PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Sp_176650_ikao.t1

Common Name

SOVF_176650

Organism

Spinacia oleracea

Taxonomic ID

3562

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Caryophyllales; Chenopodiaceae; Chenopodioideae; Anserineae; Spinacia

Family

C2H2

Protein Properties

Length: 225aa MW: 25991.2 Da PI: 5.2696

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sp_176650_ikao.t1	genome	TBVR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.9	8.3e-06	10	34	1	23
EEET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirtH 23 + Cp dCgk++ + + Lk+Hi +H Sp_176650_ikao.t1 10 HICPysDCGKRYAHEYKLKNHIASH 34 68*********************96 PP
2	zf-C2H2	16.3	2.7e-05	71	96	1	23
EEET..TTTEEESSHHHHHHHHHH.T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt.H 23 ++Cp C+k + + + L+ H+r+ H Sp_176650_ikao.t1 71 FTCPyeGCDKAYIHEYKLNLHLRReH 96 89**********************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	2.66E-6	1	36	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.1E-8	1	36	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	9.494	10	39	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0041	10	34	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	12	35	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	4.36E-6	65	94	No hit	No description
Gene3D	G3DSA:3.30.160.60	6.7E-9	66	94	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	9.827	71	101	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0034	71	96	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	73	96	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 225 aa Download sequence Send to blast
MKTHSQENYH ICPYSDCGKR YAHEYKLKNH IASHHEKNSA EVPKYTPPVE KPVKTPKAAS 60 GTYSASSDRP FTCPYEGCDK AYIHEYKLNL HLRREHPGHY AEENAKTPQA NNVDHEMDEA 120 SDQDAYANKR SSWKSLKQSR PKPNLKLPPS KMSQRKGSGV SPAKVNIVKK PWQIKGETEY 180 DVKGETEYDE EDSEETEEDR DNVEDGRRYR ENNDDDDDEE TEDED

Functional Description ? help Back to Top
Source	Description
UniProt	Dual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269\|PubMed:22508367, ECO:0000269\|PubMed:24451981, ECO:0000269\|PubMed:26961720}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269\|PubMed:26961720}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021864252.1	1e-164	zinc finger transcription factor YY1
Swissprot	Q2V3L3	5e-70	YY1_ARATH; Zinc finger transcription factor YY1
TrEMBL	A0A0K9QI60	1e-165	A0A0K9QI60_SPIOL; Uncharacterized protein
STRING	XP_010670021.1	6e-97	(Beta vulgaris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G06634.2	3e-61	C2H2 family protein

Publications ? help Back to Top
Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4. DNA Res., 2001. 8(6): p. 285-90 [PMID:11853315] Li T,Wu XY,Li H,Song JH,Liu JY A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network. Mol Plant, 2016. 9(5): p. 650-661 [PMID:26961720] Wu XY,Li T A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response. Front Plant Sci, 2017. 8: p. 323 [PMID:28348572]