PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID TRIUR3_19744-P1
Organism
Triticum urartu
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Triticum
Family E2F/DP
Protein Properties Length: 358aa    MW: 40442.6 Da    PI: 6.9034
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
TRIUR3_19744-P1genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP56.54.6e-182077971
          E2F_TDP  9 ltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                     l  +f++l+ + + ++v l+++a++L    v  +rRRiYDi+NVLe+++++ +++kn+++w+g
  TRIUR3_19744-P1 20 LVASFVALYDRDDVETVGLDDAARRL---GV--ERRRIYDIVNVLESVGILVRRAKNRYTWIG 77
                     6789******9999************...**..****************************98 PP
2E2F_TDP79.14.1e-25136216171
          E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                      rkeksL+lltq+f+kl+ + e ++v+l+e+a+ L+ e     ++++k+RR+YDi+NVL++lnliek     ++k+++rw g
  TRIUR3_19744-P1 136 RKEKSLGLLTQNFVKLFLTMEVETVSLDEAARLLLGErhaesNMRTKVRRLYDIANVLSSLNLIEKtqqvdSRKPAFRWLG 216
                      79****************************************************************9999999******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM013726.5E-201277IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.27E-141476IPR011991Winged helix-turn-helix DNA-binding domain
Gene3DG3DSA:1.10.10.104.3E-191978IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023194.8E-162177IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.102.5E-23133217IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.4E-32136216IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.2E-20137216IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467858.3E-13138216IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 358 aa     Download sequence    Send to blast
MKHLTFASGR EGIDNPFIAL VASFVALYDR DDVETVGLDD AARRLGVERR RIYDIVNVLE  60
SVGILVRRAK NRYTWIGFEG VPAALKELKV SDDEDDDDKL GDAEGDADSE KLSQSIDNAS  120
DKPDTPMCPR RSVDHRKEKS LGLLTQNFVK LFLTMEVETV SLDEAARLLL GERHAESNMR  180
TKVRRLYDIA NVLSSLNLIE KTQQVDSRKP AFRWLGQAKR KEGATVTVAL PPARKIMSSK  240
RAFGTDITNI DNKRGKLVLE TENKPKLMQG GSSMLKTFES QLGQGKSSGF VYGPFHPAGA  300
RKHEVDDQSV RENETKNIQD WENLAVSFRP QYQNHALNDL FGHYVEAWKS WYLDLTRE
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A3e-333620832228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK3753580.0AK375358.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv3092B12.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020187543.10.0E2F transcription factor-like E2FE isoform X1
SwissprotQ8LSZ48e-94E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLM7Z6P70.0M7Z6P7_TRIUA; E2F transcription factor-like E2FE
STRINGTRIUR3_19744-P10.0(Triticum urartu)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP31853884
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-94DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]