PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thecc1EG006252t1
Common NameTCM_006252
Organism
Theobroma cacao
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma
Family C2H2
Protein Properties Length: 372aa    MW: 42723.6 Da    PI: 6.3814
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thecc1EG006252t1genomeCGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.30.000579101323
                       ET..TTTEEESSHHHHHHHHHHT CS
           zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                       C+   Cgk+F +   L++H   H
  Thecc1EG006252t1  79 CSyeGCGKTFIDAGALRKHSHIH 101
                       77779**************7766 PP
2zf-C2H217.31.4e-05106130123
                       EEET..TTTEEESSHHHHHHHHHHT CS
           zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                       y+C+   Cgk F ++s LkrH   H
  Thecc1EG006252t1 106 YVCHweGCGKKFLDSSKLKRHFLIH 130
                       9********************8877 PP
3zf-C2H220.71.1e-06136160123
                       EEET..TTTEEESSHHHHHHHHHHT CS
           zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                       + Cp   Cgk Fs   nL++H++tH
  Thecc1EG006252t1 136 FICPheGCGKAFSLDFNLRSHMKTH 160
                       78**********************9 PP
4zf-C2H217.89.4e-06166190123
                       EEET..TTTEEESSHHHHHHHHHHT CS
           zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                       + Cp  dCgk++ + + Lk+Hi +H
  Thecc1EG006252t1 166 HICPypDCGKRYAHEYKLKNHIASH 190
                       679999*****************96 PP
5zf-C2H215.26e-05229254123
                       EEET..TTTEEESSHHHHHHHHHH.T CS
           zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                       y+Cp   C k + + + Lk H+r+ H
  Thecc1EG006252t1 229 YVCPyeGCEKAYIHEYKLKLHLRReH 254
                       99**********************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.609.2E-1472103IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.003277101IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.78377106IPR007087Zinc finger, C2H2
PROSITE patternPS00028079101IPR007087Zinc finger, C2H2
SuperFamilySSF576674.26E-880130No hitNo description
Gene3DG3DSA:3.30.160.601.7E-14104126IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0011106130IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015713.921106135IPR007087Zinc finger, C2H2
PROSITE patternPS000280108130IPR007087Zinc finger, C2H2
SuperFamilySSF576675.33E-13121163No hitNo description
Gene3DG3DSA:3.30.160.605.9E-20127160IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003553.9E-4136160IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.591136165IPR007087Zinc finger, C2H2
PROSITE patternPS000280138160IPR007087Zinc finger, C2H2
SuperFamilySSF576673.72E-8152192No hitNo description
Gene3DG3DSA:3.30.160.603.4E-9161192IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0028166190IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.494166195IPR007087Zinc finger, C2H2
PROSITE patternPS000280168191IPR007087Zinc finger, C2H2
SuperFamilySSF576671.23E-5224252No hitNo description
Gene3DG3DSA:3.30.160.608.1E-10224252IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0047229254IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.868229259IPR007087Zinc finger, C2H2
PROSITE patternPS000280231254IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 372 aa     Download sequence    Send to blast
MEMQFPHNLF ERRPIFKSRA PAVKWFKEWV PQDVVATGGK CMILKWVNEN TLKALKEKEK  60
EPEAPEPEPE PTTEVLFLCS YEGCGKTFID AGALRKHSHI HGERQYVCHW EGCGKKFLDS  120
SKLKRHFLIH TGERDFICPH EGCGKAFSLD FNLRSHMKTH SQENYHICPY PDCGKRYAHE  180
YKLKNHIASH HEKNTTADVP KYATPTEKIT KTPKPSGGAY GSASSDRPYV CPYEGCEKAY  240
IHEYKLKLHL RREHPGHMSD ENVENATPNA DNEMDEASDQ DAYAGKRVNG KSQKQQSRAK  300
PNVKMPPAKI ARQKGSSPVT LPVPKKQWPV KEEVYEEEDS EETEEDRENV EDGWRYADNN  360
EDDDEETEYE D*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C4e-35791908119PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_007041332.10.0PREDICTED: uncharacterized zinc finger protein At4g06634 isoform X2
SwissprotQ2V3L31e-159YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A061E4L40.0A0A061E4L4_THECC; Zinc finger family protein isoform 1
STRINGEOX971630.0(Theobroma cacao)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM58592846
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.11e-144C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Motamayor JC, et al.
    The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color.
    Genome Biol., 2013. 14(6): p. r53
    [PMID:23731509]
  3. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  4. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]