PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Thecc1EG000838t2

Common Name

TCM_000838

Organism

Theobroma cacao

Taxonomic ID

3641

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma

Family

GRF

Protein Properties

Length: 511aa MW: 54021.3 Da PI: 8.7529

Description

GRF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thecc1EG000838t2	genome	CGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRC	76.9	2e-24	232	276	1	45
WRC 1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkskee 45 d+epgrCrRtDGKkWRCsr++++++k+CErH++rgr+rsrk++e Thecc1EG000838t2 232 DPEPGRCRRTDGKKWRCSRDAVADQKYCERHINRGRHRSRKPVEG 276 79****************************************985 PP
2	QLQ	57.2	5e-20	162	198	1	37
QLQ 1 saFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiqk 37 ++FT++Q+ +L++Q+l+yKy+ an+PvP++Ll a++k Thecc1EG000838t2 162 GPFTPSQWIELEHQALIYKYITANVPVPSNLLIALKK 198 59******************************99975 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00951	2.6E-11	162	198	IPR014978	Glutamine-Leucine-Glutamine, QLQ
Pfam	PF08880	4.4E-14	163	196	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51666	22.282	163	198	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51667	25.287	232	276	IPR014977	WRC domain
Pfam	PF08879	6.3E-21	233	275	IPR014977	WRC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009624	Biological Process	response to nematode
GO:0048364	Biological Process	root development
GO:0048366	Biological Process	leaf development
GO:0061062	Biological Process	regulation of nematode larval development
GO:0005634	Cellular Component	nucleus
GO:0005524	Molecular Function	ATP binding

Sequence ? help Back to Top
Protein Sequence Length: 511 aa Download sequence Send to blast
MDFGVLGLEG IVGPDNGAPF QTQLPPPPLL SAEAKPKLLG SGFTKQERSS DSAEDHCKSS 60 KLPRTDDLPT PKTMPLHQGT PLLRSNSLVS ADTSHQEHML SFSSLKSEVP FISKDVGFVE 120 RSTQNSGFSY YQHTPSTYTR NAGYGSGSLN ASMHGPLTGV RGPFTPSQWI ELEHQALIYK 180 YITANVPVPS NLLIALKKTL YPYGLSSSSA GSLPPNSLGW GSFHLGYASN TDPEPGRCRR 240 TDGKKWRCSR DAVADQKYCE RHINRGRHRS RKPVEGQTGH AASGTTNSKV VPMSSSMSAS 300 VITSGGASNS LAIAQQHQLK NLQSGAANPS ADTLVNRLFL NKEDTQLSMS IPMASSEFSS 360 SSSSPAQEKL ALSPLRLSRE FDPIQMGLGV NSDISDQNHK QANWIPISWG SSMGGPLGEV 420 LTHTTSNVGS CKNSSALSLL SEGWDGSPQL GSSPTGVLQK APFGSLSNSS SGSSPIAENK 480 KPHGGGSLCD DVLGSTLVSS ASIPSVIRSL *

Sequence ? help Back to Top

Protein Sequence Length: 511 aa Download sequence Send to blast

MDFGVLGLEG IVGPDNGAPF QTQLPPPPLL SAEAKPKLLG SGFTKQERSS DSAEDHCKSS  60
KLPRTDDLPT PKTMPLHQGT PLLRSNSLVS ADTSHQEHML SFSSLKSEVP FISKDVGFVE  120
RSTQNSGFSY YQHTPSTYTR NAGYGSGSLN ASMHGPLTGV RGPFTPSQWI ELEHQALIYK  180
YITANVPVPS NLLIALKKTL YPYGLSSSSA GSLPPNSLGW GSFHLGYASN TDPEPGRCRR  240
TDGKKWRCSR DAVADQKYCE RHINRGRHRS RKPVEGQTGH AASGTTNSKV VPMSSSMSAS  300
VITSGGASNS LAIAQQHQLK NLQSGAANPS ADTLVNRLFL NKEDTQLSMS IPMASSEFSS  360
SSSSPAQEKL ALSPLRLSRE FDPIQMGLGV NSDISDQNHK QANWIPISWG SSMGGPLGEV  420
LTHTTSNVGS CKNSSALSLL SEGWDGSPQL GSSPTGVLQK APFGSLSNSS SGSSPIAENK  480
KPHGGGSLCD DVLGSTLVSS ASIPSVIRSL *

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. {ECO:0000269\|PubMed:12974814, ECO:0000269\|PubMed:15326298, ECO:0000269\|PubMed:20023165, ECO:0000269\|PubMed:21036927}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: microRNA 396 (miR396a or miR396b) negatively regulates growth-regulating factors (GRF1-4 and GRF7-9). {ECO:0000269\|PubMed:15200956, ECO:0000269\|PubMed:19453503, ECO:0000269\|PubMed:20023165}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017969715.1	0.0	PREDICTED: growth-regulating factor 1 isoform X1
Refseq	XP_017969716.1	0.0	PREDICTED: growth-regulating factor 1 isoform X2
Swissprot	Q8L8A8	1e-96	GRF2_ARATH; Growth-regulating factor 2
TrEMBL	A0A061DH95	0.0	A0A061DH95_THECC; Growth-regulating factor 1, putative isoform 2
STRING	EOX91754	0.0	(Theobroma cacao)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22840.1	3e-68	growth-regulating factor 1

Link Out ? help Back to Top
Phytozome	Thecc1EG000838t2
Entrez Gene	18611328

Publications ? help Back to Top
Motamayor JC, et al. The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color. Genome Biol., 2013. 14(6): p. r53 [PMID:23731509] Casadevall R,Rodriguez RE,Debernardi JM,Palatnik JF,Casati P Repression of growth regulating factors by the microRNA396 inhibits cell proliferation by UV-B radiation in Arabidopsis leaves. Plant Cell, 2013. 25(9): p. 3570-83 [PMID:24076976] Liu J,Rice JH,Chen N,Baum TJ,Hewezi T Synchronization of developmental processes and defense signaling by growth regulating transcription factors. PLoS ONE, 2014. 9(5): p. e98477 [PMID:24875638] Cao Y,Han Y,Jin Q,Lin Y,Cai Y Comparative Genomic Analysis of the GRF Genes in Chinese Pear (Pyrus bretschneideri Rehd), Poplar (Populous), Grape (Vitis vinifera), Arabidopsis and Rice (Oryza sativa). Front Plant Sci, 2016. 7: p. 1750 [PMID:27933074]