PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thhalv10007566m
Common NameEUTSA_v10007566mg
Organism
Eutrema salsugineum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema
Family bHLH
Protein Properties Length: 466aa    MW: 50941.1 Da    PI: 6.0687
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thhalv10007566mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH361.3e-11285327754
                      HHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS
              HLH   7 erErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54 
                      ++ErrRR+++N+++  Lr+++Pk +      K++ a+iL  A++Y+k+L
  Thhalv10007566m 285 MAERRRRKKLNDRLYMLRSVVPKiS------KMDRASILGDAIDYLKEL 327
                      79*********************66......****************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088815.866278327IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474596.67E-17281351IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003534.2E-14284333IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000103.0E-9284327IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000833.47E-13285331No hitNo description
Gene3DG3DSA:4.10.280.101.1E-15285341IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd048733.84E-8394454No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0010444Biological Processguard mother cell differentiation
GO:0050826Biological Processresponse to freezing
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 466 aa     Download sequence    Send to blast
MNGDGVWLDG AGQRSPAAND GGDNDESASW VRNPEENWFN NPQPPPNPHD SQILLHSNQN  60
DFRFNGGFPL NPSENLLLLL QQSIDSSSSP LQPPFTLDAA SQQQQSFLAT KACIASLLSV  120
PTSSNNNNNN PFDEFGFDSG FLGQIHGNQT PISMNFAGMS SRPEFLSSRP IPPPGNITGG  180
NGFSPLEFEG VANGVFENRA KVLKPLEVLA SSGSQPTLFQ KRAAMRQSSS SKLCNSESSS  240
EMRRSSYERE VDDTGTGIID ISGLNYESDE HNKGKKKGMP AKNLMAERRR RKKLNDRLYM  300
LRSVVPKISK MDRASILGDA IDYLKELLQR INDLHTELES TPPSSSGLHP LTPTPQTLSY  360
RVKEELCPSS SLPSPKGQQA RVEVRLREGK AVNIHMFCGR RPGLLLSTMR ALDNLGLDVQ  420
QAVISCFNGF ALDVFHAEQC QEGHDMMPEQ IKAVLLDTAG YAGLL*
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1274292KKKGMPAKNLMAERRRRKK
2286293ERRRRKKL
Functional Description ? help Back to Top
Source Description
UniProtMediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA (PubMed:18641265). Functions as a dimer with SPCH during stomatal initiation (PubMed:18641265, PubMed:28507175). {ECO:0000269|PubMed:18641265, ECO:0000269|PubMed:28507175}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapThhalv10007566m
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK1180110.0AK118011.1 Arabidopsis thaliana At1g12860 mRNA for putative bHLH transcription factor (bHLH033), complete cds, clone: RAFL19-21-N13.
GenBankBT0053770.0BT005377.1 Arabidopsis thaliana At1g12860 mRNA, complete cds.
GenBankEU3696700.0EU369670.1 Arabidopsis thaliana bHLH protein (SCREAM2) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006417184.10.0transcription factor SCREAM2
SwissprotQ9LPW30.0SCRM2_ARATH; Transcription factor SCREAM2
TrEMBLV4KZT90.0V4KZT9_EUTSA; Uncharacterized protein
STRINGXP_006417184.10.0(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM19522782
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G12860.10.0bHLH family protein
Publications ? help Back to Top
  1. Tarasov VA,Khadeeva NV,Mel'nik VA,Ezhova TA,Shestakov SV
    The Atlg12860 gene of Arabidopsis thaliana determines cathelicidin-like antimicrobial activity.
    Dokl. Biol. Sci., 2009.
    [PMID:19760875]
  2. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Emmerstorfer A, et al.
    Over-expression of ICE2 stabilizes cytochrome P450 reductase in Saccharomyces cerevisiae and Pichia pastoris.
    Biotechnol J, 2015. 10(4): p. 623-35
    [PMID:25641738]
  5. Lee HG,Seo PJ
    The MYB96-HHP module integrates cold and abscisic acid signaling to activate the CBF-COR pathway in Arabidopsis.
    Plant J., 2015. 82(6): p. 962-77
    [PMID:25912720]
  6. Raissig MT,Abrash E,Bettadapur A,Vogel JP,Bergmann DC
    Grasses use an alternatively wired bHLH transcription factor network to establish stomatal identity.
    Proc. Natl. Acad. Sci. U.S.A., 2016. 113(29): p. 8326-31
    [PMID:27382177]
  7. Fu ZW,Wang YL,Lu YT,Yuan TT
    Nitric oxide is involved in stomatal development by modulating the expression of stomatal regulator genes in Arabidopsis.
    Plant Sci., 2016. 252: p. 282-289
    [PMID:27717464]
  8. de Marcos A, et al.
    A Mutation in the bHLH Domain of the SPCH Transcription Factor Uncovers a BR-Dependent Mechanism for Stomatal Development.
    Plant Physiol., 2017. 174(2): p. 823-842
    [PMID:28507175]