v  +rRRiYDi+NVLe+++++++k+kn+++wkg
  Sp_114680_uppe.t1 22 RKQKSLGLLCSKFLNLYDRDGVESIGLDDAASKL---GV--ERRRIYDIVNVLESVGVLARKAKNQYTWKG 87
                       79*****************999************...**..****************************98 PP
2E2F_TDP77.31.4e-24151231171
            E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                        r+eksL+lltq+f+kl+ +s+ + ++l+e+ak L+ +      +++k+RR+YDi+NVL++++liek     ++k+++rw g
  Sp_114680_uppe.t1 151 RREKSLGLLTQNFVKLFICSNVDLISLEEAAKILLGDghnsiVMRTKVRRLYDIANVLSSMQLIEKtqqteTRKPAFRWLG 231
                        689**************************************999**********************9999999******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.106.0E-271888IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467859.07E-162185IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013724.7E-282287IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.1E-202387IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.109.6E-23147232IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.4E-30151231IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.01E-13153232IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023192.3E-19153231IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 369 aa     Download sequence    Send to blast
MAASPPSSAP EGSEDMRRKY SRKQKSLGLL CSKFLNLYDR DGVESIGLDD AASKLGVERR  60
RIYDIVNVLE SVGVLARKAK NQYTWKGFKG IPKALAALKE EGLRENFGSA SGSGKMKFHV  120
FDDEEDENSN PDTGSQPELP NSNVNSKPDN RREKSLGLLT QNFVKLFICS NVDLISLEEA  180
AKILLGDGHN SIVMRTKVRR LYDIANVLSS MQLIEKTQQT ETRKPAFRWL GLSERKEVAL  240
YNLPMSIDTK KRTFGTDVTN ISFKRNKDAF PAEEEGKPLK LHVKTENVEF PTEQNARPRS  300
YQYGPFAPVT VAKAGDQKNT KRVHDLESLA SVYRPLYQNQ ALRDLFDHYT EAWRSWYSEV  360
AGKSLEQVS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A1e-42212233228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021837168.10.0E2F transcription factor-like E2FE isoform X1
SwissprotQ8LSZ41e-125E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A0K9R2D50.0A0A0K9R2D5_SPIOL; Uncharacterized protein
STRINGXP_010678681.10.0(Beta vulgaris)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-127DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]