PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thecc1EG000838t1
Common NameTCM_000838
Organism
Theobroma cacao
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma
Family GRF
Protein Properties Length: 632aa    MW: 67459 Da    PI: 7.4802
Description GRF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thecc1EG000838t1genomeCGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRC76.52.7e-24242286145
               WRC   1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkskee 45 
                       d+epgrCrRtDGKkWRCsr++++++k+CErH++rgr+rsrk++e 
  Thecc1EG000838t1 242 DPEPGRCRRTDGKKWRCSRDAVADQKYCERHINRGRHRSRKPVEG 286
                       79****************************************985 PP
2QLQ56.96.5e-20172208137
               QLQ   1 saFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiqk 37 
                       ++FT++Q+ +L++Q+l+yKy+ an+PvP++Ll a++k
  Thecc1EG000838t1 172 GPFTPSQWIELEHQALIYKYITANVPVPSNLLIALKK 208
                       59******************************99975 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM009512.6E-11172208IPR014978Glutamine-Leucine-Glutamine, QLQ
PfamPF088805.7E-14173206IPR014978Glutamine-Leucine-Glutamine, QLQ
PROSITE profilePS5166622.282173208IPR014978Glutamine-Leucine-Glutamine, QLQ
PROSITE profilePS5166725.287242286IPR014977WRC domain
PfamPF088798.2E-21243285IPR014977WRC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009624Biological Processresponse to nematode
GO:0048364Biological Processroot development
GO:0048366Biological Processleaf development
GO:0061062Biological Processregulation of nematode larval development
GO:0005634Cellular Componentnucleus
GO:0005524Molecular FunctionATP binding
Sequence ? help Back to Top
Protein Sequence    Length: 632 aa     Download sequence    Send to blast
MDFGVLGLEG IVGPDNGAPF QTQLPPPPLL SAEAKPKLLG SGFTKQERSS DSAEDHCKSS  60
KLPRTDDLPT PKTMPLHQGT PLLRSNSLVS ADTSHQEHML SFSSLKSEVP FISKDVGFVE  120
RSTQNSGFSY YQHTPSTYTR NAGELTLQCL VSGYGSGSLN ASMHGPLTGV RGPFTPSQWI  180
ELEHQALIYK YITANVPVPS NLLIALKKTL YPYGLSSSSA GSLPPNSLGW GSFHLGYASN  240
TDPEPGRCRR TDGKKWRCSR DAVADQKYCE RHINRGRHRS RKPVEGQTGH AASGTTNSKV  300
VPMSSSMSAS VITSGGASNS LAIAQQHQLK NLQSGAANPS ADTLVNRLFL NKEDVHGRVQ  360
DPRGLPMMSS STNLKSNGST FTVTKQGIPF AESSQSVFGH VASDSLVNPS HRSSYINSKE  420
YGAFLDFSNQ ETQDENPLRQ FIDDWPKDQS SSSVITWPEE LKSDWTQLSM SIPMASSEFS  480
SSSSSPAQEK LALSPLRLSR EFDPIQMGLG VNSDISDQNH KQANWIPISW GSSMGGPLGE  540
VLTHTTSNVG SCKNSSALSL LSEGWDGSPQ LGSSPTGVLQ KAPFGSLSNS SSGSSPIAEN  600
KKPHGGGSLC DDVLGSTLVS SASIPSVIRS L*
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. microRNA396-GRF1/GRF3 regulatory module acts as a developmental regulator in the reprogramming of root cells during cyst nematode infection, leading to the formation of the syncytium. {ECO:0000269|PubMed:12974814, ECO:0000269|PubMed:15326298, ECO:0000269|PubMed:22419826, ECO:0000269|PubMed:22751317}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: microRNA 396 (miR396a or miR396b) negatively regulates growth-regulating factors (GRF1-4 and GRF7-9). Up-regulated in response to cyst nematode infection. {ECO:0000269|PubMed:15200956, ECO:0000269|PubMed:19453503, ECO:0000269|PubMed:20023165, ECO:0000269|PubMed:22419826}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017969715.10.0PREDICTED: growth-regulating factor 1 isoform X1
SwissprotO810011e-136GRF1_ARATH; Growth-regulating factor 1
TrEMBLA0A061DH450.0A0A061DH45_THECC; Growth-regulating factor 1, putative isoform 1
STRINGEOX917540.0(Theobroma cacao)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM14542886
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G22840.11e-116growth-regulating factor 1
Publications ? help Back to Top
  1. Motamayor JC, et al.
    The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color.
    Genome Biol., 2013. 14(6): p. r53
    [PMID:23731509]
  2. Casadevall R,Rodriguez RE,Debernardi JM,Palatnik JF,Casati P
    Repression of growth regulating factors by the microRNA396 inhibits cell proliferation by UV-B radiation in Arabidopsis leaves.
    Plant Cell, 2013. 25(9): p. 3570-83
    [PMID:24076976]
  3. Liu J,Rice JH,Chen N,Baum TJ,Hewezi T
    Synchronization of developmental processes and defense signaling by growth regulating transcription factors.
    PLoS ONE, 2014. 9(5): p. e98477
    [PMID:24875638]
  4. Cao Y,Han Y,Jin Q,Lin Y,Cai Y
    Comparative Genomic Analysis of the GRF Genes in Chinese Pear (Pyrus bretschneideri Rehd), Poplar (Populous), Grape (Vitis vinifera), Arabidopsis and Rice (Oryza sativa).
    Front Plant Sci, 2016. 7: p. 1750
    [PMID:27933074]