PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thhalv10022620m
Common NameEUTSA_v10022620mg
Organism
Eutrema salsugineum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema
Family bHLH
Protein Properties Length: 575aa    MW: 65333.8 Da    PI: 4.9374
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thhalv10022620mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH40.26e-13318363555
                      HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
              HLH   5 hnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                      + ++ErrRR+++N+++  Lr+l+P       +Kl+ a+iL  A++Y+k+Lq
  Thhalv10022620m 318 NLMAERRRRKKLNDRLYALRSLVPRI-----TKLDRASILGDAINYVKELQ 363
                      5589*********************7.....7******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142155.6E-1810148IPR025610Transcription factor MYC/MYB N-terminal
CDDcd000831.44E-14312365No hitNo description
SuperFamilySSF474599.42E-18312378IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088816.831313362IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.7E-10318363IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003533.7E-16319368IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.1E-16320376IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009555Biological Processpollen development
GO:0048657Biological Processanther wall tapetum cell differentiation
GO:0005634Cellular Componentnucleus
GO:0000978Molecular FunctionRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 575 aa     Download sequence    Send to blast
MESSMQNLLE KLRPLVGARA WDYCVLWKLN EDQRFVKWMG CCCGGTQLIE DNGTEEFSFG  60
GCRDVMFHHP RTKSCEFLAH LPSSIPLDSG IYAETLLTNQ TGWLSESSEP GFMQETICTR  120
VLIPIPGGLV ELFATRHVAE DQNVVDFVMG HCNIMIDDTA TINMMVADEV ESKPYGMLSS  180
EMHPKGSKDE DMMNLPSSYD ISADQIRLNF MPQMSDYEAQ QQHLKMKSDY HHHQALGYLP  240
ENSNKEMMGM NPFNTVSEDG IPVIGEPSLL VNEQQVGNDK ETNENGRLDT GSDCSDQIDD  300
EDDPKYKKKS GKQAQAKNLM AERRRRKKLN DRLYALRSLV PRITKLDRAS ILGDAINYVK  360
ELQSEAKELQ DELEENSETE DGSNRQQGGM SLNGTVVTAF HQGLSCNSNV PNLKQDVDLE  420
NYNDKGQEME PQVDVAQLDG REFFVKVICE YKPRGFTRLM EALDSLGLEV TNANTTRFLS  480
LVSNVFKVEK NDSEMVQAEH VRNSLLEITR NTSRGWHDDQ MATGSMQNEK NEVDYQHYDD  540
HHHQGGHLNL HDHQMNQSAH HHHHHQHINH YQNQ*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A7e-13311375273Transcription factor MYC2
5gnj_B7e-13311375273Transcription factor MYC2
5gnj_E7e-13311375273Transcription factor MYC2
5gnj_F7e-13311375273Transcription factor MYC2
5gnj_G7e-13311375273Transcription factor MYC2
5gnj_I7e-13311375273Transcription factor MYC2
5gnj_M7e-13311375273Transcription factor MYC2
5gnj_N7e-13311375273Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1306327KKKSGKQAQAKNLMAERRRRKK
2321328ERRRRKKL
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Plays a crucial role in tapetum development. Required for male fertility and pollen differentiation, especially during the post-meiotic transcriptional regulation of microspore development within the developing anther (PubMed:12535353). Binds E-box regions in the AHL16/TEK promoter. {ECO:0000269|PubMed:12535353, ECO:0000269|PubMed:24804694}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapThhalv10022620m
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAJ5119910.0AJ511991.1 Brassica napus mRNA for bHLH transcription factor.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006409372.10.0transcription factor ABORTED MICROSPORES
SwissprotQ9ZVX20.0AMS_ARATH; Transcription factor ABORTED MICROSPORES
TrEMBLV4LJU20.0V4LJU2_EUTSA; Uncharacterized protein
STRINGXP_006409372.10.0(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM75892741
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G16910.10.0bHLH family protein
Publications ? help Back to Top
  1. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  2. Jiang J,Zhang Z,Cao J
    Pollen wall development: the associated enzymes and metabolic pathways.
    Plant Biol (Stuttg), 2013. 15(2): p. 249-63
    [PMID:23252839]
  3. Xu J, et al.
    ABORTED MICROSPORES Acts as a Master Regulator of Pollen Wall Formation in Arabidopsis.
    Plant Cell, 2014. 26(4): p. 1544-1556
    [PMID:24781116]
  4. Qian H, et al.
    Trace concentrations of imazethapyr (IM) affect floral organs development and reproduction in Arabidopsis thaliana: IM-induced inhibition of key genes regulating anther and pollen biosynthesis.
    Ecotoxicology, 2015. 24(1): p. 163-71
    [PMID:25348600]
  5. Xiong SX, et al.
    The transcription factors MS188 and AMS form a complex to activate the expression of CYP703A2 for sporopollenin biosynthesis in Arabidopsis thaliana.
    Plant J., 2016. 88(6): p. 936-946
    [PMID:27460657]
  6. Ferguson AC, et al.
    Biphasic regulation of the transcription factor ABORTED MICROSPORES (AMS) is essential for tapetum and pollen development in Arabidopsis.
    New Phytol., 2017. 213(2): p. 778-790
    [PMID:27787905]
  7. Lou Y, et al.
    Positive regulation of AMS by TDF1 and the formation of a TDF1-AMS complex are required for anther development in Arabidopsis thaliana.
    New Phytol., 2018. 217(1): p. 378-391
    [PMID:28940573]
  8. Bi H,Fan W,Zhang P
    C4 Protein of Sweet Potato Leaf Curl Virus Regulates Brassinosteroid Signaling Pathway through Interaction with AtBIN2 and Affects Male Fertility in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1689
    [PMID:29021807]